A tree-lined landscape with a river and fields.

Find hotels in East Prairie, MO from AED 243

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Check prices for these dates

Tonight
12 Aug - 13 Aug
Tomorrow
13 Aug - 14 Aug
This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

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Our top choices for East Prairie hotels

Reserve now, pay later
Hotel
Breakfast included
Cabin
Big Oak Tree State Park

1. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Bobby
AED 244
AED 271 total
includes taxes & fees
7 Sep - 8 Sep
The Riverstone Hotel Charleston-Sikeston

2. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
France
AED 219
AED 243 total
includes taxes & fees
16 Aug - 17 Aug
Super 8 by Wyndham Charleston/Sikeston East MO

3. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
AED 255
AED 282 total
includes taxes & fees
13 Aug - 14 Aug
Eagle Inn Charleston

4. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
Chevayon
AED 240
AED 274 total
includes taxes & fees
11 Sep - 12 Sep
Days Inn and Suites by Wyndham Sikeston

5. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Kevin
AED 350
AED 399 total
includes taxes & fees
23 Aug - 24 Aug
Best Western Plus Sikeston I-55

6. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
United States
William
AED 216
AED 257 total
includes taxes & fees
1 Sep - 2 Sep
Country Yard Inn and Suite

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Sharika West
AED 246
AED 280 total
includes taxes & fees
16 Aug - 17 Aug
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
United States
Starlette
AED 350
AED 399 total
includes taxes & fees
10 Sep - 11 Sep
Comfort Inn & Suites Sikeston I-55

9. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Sally
AED 408
AED 469 total
includes taxes & fees
17 Aug - 18 Aug
Drury Inn & Suites Sikeston, MO

10. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
michael
AED 356
AED 403 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Express & Suites Sikeston Southwest by IHG

11. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Brandi
AED 365
AED 414 total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn Sikeston

12. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
James
AED 231
AED 264 total
includes taxes & fees
13 Aug - 14 Aug
Super 8 by Wyndham Sikeston/Miner Area

13. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Lauren
AED 400
AED 453 total
includes taxes & fees
23 Aug - 24 Aug
TownePlace Suites by Marriott Sikeston

14. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Joni
AED 371
AED 420 total
includes taxes & fees
23 Aug - 24 Aug
Fairfield Inn & Suites by Marriott Sikeston

15. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
United States
Sharon
AED 264
AED 293 total
includes taxes & fees
19 Aug - 20 Aug
Quality Inn Cairo I-57

16. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
Marston
United States
Temera
AED 241
AED 276 total
includes taxes & fees
13 Aug - 14 Aug
Super 8 By Wyndham Marston

17. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
Marston
United States
Riley
AED 205
AED 254 total
includes taxes & fees
13 Aug - 14 Aug
Travel Inn Marston I-55 by Hotel O

18. Reelfoot Lake Inn

Reelfoot Lake Inn
Tiptonville
United States
Richard
AED 217
AED 270 total
includes taxes & fees
23 Aug - 24 Aug
Reelfoot Lake Inn

19. MainStay Suites at Discovery Park of America

MainStay Suites at Discovery Park of America
Union City
United States
Jamie
AED 403
AED 478 total
includes taxes & fees
27 Aug - 28 Aug
MainStay Suites at Discovery Park of America

20. Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
Union City
United States
Ben
AED 309
AED 366 total
includes taxes & fees
2 Sep - 3 Sep
Sleep Inn at Discovery Park of America
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Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
A tree-lined landscape with a river and fields.

