The Best Hotels Closest to DNA Lounge in San Francisco for 2026

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Our top choices for DNA Lounge hotels

A modern building facade with vertical wooden slats, a glass entrance, and a sign reading "La Société Bar & Cafe".

1. Hyatt Regency San Francisco Downtown SOMA

South of Market, 1.9 km from DNA Lounge

Julio

AED 964 total

includes taxes & fees

22 Nov - 23 Nov

A buffet area with a variety of food items and condiments.

2. citizenM San Francisco Union Square

Union Square, 1.7 km from DNA Lounge

Patrice

AED 501 total

includes taxes & fees

23 Nov - 24 Nov

An indoor swimming pool with multiple lounge chairs and a high ceiling with skylights.

3. Hotel Nikko San Francisco

Union Square, 1.7 km from DNA Lounge

Jessica

AED 937 total

includes taxes & fees

22 Nov - 23 Nov

A restaurant interior with wooden tables and booths, a tiled pillar, and a unique ceiling design.

4. Hotel G San Francisco

1.8 km from DNA Lounge

matthew

AED 640 total

includes taxes & fees

29 Nov - 30 Nov

An outdoor dining area with a view of a vineyard and a lake.

5. The St. Regis San Francisco

South of Market, 1.9 km from DNA Lounge

Eve

AED 2,125 total

includes taxes & fees

22 Nov - 23 Nov

A rooftop terrace with outdoor seating, a view of the city skyline, and modern buildings in the background.

6. Four Seasons Hotel San Francisco

South of Market, 1.9 km from DNA Lounge

Sun Ding

AED 2,239 total

includes taxes & fees

20 Nov - 21 Nov

A hotel room with two beds, a desk, a chair, a large window, and a bathroom with a sink and mirror.

7. The Grove Inn

1.8 km from DNA Lounge

Isabelle

AED 488 total

includes taxes & fees

29 Nov - 30 Nov

A modern living room with a sofa, two armchairs, a coffee table, and a fireplace.

8. InterContinental San Francisco by IHG

South of Market, 1.4 km from DNA Lounge

Luis

AED 912 total

includes taxes & fees

28 Nov - 29 Nov

A grand lobby with a marble staircase, a chandelier, and a teal sofa.

9. The Marker Union Square San Francisco

1.7 km from DNA Lounge

Samantha

AED 637 total

includes taxes & fees

24 Nov - 25 Nov

A potted succulent plant on a balcony with a metal railing and a chair in the background.

10. Becks Motor Lodge

1.8 km from DNA Lounge

Jackelin

AED 680 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a grey sofa, a dining table, a TV, and a large window with curtains.

11. The Clift Royal Sonesta San Francisco

1.8 km from DNA Lounge

Randall Gray

AED 1,004 total

includes taxes & fees

20 Nov - 21 Nov

A lobby with a brown leather sofa, a wooden coffee table with books, a blue staircase, and a wall with a map and text.

12. HI San Francisco Downtown Hostel

Union Square, 1.7 km from DNA Lounge

Raven

AED 304 total

includes taxes & fees

21 Nov - 22 Nov

A cityscape with modern high-rise buildings, including a distinctive building with a large clock and a theater named "Blue Shield of California Theater".

13. W San Francisco

South Park, 1.9 km from DNA Lounge

Brett

AED 899 total

includes taxes & fees

20 Nov - 21 Nov

A rooftop bar with tables, chairs, and a sofa, overlooking a city skyline at dusk.

14. Canopy by Hilton San Francisco SoMa

South Park, 1.6 km from DNA Lounge

ALEXIS

AED 861 total

includes taxes & fees

25 Nov - 26 Nov

A woman sitting at a table with a drink, in a modern interior with abstract sculptures and indoor plants.

15. JW Marriott San Francisco Union Square

1.9 km from DNA Lounge

Caroline

AED 998 total

includes taxes & fees

22 Nov - 23 Nov

A hotel with a modern design, featuring a prominent 'PARC 55' sign, multiple floors, and a corner location with a visible street view.

16. Parc 55 San Francisco - A Hilton Hotel

Union Square, 1.6 km from DNA Lounge

Elideth

AED 635 total

includes taxes & fees

13 Nov - 14 Nov

A modern hotel lobby with a large wooden bar, bar stools, a patterned floor, and a seating area with a sofa and cushions.

17. Courtyard by Marriott San Francisco Downtown/Van Ness Ave.

1.8 km from DNA Lounge

Sue

AED 774 total

includes taxes & fees

22 Nov - 23 Nov

A modern interior with round tables and chairs, a patterned rug, and a large wooden wall.

18. Hotel Zelos San Francisco

South of Market, 1.7 km from DNA Lounge

Christian

AED 871 total

includes taxes & fees

20 Nov - 21 Nov

A bar area with a wooden ceiling, a bar counter, and multiple bar stools.

19. The Phoenix Hotel

1.4 km from DNA Lounge

Katherine

AED 584 total

includes taxes & fees

1 Dec - 2 Dec

A hotel room with a bed, a sofa, a small table, a chair, and a desk.

20. Symphony Inn

1.2 km from DNA Lounge

Michael

AED 504 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to DNA Lounge

Property	Property class	Guest rating
Hyatt Regency San Francisco Downtown SOMA	4.0 star property	9.4 Exceptional 1,325 reviews	View
citizenM San Francisco Union Square	4.0 star property	9.4 Exceptional 1,455 reviews	View
Hotel Nikko San Francisco	4.5 star property	9.4 Exceptional 3,170 reviews	View
Hotel G San Francisco	4.0 star property	9.2 Wonderful 1,006 reviews	View
The St. Regis San Francisco	5.0 star property	9.4 Exceptional 749 reviews	View

Hotels recommended for families near DNA Lounge

A dining table with plates of food, two wine glasses, and cutlery, set against a cityscape view.

