Find All South Carolina Midlands Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All South Carolina Midlands Hotels
We have found 3280 South Carolina Midlands Hotels
- Hampton Inn Sumter
- Quality Inn Newberry
- Super 8 by Wyndham Santee
- Winton Inn & Suites
- Gerner by IHG
- Lookaway Inn
- Super 8 by Wyndham Manning
- Studio 6 West Columbia, SC - Airport
- Quality Inn Hartsville
- Quality Inn & Suites Richburg I-77
- Best Inn of Manning
- Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG
- Hampton Inn Columbia Northeast - Fort Jackson Area
- Red Roof Inn Santee
- Quality Inn & Suites Lake City
- Tru by Hilton Sumter
- Rodeway Inn & Suites Fort Jackson
- Candlewood Suites, Columbia/Ft. Jackson by IHG
- Spark by Hilton Sumter
- Econo Lodge Aiken Central
- Days Inn by Wyndham Lake City
- Holiday Inn Express Sumter by IHG
- Quality Inn Aiken North
- Days Inn by Wyndham Barnwell
- Starlight Stays
- Red Roof Inn Bishopville
- Budget Inn Timmonsville
- OYO Hotel Richburg SC I-77
- Studio 6 Florence , SC
- Sunset Inn Manning I 95
- Days Inn by Wyndham Columbia
- Carolina Lodge
- SpringHill Suites Sumter
- Landsford Inn
- Quality Inn Kingstree North
- Knights Inn Aiken
- Americas Best Value Inn Winnsboro, SC
- American Inn
- Super 8 by Wyndham Florence SC I-95 North / Hwy 76
- Suburban Studios Orangeburg
- Studio 6 Rock Hill, SC – Cherry Road
- Days Inn by Wyndham Orangeburg South
- Bar-Mel Inn
- Luxury Carriage House Suite on the Lake.
- Raceway Inn
- Imperial motel
- Fairfield by Marriott Inn & Suites Columbia Lexington
- Chesnut Cottage Inn
- Econo Lodge Cheraw Market Street
- Suburban Studios Florence I-95
- Sunrise Inn
- Budget Inn Express
- Rodeway Inn Florence Downtown
- Affordable Suites Sumter SC
- Inn Upon Moon River Plantation
- Crown Inn By Oyo Orangeburg Hwy 301
- Rodeway Inn Greenwood
- Executive Inn Chester
- American Inn
- 15 acre luxury farmhouse with pool in Blythewood, SC, Circa 1788.
- MainStay Suites Florence - Darlington
- The Hemlock Lodge, Luxury Lakeside Log Cabin Estate. Hot tub, Dock, Boat Lift!
- Shandon’s Best: Bubba’s Tranquil Treehouse Permit # STR-000211-2025
- The Monarch Room at The Deodara
- 2 Bedroom Suite w/ Kitchen + Free Parking & Pool
- Burrell and Flynn's Farm
- Chesterfield Hotel by OYO Hwy 9
- Amazing Studio Guesthouse, in beautiful Columbia Lake community suburb.
- Waterfront Condo on Lake Marion
- Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!
- Hotel Everett
- Eagle Inn Sumter
- Country Inn & Suites by Radisson, Rock Hill, SC
- Studio w/ Kitchen | Free Breakfast & Parking
- Days Inn by Wyndham Blythewood North Columbia
- Hotel O Deluxe Inn Kingstree Sc Hwy 52
- Economy Inn
- Candlewood Suites Sumter by IHG
- The Farm House
- Guest Lodge Pageland
- Lazy Dog Acres
- Americas Best Value Inn & Suites Sumter
- Burch's Carriage House
- LivSmart Studios by Hilton Columbia Greystone