Find hotels in East Prairie, MO from AED 229
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Compare 81 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1003)
The price is AED 231
AED 263 total
includes taxes & fees
9 Nov - 10 Nov

Hampton Inn Sikeston
Hampton Inn Sikeston
8.8 out of 10, Excellent, (417)
The price is AED 358
AED 406 total
includes taxes & fees
16 Nov - 17 Nov

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
8.6 out of 10, Excellent, (435)
The price is AED 371
AED 420 total
includes taxes & fees
14 Nov - 15 Nov

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1016)
The price is AED 309
AED 352 total
includes taxes & fees
9 Nov - 10 Nov

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8.4 out of 10, Very Good, (702)
The price is AED 207
AED 236 total
includes taxes & fees
5 Nov - 6 Nov

Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of America
9.0 out of 10, Wonderful, (296)
The price is AED 298
AED 353 total
includes taxes & fees
16 Nov - 17 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Top East Prairie Hotel Reviews

Drury Inn & Suites Sikeston, MO
10/10 Excellent
More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
The price is AED 231 per night from Nov 9 to Nov 10
AED 231
AED 263 total
9 Nov - 10 Nov
includes taxes & fees
7.2/10 Good! (1,002 reviews)
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Stay near popular East Prairie attractions
- Hotels near Big Oak Tree State Park
 - Hotels near Ohio River Valley
 - Hotels near Mississippi River
 - Hotels near Ohio River
 - Hotels near Discovery Park of America
 - Hotels near Reelfoot Lake State Park
 - Hotels near Columbus-Belmont State Park
 - Hotels near New Madrid Historical Museum
 - Hotels near Campbell's Point
 - Hotels near Sikeston Depot Museum
 - Hotels near Union City Masquerade Theatre
 - Hotels near Central Park
 - Hotels near Fort Defiance State Park
 - Hotels near Graham Park
 - Hotels near Marston Community Center
 - Hotels near Front Street Studio & Art Gallery
 
More Accommodation Types in East Prairie
East Prairie Hotels by Brand
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