Marines Memorial Club & Hotel

Union Square

AED 706 total

includes taxes & fees

8 Nov - 9 Nov

Top DNA Lounge Hotel Reviews

Hotel Fiona

10/10 Excellent

"We had a wonderful stay! The hotel was cute, clean, and surprisingly spacious, with really nice bathrooms. Despite being close to the Tenderloin, we felt safe and comfortable inside the hotel. The surrounding area is a little rough, but the hotel offers a few parking spots and locks your car in securely overnight, which was a huge plus and gave us peace of mind. The staff was absolutely fantastic—everyone we encountered was friendly, welcoming, and incredibly helpful. Their hospitality really made our stay even better. Overall, a great little hotel with clean, comfortable rooms, secure parking, and outstanding staff. We would definitely stay here again!"

The Pickwick Hotel

8/10 Good

"Mr. Douglas was fantastic at the front desk. The rooms were pretty small, and the walls were paper thin. The beds were very comfortable. It was a very walkable location, close to so many things. Keep in mind that the dumpsters get dumped every night and that can happen any time between 3 and 5 am, so if you’re a light sleeper, that could be rough. I would stay there again."

Chancellor Hotel on Union Square

10/10 Excellent

"Our visit was wonderful. The staff was incredible, from the doorman who greeted us to the desk staff to the amazing bartender who gave us some great tips. The hotel is in a great location, with the cable cars, restaurants and lots of high-end shops nearby. The hotel is very historic, so it lacks some things visitors might be used to, such as air conditioning and a roomy elevator, but it makes up for that with a lot of attention to small details, such as a coffee machine that offers a variety of selections, and apples and cookies in the lobby 24/7. There is even a filled candy jar in the room. There is also a small bar in the lobby that offers a full drink selection and free popcorn. Overall, we could not have been happier with this hotel."

Hampton Inn San Francisco Downtown/Convention Center

8/10 Good

"Room was clean and staff were friendly. I only stayed for a night so I didn’t take advantage of too many amenities. The breakfast downstairs was pretty good; sufficient selection to start my day off. I should have looked into the parking situation ahead of time but that was my only gripe. Valet was the best option to avoid the parking ticket I received after parking on the street overnight."

Other attractions near DNA Lounge

Audio Nightclub

After visiting Audio Nightclub, make a plan to see the other sights and activities in San Francisco. Experience the entertainment choices and acclaimed art scene in this vibrant area.

See properties

Frequently asked questions

What's the area like around DNA Lounge?

DNA Lounge is located in San Francisco. This metropolitan area is known for its stunning architecture and top museums. If you're looking for a convenient place to stay, check out the 281 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near DNA Lounge?

The Pickwick Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a fitness center. It's located just a short 0.9 mi (1.4 km) from DNA Lounge. Other good choices within a short distance include BEI San Francisco, Trademark Collection by Wyndham and Parc 55 San Francisco - A Hilton Hotel.

How many hotels are there near DNA Lounge?

Expedia has 281 hotels and other accommodations within a mile from DNA Lounge.

If I need to cancel the hotel reservation for my stay near DNA Lounge, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best options available near DNA Lounge.

Where can I learn more about changing or cancelling my trip in the area near DNA Lounge?

For additional details about rescheduling or cancelling your stay near DNA Lounge, go to https://www.expedia.com/service/.

What can I see and do near DNA Lounge?

Study the collections at Asian Art Museum of San Francisco, San Francisco Museum of Modern Art, or Cable Car Museum. Sights like Golden Gate Bridge, San Francisco Mint, and Painted Ladies are must-sees while exploring the area. You can check out the local talent at Bill Graham Civic Auditorium, Orpheum Theatre, and SFJAZZ Center.

How can I get to DNA Lounge?

With so many transportation options, seeing the area around DNA Lounge is easy. Take advantage of metro transit at Market St & 5th St Stop, Market St & Taylor St Stop, and Powell St & Market St Stop. If you're taking a train into town, San Francisco Station is the closest station to Downtown San Francisco.

Find hotels near DNA Lounge, San Francisco from AED 304

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Our top choices for DNA Lounge hotels

1. Hyatt Regency San Francisco Downtown SOMA

2. citizenM San Francisco Union Square

3. Hotel Nikko San Francisco

4. Hotel G San Francisco

5. The St. Regis San Francisco

6. Four Seasons Hotel San Francisco

7. The Grove Inn

8. InterContinental San Francisco by IHG

9. The Marker Union Square San Francisco

10. Becks Motor Lodge

11. The Clift Royal Sonesta San Francisco

12. HI San Francisco Downtown Hostel

13. W San Francisco

14. Canopy by Hilton San Francisco SoMa

15. JW Marriott San Francisco Union Square

16. Parc 55 San Francisco - A Hilton Hotel

17. Courtyard by Marriott San Francisco Downtown/Van Ness Ave.

18. Hotel Zelos San Francisco

19. The Phoenix Hotel

20. Symphony Inn

Compare popular hotels close to DNA Lounge

Hotels recommended for families near DNA Lounge

Marines Memorial Club & Hotel

Top DNA Lounge Hotel Reviews

Hotel Fiona

Other attractions near DNA Lounge

Audio Nightclub

Frequently asked questions