The Best Hotels Closest to Florida Keys National Marine Sanctuary in Key West for 2026

Our top choices for Florida Keys National Marine Sanctuary hotels

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Almond Tree Inn Hotel - Adults Only

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

Jimmy

AED 827 total

includes taxes & fees

15 Jun - 16 Jun

Key West Villas

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Jennifer

AED 852 total

includes taxes & fees

16 Jun - 17 Jun

The Gardens Hotel

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Joseph

AED 988 total

includes taxes & fees

28 Jun - 29 Jun

Orchid Key Inn - Adults Only

Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary

Michael

AED 800 total

includes taxes & fees

15 Jun - 16 Jun

Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished

Simonton Court Historic Inn & Cottages

Historic Seaport, 1 km from Florida Keys National Marine Sanctuary

Francis

AED 588 total

includes taxes & fees

16 Jun - 17 Jun

The Conch House Heritage Inn

Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary

Lucy

AED 982 total

includes taxes & fees

21 Jun - 22 Jun

The Marquesa Hotel

Old Town Key West, 1 km from Florida Keys National Marine Sanctuary

Julian

AED 1,359 total

includes taxes & fees

21 Jun - 22 Jun

11 Gecko's Garden - Adults Only | Premium bedding, pillowtop beds, individually decorated

Tropical Inn

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Akhenaton

AED 623 total

includes taxes & fees

15 Jun - 16 Jun

Douglas House - Adults Only

Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary

Matthew

AED 566 total

includes taxes & fees

24 Jun - 25 Jun

Premium bedding, iron/ironing board, free WiFi, bed sheets

Weatherstation Inn

Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary

Bret

AED 740 total

includes taxes & fees

14 Jun - 15 Jun

Cigar House King Suite w/ Poolside porch | Balcony view

Island City House Hotel

Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary

Troy

AED 708 total

includes taxes & fees

15 Jun - 16 Jun

L'Habitation Guest House

Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary

Richard

AED 522 total

includes taxes & fees

15 Jun - 16 Jun

Marrero's Guest Mansion

Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary

Robert

AED 946 total

includes taxes & fees

13 Jul - 14 Jul

Superior Studio Suite, 1 King Bed with Sofa bed, Accessible, Refrigerator & Microwave | Free WiFi, bed sheets

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary

Annette

AED 887 total

includes taxes & fees

14 Jun - 15 Jun

The Grand Guesthouse

Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary

Duncan

AED 615 total

includes taxes & fees

18 Jun - 19 Jun

Heron House - Adult Only

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

Renee Louise

AED 658 total

includes taxes & fees

16 Jun - 17 Jun

Santa Maria Suites

Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary

Steven

AED 1,525 total

includes taxes & fees

21 Jun - 22 Jun

Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers

Ella's Cottages - Key West Historic Inns

Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary

Nanci

AED 962 total

includes taxes & fees

29 Jun - 30 Jun

3 outdoor pools, a heated pool, sun loungers

Ambrosia Key West

Old Town Key West, 1 km from Florida Keys National Marine Sanctuary

Lori

AED 738 total

includes taxes & fees

15 Jun - 16 Jun

Westwinds Inn

Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary

michael

AED 762 total

includes taxes & fees

15 Jun - 16 Jun

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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property	Property class	Guest rating
Almond Tree Inn Hotel - Adults Only	3.5 star property	10.0 Exceptional 1,016 reviews	View
Key West Villas	3.5 star property	9.8 Exceptional 262 reviews	View
The Gardens Hotel	4.0 star property	9.8 Exceptional 1,007 reviews	View
Orchid Key Inn - Adults Only	3.5 star property	9.8 Exceptional 1,012 reviews	View
Simonton Court Historic Inn & Cottages	2.5 star property	9.8 Exceptional 982 reviews	View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Heron House - Adult Only

10/10 Excellent

"Perfect and quiet escape just off of duval. Walking distance from all the main places. We will definitely be back!"

Coco Plum Inn

8/10 Good

"For the most part, it was very clean. Rooms were well kept up with the pool area is absolutely magical very beautiful. The breakfast in the morning is very cute and romantic. Only downside to our stay is the plumbing was not great three out of the six days we were there we had to go around the corner to a bar to go to the bathroom because the toilet wouldn’t flush, but that’s the only flaw everything else was beautiful my husband and I loved it. I will return and if you’re looking for AC, they have the coldest rooms and it’s so refreshing after a hot day and the hotel manager is so awesome and so friendly."

Duval House

10/10 Excellent

"Loved our stay here. Upon arrival we were offered complimentary drinks and check in was a breeze. Our room was so coxy and clean. The grounds were like being in a tropical Paradise! Everything was perfect. Right on Duvall Street and we walked everywhere. Plenty of restsurants and bars. We tried several restaurants, but our fav was Havana Island Cafe (I think). Had to enter through an alley. It was a food truck with a bar and the BEST food. Highly recommend!! We did the hop on/hop off tour our 1st full day and I wished we had just rented a golf cart, which we did for the remainder of our trip. Breakfast was awesome. The best waffles and the staff were so nice. It was a bucket list trip for me and I was not disappointed. Everyone should visit Key West and stay at the Duval House!!!"

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

4.4/5 (128 reviews)

You can spend an afternoon studying the exhibits at Florida Keys Eco - Discovery Center during your travels in Key West. Discover the area's lively bars and its lively festivals.

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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?

Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1535 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Florida Keys National Marine Sanctuary?

Adjacent to Florida Keys National Marine Sanctuary, Caribbean House is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and private balconies. Other good choices close by include La Concha Key West, Autograph Collection and Southernmost Beach Resort and Guesthouses.

How many hotels will I be able to find near Florida Keys National Marine Sanctuary?

Expedia has 1535 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.

If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?

Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.

Where can I learn more about changing or cancelling my trip in the area near Florida Keys National Marine Sanctuary?

To find more details about updating your stay near Florida Keys National Marine Sanctuary or cancelling it, head over to our customer service page.

What can I see and do near Florida Keys National Marine Sanctuary?

Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Key West Film Society, and Red Barn Theater if you're interested in local theater.

Find hotels near Florida Keys National Marine Sanctuary, Key West from AED 522

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Our top choices for Florida Keys National Marine Sanctuary hotels

Almond Tree Inn Hotel - Adults Only

Key West Villas

The Gardens Hotel

Orchid Key Inn - Adults Only

Simonton Court Historic Inn & Cottages

The Conch House Heritage Inn

The Marquesa Hotel

Tropical Inn

Douglas House - Adults Only

Weatherstation Inn

Island City House Hotel

L'Habitation Guest House

Marrero's Guest Mansion

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

The Grand Guesthouse

Heron House - Adult Only

Santa Maria Suites

Ella's Cottages - Key West Historic Inns

Ambrosia Key West

Westwinds Inn

Compare popular hotels close to Florida Keys National Marine Sanctuary

Top Florida Keys National Marine Sanctuary Hotel Reviews

Heron House - Adult Only

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

Frequently asked questions

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Hotels near popular Key West Attractions

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