Find hotels in East Prairie, MO from AED 229

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Compare 81 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.2 out of 10, Good, (1003)
"Clean and comfortable "
United States
Jim
The price is AED 231
AED 263 total
includes taxes & fees
9 Nov - 10 Nov
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston
2.5 star property
8.8 out of 10, Excellent, (417)
"Nice property and friendly staff."
United States
Nancy
The price is AED 358
AED 406 total
includes taxes & fees
16 Nov - 17 Nov
Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
8.6 out of 10, Excellent, (435)
"staff was friendly nothing to crazy about this hotel "
United States
Isaac
The price is AED 371
AED 420 total
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express & Suites Sikeston Southwest by IHG
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, (1016)
"Very convenient and great breakfast "
United States
Duwaine
The price is AED 309
AED 352 total
includes taxes & fees
9 Nov - 10 Nov
Best Western Plus Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
8.4 out of 10, Very Good, (702)
"Very quiet and comfortable "
United States
Lana
The price is AED 207
AED 236 total
includes taxes & fees
5 Nov - 6 Nov
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sleep Inn at Discovery Park of America
2.5 star property
9.0 out of 10, Wonderful, (296)
"Haven’t been to breakfast yet, but everything else has been wonderful! Very friendly and helpful staff. Quiet, even though several families with younger children also here! "
United States
Marcia
The price is AED 298
AED 353 total
includes taxes & fees
16 Nov - 17 Nov
Sleep Inn at Discovery Park of America
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
6.6 out of 10, (558)
"I enjoyed our stay"
United States
Alex
The price is AED 230
AED 262 total
includes taxes & fees
10 Nov - 11 Nov
Super 8 by Wyndham Sikeston/Miner Area
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1004)
"Everything was up to par. Enjoyed our stay. "
United States
Greg
The price is AED 283
AED 325 total
includes taxes & fees
9 Nov - 10 Nov
Pear Tree Inn Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.6 out of 10, (602)
"Tracey Allen checked me in. She was great!"
United States
Timothy
The price is AED 206
AED 229 total
includes taxes & fees
5 Nov - 6 Nov
Super 8 by Wyndham Charleston/Sikeston East MO
Comfort Inn & Suites Sikeston I-55
2.5 star property
8.4 out of 10, Very Good, (274)
"It was a very nice stay. The pool was clean and enjoying!"
United States
Lisa
The price is AED 325
AED 370 total
includes taxes & fees
9 Nov - 10 Nov
Comfort Inn & Suites Sikeston I-55
Hospitality House Union City I 69 / US 51
2.5 star property
6.8 out of 10, (353)
"I found the staff to be great. My room was large, clean and in good repair. Parking plentiful. I will definitely stay here again when in the area."
United States
Donna
The price is AED 200
AED 237 total
includes taxes & fees
5 Dec - 6 Dec
Hospitality House Union City I 69 / US 51
Quality Inn Union City US 51
2.5 star property
8.4 out of 10, Very Good, (479)
"Very nice staff"
United States
Jonathan
The price is AED 248
AED 294 total
includes taxes & fees
30 Nov - 1 Dec
Quality Inn Union City US 51
Country Hearth Inn & Suites Union City
2.5 star property
8.6 out of 10, Excellent, (543)
"Clean rooms, helpful and polite staff"
United States
Jennifer
The price is AED 264
AED 314 total
includes taxes & fees
5 Nov - 6 Nov
Country Hearth Inn & Suites Union City
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1002)
"Great staff. "
United States
Troy
The price is AED 345
AED 397 total
includes taxes & fees
23 Nov - 24 Nov
Drury Inn & Suites Sikeston, MO
Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
9.2 out of 10, Wonderful, (28)
"Nice hotel "
United States
April
The price is AED 371
AED 420 total
includes taxes & fees
13 Nov - 14 Nov
Fairfield Inn & Suites by Marriott Sikeston
Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, (271)
"We had a quiet and convenient one night stay. "
United States
Cindy
The price is AED 246
AED 273 total
includes taxes & fees
21 Nov - 22 Nov
Quality Inn Cairo I-57
Hampton Inn Union City
2.5 star property
9.4 out of 10, Exceptional, (158)
"It was peaceful and quiet"
United States
Erin
The price is AED 376
AED 447 total
includes taxes & fees
13 Nov - 14 Nov
Hampton Inn Union City
Holiday Inn Express & Suites Union City by IHG
2.5 star property
9.2 out of 10, Wonderful, (302)
"Everything was perfect especially the staff."
United States
Lawrence
The price is AED 389
AED 462 total
includes taxes & fees
21 Nov - 22 Nov
Holiday Inn Express & Suites Union City by IHG
Travel Inn
2.5 star property
5.8 out of 10, (113)
"Everything was great except for the wifi issue. They said there was wifi and gav3ca password but it didnt work. I called the front desk and was told they might havevto reset it. Not sure bc i never got to use it. "
United States
Michelle
Travel Inn
TownePlace Suites by Marriott Sikeston
3.0 star property
8.4 out of 10, Very Good, (5)
"I loved all of what this property had to offer "
United States
Christian
The price is AED 444
AED 503 total
includes taxes & fees
13 Nov - 14 Nov
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

More cheap stays in East Prairie

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Hampton Inn Sikeston and Sleep Inn at Discovery Park of America. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best vacation rentals that East Prairie has to offer?
Duck Hunting, Fishing or Relaxing Family Vacation: Visitors like this East Prairie vacation home rental. It is located on a lake and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
Where can I learn more about changing or cancelling my trip to East Prairie?
To access more information about rescheduling or cancelling your trip to East Prairie, click here.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 31 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.

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