Top East Prairie Hotel Reviews

Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

10/10 Excellent
"This property was one of the cleanest we have ever stayed at. They had one of the nicest coffee stations I have ever seen in a VRBO and everything you could need !"
Karen H. 4-night trip
Posted 18 hours ago
Duck Hunting, Fishing or Relaxing Family Vacation
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

8/10 Good
"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside the room door and flew into the room when you opened your door at night. The other thing that I did not like was the surprise $100 fee that I had to pay up front for potential damage to the room. This fee was returned during check out."
James 2-night trip
Posted 2 days ago
The Riverstone Hotel Charleston-Sikeston
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

8/10 Good
"Room was very clean. Property in general was very clean."
dal 2-night trip
Posted 2 days ago
Sleep Inn at Discovery Park of America
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Nice staff. Very accommodating."
Domingo 1-night trip
Posted 3 days ago
Super 8 by Wyndham Charleston/Sikeston East MO
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"the room was clean and had everything we needed for a 1 night stay!"
Bailee 1-night trip
Posted 3 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

10/10 Excellent
"Front desk was super helpful"
Richard 1-night trip
Posted 4 days ago
Best Western Plus Sikeston I-55
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

8/10 Good
"Convenient to the interstate. Close to food selection. Nice breakfast bar. Overall well maintained."
Ann 1-night trip
Posted 9 days ago
Comfort Inn & Suites Sikeston I-55
Reelfoot Lake Inn

Reelfoot Lake Inn

10/10 Excellent
"Clean"
paul 3-night trip
Posted 2 months ago
Reelfoot Lake Inn

More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
AED 240
AED 274 total
11 Sep - 12 Sep
includes taxes & fees
7.2/10 Good! (1,000 reviews)
Days Inn and Suites by Wyndham Sikeston
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

1111 BLue Heron Lane Union City TN
AED 309
AED 366 total
2 Sep - 3 Sep
includes taxes & fees
9.2/10 Wonderful! (422 reviews)
Sleep Inn at Discovery Park of America
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO
AED 350
AED 399 total
23 Aug - 24 Aug
includes taxes & fees
8.4/10 Very Good! (1,011 reviews)
Best Western Plus Sikeston I-55
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO
AED 356
AED 403 total
23 Aug - 24 Aug
includes taxes & fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
AED 365
AED 414 total
23 Aug - 24 Aug
includes taxes & fees
9/10 Wonderful! (607 reviews)
Hampton Inn Sikeston
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

810 BREAM BOULEVARD Union City TN
AED 404
AED 480 total
23 Aug - 24 Aug
includes taxes & fees
Holiday Inn Express & Suites Union City by IHG

Hotels in East Prairie with star-rating

Find out more about East Prairie

Top reasons to visit East Prairie

  • Scenic Trails: East Prairie features beautiful landscapes and trails perfect for hiking and outdoor adventures.
  • Romantic Getaways: Ideal for couples, the town offers charming settings for a cozy getaway.
  • Local History: Explore museums and historical sites that showcase the rich culture of the area.
  • Family-Friendly Parks: Enjoy lush parks that provide great spots for family excursions and picnics.
  • Comfortable Accommodations: A variety of hotels and motels cater to travelers' needs, ensuring a pleasant stay.

Find great hotels near East Prairie

Explore a variety of hotel accommodations in East Prairie, Missouri, ideal for travelers seeking comfort and convenience. Whether you're on a business trip, a family vacation, or traveling with pets, you'll find a range of options, including hotels and motels that cater to your needs. Discover the best hotels in East Prairie with positive reviews to ensure a pleasant stay in this charming town.

