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Find Resorts & Hotels with Spas in Granite City, IL

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Check availability on Granite City Resorts & Hotels with Spas

Our top choices for Granite City hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1004)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is AED 559
AED 714 total
includes taxes & fees
15 Dec - 16 Dec
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1499)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is AED 493
AED 594 total
includes taxes & fees
21 Dec - 22 Dec
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1002)
"Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. "
United States
Lynne
The price is AED 1,524
AED 1,782 total
includes taxes & fees
1 Jan - 2 January 2026
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is AED 1,833
AED 2,139 total
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Granite City Hotel Reviews

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

10/10 Excellent
"Great stay in downtown St. Louis. Easy access to most areas downtown"
Vusani 2-night trip
Posted 4 days ago
Embassy Suites by Hilton St. Louis Downtown

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Frequently asked questions

Looking for a spa hotel in Granite City?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the historical sites and shopping in Granite City—your day trip starts here. Enjoy the lakeside setting during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Granite City?
Experience Granite City and visit Cahokia Mounds State Historic Site, Mississippi River, and Missouri River. If you have extra time while you're in the area, you might want to stop by Horseshoe Lake State Park and Six Mile Regional Library District - Johnson Road.
What is a Granite City spa hotel?
Spa hotels in Granite City provide lodging and have an on-site spa offering services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.