The Best Hotels Closest to Florida Keys National Marine Sanctuary in Key West for 2026

Our top choices for Florida Keys National Marine Sanctuary hotels

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Almond Tree Inn Hotel - Adults Only

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

Jimmy

AED 1,015 total

includes taxes & fees

9 Jun - 10 Jun

Orchid Key Inn - Adults Only

Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary

Michael

AED 1,042 total

includes taxes & fees

9 Jun - 10 Jun

The Gardens Hotel

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Markus

AED 988 total

includes taxes & fees

28 Jun - 29 Jun

Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished

Simonton Court Historic Inn & Cottages

Historic Seaport, 1 km from Florida Keys National Marine Sanctuary

Olha

AED 613 total

includes taxes & fees

7 Jun - 8 Jun

The Marquesa Hotel

Old Town Key West, 1 km from Florida Keys National Marine Sanctuary

Julian

AED 1,483 total

includes taxes & fees

8 Jun - 9 Jun

The Conch House Heritage Inn

Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary

Lucy

AED 883 total

includes taxes & fees

9 Jun - 10 Jun

Douglas House - Adults Only

Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary

Matthew

AED 495 total

includes taxes & fees

9 Jun - 10 Jun

11 Gecko's Garden - Adults Only | Premium bedding, pillowtop beds, individually decorated

Tropical Inn

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Akhenaton

AED 790 total

includes taxes & fees

8 Jun - 9 Jun

Deluxe Suite, 1 King Bed, Private Pool | View from room

H2O Suites - Adults Only

Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary

Elizabeth

AED 1,607 total

includes taxes & fees

8 Jun - 9 Jun

L'Habitation Guest House

Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary

Megan

AED 574 total

includes taxes & fees

8 Jun - 9 Jun

Cigar House King Suite w/ Poolside porch | Balcony view

Island City House Hotel

Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary

Troy

AED 708 total

includes taxes & fees

10 Jun - 11 Jun

Duval House

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

gerald

AED 695 total

includes taxes & fees

8 Jun - 9 Jun

Marrero's Guest Mansion

Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary

Robert

AED 1,012 total

includes taxes & fees

23 Jun - 24 Jun

Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers

Ella's Cottages - Key West Historic Inns

Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary

Nanci

AED 818 total

includes taxes & fees

29 Jun - 30 Jun

Santa Maria Suites

Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary

Jill

AED 1,525 total

includes taxes & fees

21 Jun - 22 Jun

The Grand Guesthouse

Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary

Kim

AED 635 total

includes taxes & fees

9 Jun - 10 Jun

3 outdoor pools, a heated pool, sun loungers

Ambrosia Key West

Old Town Key West, 1 km from Florida Keys National Marine Sanctuary

Lori

AED 809 total

includes taxes & fees

7 Jun - 8 Jun

Southernmost House - Adult Exclusive

Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary

BOBBY J.

AED 1,255 total

includes taxes & fees

21 Jun - 22 Jun

Westwinds Inn

Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary

michael

AED 762 total

includes taxes & fees

9 Jun - 10 Jun

Paradise Inn Key West - Adults Only

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

Paul

AED 731 total

includes taxes & fees

15 Jun - 16 Jun

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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property	Property class	Guest rating
Almond Tree Inn Hotel - Adults Only	3.5 star property	10.0 Exceptional 1,005 reviews	View
Orchid Key Inn - Adults Only	3.5 star property	9.8 Exceptional 1,005 reviews	View
The Gardens Hotel	4.0 star property	9.8 Exceptional 1,001 reviews	View
Simonton Court Historic Inn & Cottages	2.5 star property	9.8 Exceptional 973 reviews	View
The Marquesa Hotel	3.5 star property	9.8 Exceptional 1,000 reviews	View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Wicker Guesthouse

10/10 Excellent

"Great location to attractions and restaurants. Convenient breakfast which was simple but good. Staff were courteous and helpful. Only negative was no table or chair in room, so you had to use chairs and tables in courtyard."

The Cabana Inn Key West - Adults Only

10/10 Excellent

"Great B&B in a great location in old town. Has all the charm of an old town Bed & Breakfast, a great refreshing pool, great continental breakfast and happy hour snacks. Nice landscaped grounds, plenty of spots to lounge/sunbathe/ read a book. Hot tub was cold which was a little disappointing. Bathroom could use a little upgrading but ample space. Would definitely stay again based on friendly staff and excellent location!"

Pier House Resort & Spa

10/10 Excellent

"My wife and I went down there for a four night stay and had a wonderful experience! We stayed in an ocean view room, which was absolutely beautiful. The staff was very friendly and helpful. The location could not have been better, and it is in walking distance to pretty much everything. The resort has its own private pool and beach, which was such a unique bonus. We were also very impressed by how intentional the resort is about wheelchair accessibility. My mother-in-law has ALS and is in a wheelchair, so we are already planning a trip to bringing her to this resort. We give it five stars!"

Southernmost Beach Resort and Guesthouses

6/10 Okay

"Look, we had a nice time. I put "OK" for your survey questions which may seem like we didn't enjoy. But, it would be hard to put "Good" for your survey answers. The beach was unusable due to dead, smelly seaweed that permeated the main pool, overall exterior (stairs, pool area, etc.) rooster poop, cigarette butts, etc. I particularly did not like the $65 resort fee per day. That was a surprise expense!"

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

4.4/5 (128 reviews)

You can spend an afternoon studying the exhibits at Florida Keys Eco - Discovery Center during your travels in Key West. Discover the area's lively bars and its lively festivals.

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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?

Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1537 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Florida Keys National Marine Sanctuary?

Adjacent to Florida Keys National Marine Sanctuary, Caribbean House is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and private balconies. Other good choices close by include La Concha Key West, Autograph Collection and Southernmost Beach Resort and Guesthouses.

How many hotels will I be able to find near Florida Keys National Marine Sanctuary?

Expedia has 1537 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.

If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?

Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.

Where can I learn more about changing or cancelling my trip in the area near Florida Keys National Marine Sanctuary?

To find more details about updating your stay near Florida Keys National Marine Sanctuary or cancelling it, head over to our customer service page.

What can I see and do near Florida Keys National Marine Sanctuary?

Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Key West Burlesque Theater, and Key West Film Society if you're interested in local theater.

Find hotels near Florida Keys National Marine Sanctuary, Key West from AED 495

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Our top choices for Florida Keys National Marine Sanctuary hotels

Almond Tree Inn Hotel - Adults Only

Orchid Key Inn - Adults Only

The Gardens Hotel

Simonton Court Historic Inn & Cottages

The Marquesa Hotel

The Conch House Heritage Inn

Douglas House - Adults Only

Tropical Inn

H2O Suites - Adults Only

L'Habitation Guest House

Island City House Hotel

Duval House

Marrero's Guest Mansion

Ella's Cottages - Key West Historic Inns

Santa Maria Suites

The Grand Guesthouse

Ambrosia Key West

Southernmost House - Adult Exclusive

Westwinds Inn

Paradise Inn Key West - Adults Only

Compare popular hotels close to Florida Keys National Marine Sanctuary

Top Florida Keys National Marine Sanctuary Hotel Reviews

Wicker Guesthouse

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

Frequently asked questions

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Hotels near popular Key West Attractions

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