The Best Hotels Closest to Florida Keys National Marine Sanctuary in Key West for 2026

Our top choices for Florida Keys National Marine Sanctuary hotels

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Almond Tree Inn Hotel - Adults Only

Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary

Jimmy

AED 911 total

includes taxes & fees

16 Jun - 17 Jun

Orchid Key Inn - Adults Only

Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary

Michael

AED 884 total

includes taxes & fees

16 Jun - 17 Jun

Key West Villas

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Jennifer

AED 852 total

includes taxes & fees

11 Jun - 12 Jun

Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished

Simonton Court Historic Inn & Cottages

Historic Seaport, 1 km from Florida Keys National Marine Sanctuary

Olha

AED 667 total

includes taxes & fees

21 Jun - 22 Jun

The Gardens Hotel

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Joseph

AED 988 total

includes taxes & fees

28 Jun - 29 Jun

The Marquesa Hotel

Old Town Key West, 1 km from Florida Keys National Marine Sanctuary

Julian

AED 1,483 total

includes taxes & fees

11 Jun - 12 Jun

The Conch House Heritage Inn

Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary

Lucy

AED 982 total

includes taxes & fees

14 Jun - 15 Jun

Douglas House - Adults Only

Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary

Matthew

AED 566 total

includes taxes & fees

15 Jun - 16 Jun

11 Gecko's Garden - Adults Only | Premium bedding, pillowtop beds, individually decorated

Tropical Inn

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

Akhenaton

AED 658 total

includes taxes & fees

11 Jun - 12 Jun

Deluxe Suite, 1 King Bed, Private Pool | View from room

H2O Suites - Adults Only

Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary

Elizabeth

AED 1,607 total

includes taxes & fees

21 Jun - 22 Jun

Premium bedding, iron/ironing board, free WiFi, bed sheets

Weatherstation Inn

Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary

A. Elise

AED 781 total

includes taxes & fees

15 Jun - 16 Jun

Coco Plum Inn

Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary

Brinkley

AED 781 total

includes taxes & fees

6 Jul - 7 Jul

Cigar House King Suite w/ Poolside porch | Balcony view

Island City House Hotel

Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary

Troy

AED 708 total

includes taxes & fees

14 Jun - 15 Jun

Duval House

Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary

gerald

AED 633 total

includes taxes & fees

16 Jun - 17 Jun

L'Habitation Guest House

Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary

Amy

AED 554 total

includes taxes & fees

15 Jun - 16 Jun

Marrero's Guest Mansion

Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary

Robert

AED 988 total

includes taxes & fees

29 Jun - 30 Jun

Superior Studio Suite, 1 King Bed with Sofa bed, Accessible, Refrigerator & Microwave | Free WiFi, bed sheets

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary

Annette

AED 659 total

includes taxes & fees

11 Jun - 12 Jun

Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers

Ella's Cottages - Key West Historic Inns

Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary

Nanci

AED 936 total

includes taxes & fees

11 Jun - 12 Jun

Santa Maria Suites

Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary

Jill

AED 1,525 total

includes taxes & fees

21 Jun - 22 Jun

Southernmost House - Adult Exclusive

Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary

BOBBY J.

AED 1,255 total

includes taxes & fees

23 Jun - 24 Jun

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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property	Property class	Guest rating
Almond Tree Inn Hotel - Adults Only	3.5 star property	10.0 Exceptional 1,011 reviews	View
Orchid Key Inn - Adults Only	3.5 star property	9.8 Exceptional 1,009 reviews	View
Key West Villas	3.5 star property	9.8 Exceptional 262 reviews	View
Simonton Court Historic Inn & Cottages	2.5 star property	9.8 Exceptional 978 reviews	View
The Gardens Hotel	4.0 star property	9.8 Exceptional 1,006 reviews	View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Douglas House - Adults Only

10/10 Excellent

"Great location great room"

Wicker Guesthouse

4/10 Poor

"I had a room that was back down an outdoor walkway that flooded with about 8 in a of water and there was no other way to the room.I made note with the office and they were not very responsive. I feel the room was a fire has hard because you only had the one way out. Multiply plug in strips in the room with various things plugged in. I was a single traveler, as a single person, don’t let them put you in 208 and forget about you."

La Concha Key West, Autograph Collection

6/10 Okay

"The hotel is in a great location. There were a few issues: I booked a king room But they gave us 2 queen beds plus the internet never worked so no streaming Netflix, prime or tv. They sent engineers to our room several times but never got it to work. I wish there was a hot tub but there isn’t and there are no ice machines, you have to ask front desk for ice whenever needed."

Heron House - Adult Only

8/10 Good

"The property was gorgeous and peaceful. It was close to all of the action, but totally quiet once you turned the corner into Heron House. Breakfast was personally just like I eat at home, so I was happy with everything provided. My room was unbelievable. It was gorgeous and spacious. There was plenty of space for belongings. The air condition was as perfect as it comes, and the room was always nice and cool. I appreciated that there was a functioning sink placed as a kitchenette outside of the bathroom. Now, the downside: all of the plumbing except for the toilet was terrible. There were lightbulbs in the room that needed changing. The lightbulb inside the closet was burned out, but needed to find things. The lamp by the bed was loose from the wall, and the lampshade kept falling off. I think the owners need to do a walk-through and check out these things. That said and done, I would return to Heron House in a heartbeat."

Pegasus International Hotel

10/10 Excellent

"Very clean, nice breakfast, clean pool, quiet outdoor shaded area to chill out. Wonderful Natalia and the rest of the staff were very kind and considerate of every need. There was a guest asked to leave and fined for smoking on the property. THEY DON"T ALLOW DISRESPECTFUL CLIENTS! Stay with Natalia and you will have a great time. "

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

4.4/5 (128 reviews)

You can spend an afternoon studying the exhibits at Florida Keys Eco - Discovery Center during your travels in Key West. Discover the area's lively bars and its lively festivals.

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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?

Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1535 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Florida Keys National Marine Sanctuary?

Adjacent to Florida Keys National Marine Sanctuary, Caribbean House is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and private balconies. Other good choices close by include La Concha Key West, Autograph Collection and Southernmost Beach Resort and Guesthouses.

How many hotels will I be able to find near Florida Keys National Marine Sanctuary?

Expedia has 1535 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.

If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?

Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.

Where can I learn more about changing or cancelling my trip in the area near Florida Keys National Marine Sanctuary?

To find more details about updating your stay near Florida Keys National Marine Sanctuary or cancelling it, head over to our customer service page.

What can I see and do near Florida Keys National Marine Sanctuary?

Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Key West Film Society, and Red Barn Theater if you're interested in local theater.

Find hotels near Florida Keys National Marine Sanctuary, Key West from AED 554

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Our top choices for Florida Keys National Marine Sanctuary hotels

Almond Tree Inn Hotel - Adults Only

Orchid Key Inn - Adults Only

Key West Villas

Simonton Court Historic Inn & Cottages

The Gardens Hotel

The Marquesa Hotel

The Conch House Heritage Inn

Douglas House - Adults Only

Tropical Inn

H2O Suites - Adults Only

Weatherstation Inn

Coco Plum Inn

Island City House Hotel

Duval House

L'Habitation Guest House

Marrero's Guest Mansion

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Ella's Cottages - Key West Historic Inns

Santa Maria Suites

Southernmost House - Adult Exclusive

Compare popular hotels close to Florida Keys National Marine Sanctuary

Top Florida Keys National Marine Sanctuary Hotel Reviews

Douglas House - Adults Only

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

Frequently asked questions

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Hotels near popular Key West Attractions

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