Central San Diego, CA Aparthotels from AED 387

A red train on tracks, palm trees, and modern buildings.

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Our top choices for Central San Diego aparthotels

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

1. City24 Hotel Little Italy Mission Hills

Middletown

Stephanie

AED 606 total

includes taxes & fees

2 Dec - 3 Dec

A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

2. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Hillcrest

Victor

AED 387 total

includes taxes & fees

8 Nov - 9 Nov

A spacious lounge area with a sofa, a coffee table, and a bar with stools.

3. Marriott Vacation Club®, San Diego

Downtown San Diego

Dirosia

AED 613 total

includes taxes & fees

19 Nov - 20 Nov

A modern lobby with a green sofa, a wooden accent wall, and a large plant.

4. Little Italy Inn - Limited Service Apart Hotel

Downtown San Diego

Olivia

AED 416 total

includes taxes & fees

9 Nov - 10 Nov

A modern building with a well-lit entrance, surrounded by palm trees and a landscaped garden.

5. Winners Circle Solana Beach Del Mar Resort

Solana Beach

Lea

AED 642 total

includes taxes & fees

8 Nov - 9 Nov

A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

6. Kasa Gaslamp Quarter San Diego

Downtown San Diego

Eric

AED 445 total

includes taxes & fees

8 Nov - 9 Nov

🛋️ Seamless flow between living, dining, and sleeping areas — ideal for entertaining or staying connected during an extended stay.

7. The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!

Downtown San Diego

AED 993 total

includes taxes & fees

6 Dec - 7 Dec

A dining table set with white bowls, wine glasses, and a vase with flowers.

8. The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!

Downtown San Diego

AED 1,218 total

includes taxes & fees

9 Nov - 10 Nov

A pathway leading to a white building with balconies, surrounded by palm trees and greenery.

9. A Slice of Paradise inside the Omni La Costa resort, Carlsbad! Villa 6534

La Costa

Jill O.

AED 1,890 total

includes taxes & fees

7 Nov - 8 Nov

An outdoor seating area with tables and chairs, a pergola with a canopy, and a building with large windows in the background.

10. ADA Suite w/ Roll-in Shower | Free Breakfast

Bressi Ranch

11. Spacious Suite w/ Kitchen | Breakfast Included!

Bressi Ranch

AED 1,759 total

includes taxes & fees

19 Nov - 20 Nov

A rooftop pool with lounge chairs and a city skyline in the background.

12. Kasa Little Italy San Diego

Downtown San Diego

Nirmeen

AED 1,137 total

includes taxes & fees

8 Nov - 9 Nov

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Top Central San Diego Hotel Reviews

Kings Inn San Diego

10/10 Excellent

"The room was very clean. The staff were very helpful when checking in and out."

Hilton Garden Inn San Diego Old Town/SeaWorld Area

10/10 Excellent

"Room was clean and bed was comfortable. The hotel did change policies though as they used to give you bottled water each day at the desk if you asked. I checked in with no issues and used the Hilton app to check out without having to visit the front desk. Housekeeping is every other day but you can ask for daily if you wish. Housekeeping did a great job cleaning but I did have to ask for face towels and they did not replace those when the room was cleaned. However, they were quickly delivered. This place is great because of its proximity to old town and to the MTS trolley. I decided to just use the trolley for my trip, and then do short Uber runs from that to my final destination. You can also catch a free roundtrip shuttle to the airport which is very convenient. I will be staying again."

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Our top choices for Central San Diego aparthotels

1. City24 Hotel Little Italy Mission Hills