  • Days Inn and Suites by Wyndham Sikeston: Situated 17.7km from East Prairie, Days Inn and Suites by Wyndham Sikeston offers a welcoming atmosphere perfect for business travelers and pet owners alike. This hotel is designed with convenience in mind, featuring spacious rooms equipped with essential amenities. Guests can enjoy the comfort of a pet-friendly environment, with specific policies accommodating dogs and cats. The hotel also provides complimentary breakfast, making it easy to start your day off right. With its focus on practicality and comfort, this hotel is an excellent choice for those traveling with furry companions.
  • Drury Inn & Suites Sikeston, MO: Also located 17.7km from East Prairie, Drury Inn & Suites Sikeston, MO is a renowned 3-star hotel that embraces inclusivity, welcoming LGBTQIA travelers with open arms. The hotel boasts a variety of amenities designed for both business and leisure guests, including complimentary hot breakfast and evening snacks. Pet-friendly rooms are available with certain restrictions for dogs and cats, ensuring that your furry friends can join you on your journey. The inviting atmosphere and commitment to exceptional service make this hotel a favorite among travelers seeking comfort and community.
  • Pear Tree Inn Sikeston: Just 17.7km from East Prairie, Pear Tree Inn Sikeston caters to families, business travelers, and pet owners with its warm hospitality and thoughtful amenities. The hotel features family-friendly services, including complimentary cribs for younger guests, making it an ideal choice for those traveling with children. Pets are welcome too, with specific policies for dogs and cats. Guests can enjoy a cozy stay with comfortable accommodations and a complimentary breakfast that caters to all ages. Pear Tree Inn Sikeston strikes a balance between family-friendly warmth and professional service, ensuring a pleasant stay for everyone.

Where to stay near East Prairie

Discover the charm of East Prairie, Missouri, where outdoor enthusiasts and romantic getaways thrive. Just a short drive from Sikeston, explore lush parks and scenic open spaces perfect for family-friendly excursions. Enjoy the warm atmosphere filled with friendly people and delightful shopping experiences. Whether you're fishing, hiking, or simply relaxing, East Prairie offers a serene escape that will leave you refreshed and inspired.

  • Sikeston: Located 20.9km from East Prairie, Sikeston is a vibrant city known for its outdoor and family-friendly experiences. The city attracts visitors year-round, with peak seasons from June to August and December to February. Sikeston offers a variety of recreational areas, shopping centers, and educational venues. Notable attractions include a scenic lake and an event conference venue, making it an ideal spot for both relaxation and activities. Whether you're enjoying a day outdoors or exploring local shops, Sikeston provides a welcoming atmosphere for travelers.
  • Charleston: Just 16.1km away from East Prairie, Charleston is a charming city perfect for those seeking outdoor adventures and captivating scenery. Visitor numbers peak in April and from June to July, with a slight decline from October to December. Charleston boasts numerous recreational areas and shopping centers, alongside educational opportunities. The city is home to beautiful landmarks such as a national state park and various historic sites, offering a glimpse into the area's rich history. Nature enthusiasts and adventure seekers will find plenty to explore in Charleston.
  • Bertrand: Also located 16.1km from East Prairie, Bertrand is a picturesque city that attracts visitors for its outdoor adventures and scenic views. With peak travel periods in April, August, and from December to January, Bertrand offers a wealth of natural beauty. The nearby national park, lush forests, and serene lakes provide ample opportunities for hiking, fishing, and enjoying nature. Bertrand is perfect for those looking to escape the hustle and bustle of city life while immersing themselves in the great outdoors.

Things to do near East Prairie

East Prairie, Missouri, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy scenic trails, a recreational area, and opportunities for skiing. Major attractions include the beautiful landscapes of the prairie and various local tourism experiences that showcase the area's natural beauty. Whether you're looking for adventure or relaxation, East Prairie offers a charming escape for all types of travelers.

Shopping

If you're up for a drive, County Market Place is a shopping center located 49.9km away from East Prairie. This venue offers a blend of city, family, and business vibes, making it a great spot for finding unique gifts and souvenirs during your visit.

Recreation

Experience tranquility at the East Prairie Wellness Center, offering yoga classes and holistic therapies in a calming environment. For outdoor fun, visit the nearby Lake County Park, where you can enjoy fishing, hiking trails, and picnicking amidst nature's beauty.

Adventure

In East Prairie, explore the beautiful landscapes at the nearby Mingo National Wildlife Refuge, ideal for hiking and birdwatching. Experience fishing at the local lakes, or try your hand at kayaking for an exciting adventure on the water, surrounded by nature's beauty.

