Find 5 Star Hotels in Santo Domingo
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Santo Domingo 5 Star Hotels
Compare Santo Domingo 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santo Domingo.

Alaya Yoga & Surf & Retreat
Venao, Canas, Los Santos
9.6/10 Exceptional! (16 reviews)
Still don't see what you're looking for?
See all properties in Santo Domingo.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Santo Domingo Hotel Reviews
Frequently asked questions
Explore a world of travel with Expedia
Santo Domingo Hotels by Star Rating
Stay near popular Santo Domingo attractions
- Hotels near Cerro La Teta
- Hotels near Playa El Toro
- Hotels near El Uverito Beach
- Hotels near Playa Las Comadres
- Hotels near Playa El Arenal
- Hotels near Playa El Rompio
- Hotels near Belisario Porras Park
- Hotels near Iglesia Santa Librada
- Hotels near Iguana Island National Park
- Hotels near Catedral San Juan Bautista
- Hotels near Church of St. Athanasius
- Hotels near Chitre Golf Club
- Hotels near Herrera Museum
- Hotels near Museo de la Nacionalidad
- Hotels near Museo Manuel F Zárate
- Hotels near Academy of Customs & Traditions Gabriel Villarreal
- Hotels near Museo Belisario Porras
- Hotels near Isla de Cañas
Explore more hotels
- Hotel La Esperanza
- 1st Floor Beach House Apartment just steps from the beach!
- Beautiful Beach House and Casita at Playa Uverito, Las Tablas Panama
- Resting cabin with a unique garden, swimming pool and Panamanian traditions.
- Hostal Casa de Quincha
- Beautiful house in Costa Pedas
- Casa de Campo Pedasi
- 2nd Floor Beach House Apartment just steps from the beach!
- Zenquility Inn & Tavern
- Ocean Breeze Cove - Adults Only - Luxury Retreat
- Beautiful Home in Residenciales Cubita
- Hotel Piamonte
- DE GATTIS HOUSE NEWLY BUILT APARTMENTS A FEW KM FROM PLAYA VENAO
- Cuartos independientes con baño privado
- Pedasi Nature Paradise
- Minimalist House In Chitre
- RELAX HOSTEL
- Villas Don Pablo
- Uverito Beach House is a 2 Bed/2 Bath house just steps from the beach!
- Eye of Water Private Home with infinity pool and amazing views of Pacific Coast