Nightlife

In East Prairie, the Union City Masquerade Theatre, located 49.9km away, is a fantastic spot for a romantic night out, featuring captivating performances that blend entertainment and culture, perfect for immersing yourself in the local arts scene.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for East Prairie

To save money on your trip to East Prairie, plan your visit between December and February when accommodation prices are lowest. Sundays offer the cheapest stays, while Saturdays are the most expensive. Utilize Expedia’s search tool to compare hotel rates and consider booking a package that includes flights and activities for additional savings. For budget-friendly transportation, walking is a great option since the town is easy to navigate. Look for free activities and local attractions to make the most of your visit without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in East Prairie are December to February, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in East Prairie is Sunday. The most expensive day to stay in East Prairie is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your options based on your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your East Prairie hotel reservation with your flights and activities through an Expedia package.

Find the best attractions in and around East Prairie

East Prairie, Missouri, offers a charming blend of outdoor adventures and cultural experiences perfect for a romantic getaway. Visitors can explore beautiful state parks, delve into local history at museums, or attend events at various venues. The area is ideal for those seeking scenic landscapes and engaging activities, with nearby attractions enhancing your exploration of this quaint town.

  • Big Oak Tree State Park: Experience the grandeur of one of the largest oak trees in the United States in this serene national park. With scenic trails and lush landscapes, it’s perfect for outdoor enthusiasts and those seeking adventure in nature.
  • Central Park: Located 20.9km from East Prairie, this vibrant urban park offers a family-friendly atmosphere with playgrounds, picnic areas, and walking paths. Enjoy a leisurely day surrounded by greenery while soaking up the lively city vibes.
  • Sikeston Depot Museum: Also 20.9km away, this art museum showcases the rich cultural history of the region. Explore fascinating exhibits and learn about local heritage while immersing yourself in the artistic ambiance.

Best time to go to East Prairie

The best time to visit East Prairie can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in East Prairie falls in July, when visitor numbers are moderately high and weather is mostly sunny with light rain. The coolest average temperature in East Prairie falls in January, visitor numbers are moderately high and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January36.3°F (2.4°C)Light RainMostly SunnyModerately HighSlightly Low
February39.4°F (4.1°C)Light RainMostly SunnyAverageSlightly Low
March49.5°F (9.7°C)Light RainMostly SunnyAverageAverage
April58.5°F (14.7°C)Light RainMostly SunnyAverageSlightly High
May68.2°F (20.1°C)Light RainMostly SunnyAverageAverage
June77.0°F (25.0°C)Light RainMostly SunnyModerately HighSlightly High
July79.5°F (26.4°C)Light RainMostly SunnyModerately HighAverage
August77.5°F (25.3°C)Light RainMostly SunnyAverageSlightly High
September72.1°F (22.3°C)Light RainMostly SunnyAverageAverage
October60.8°F (16.0°C)Light RainMostly SunnyModerately LowAverage
November48.6°F (9.2°C)Light RainMostly SunnyModerately LowAverage
December41.2°F (5.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to East Prairie

Traveling to East Prairie, Missouri, is convenient with several nearby airports. Paducah, KY (PAH-Barkley Regional) is 62.8km away, with hotel options like The Respite Bed and Breakfast and Harrah's Metropolis Hotel & Casino located nearby. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is 51.5km from East Prairie, offering accommodations such as the Drury Plaza Hotel and Courtyard by Marriott. Cairo, IL (CIR-Cairo Regional) is the closest, just 33.8km away, with options including Quality Inn and Super 8 by Wyndham. Each airport provides easy access to local hotels, ensuring a comfortable stay for visitors.

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Days Inn and Suites by Wyndham Sikeston and Holiday Inn Express & Suites Sikeston Southwest by IHG. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best vacation rentals that East Prairie has to offer?
Duck Hunting, Fishing or Relaxing Family Vacation: Visitors like this East Prairie vacation home rental. It is located on a lake and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
Where can I learn more about changing or cancelling my trip to East Prairie?
To access more information about rescheduling or cancelling your trip to East Prairie, click here.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 34 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.