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Vacation Homes in Greene County

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Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Top Cities in Greene County

A brick-paved street with a gazebo, a red car, and a white pickup truck.
Vacation HomesVacation Homes

Jefferson

Jefferson

Our top choices for Greene County vacation homes

A two-story house with a front porch, a garage, and a small shed.

1. 1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks

1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks
Boone
10.0 out of 10, Exceptional, (78 reviews)
"Very peaceful and relaxing!"
United States
Matthew M.
The price is AED 711
AED 911 total
includes taxes & fees
1 Nov - 2 Nov
1800s Home, Train-Themed Decor, Walk to Downtown & Attractions, Exclusive Perks
A kitchen with a granite countertop, wooden cabinets, and a large window.

2. Large home on golf course, close to Seven Oaks, Ledges Park & ISU. Sleeps 12+

Large home on golf course, close to Seven Oaks, Ledges Park & ISU. Sleeps 12+
Boone
9.4 out of 10, Exceptional, (50 reviews)
"Large house, good location, responsive host!"
United States
Ryan J.
Large home on golf course, close to Seven Oaks, Ledges Park & ISU. Sleeps 12+
A view from a window overlooking a river and fields during sunset.

3. Private Barndo with Hot Tub, fireplace & pits. Waterfront views. Lots of games.

Private Barndo with Hot Tub, fireplace & pits. Waterfront views. Lots of games.
Glidden
10.0 out of 10, Exceptional, (3 reviews)
"We had an amazing time. If you want a place secluded with activities to keep you busy this is the place. Very clean and a lot of hang out space. Plenty of bathrooms which is always great with group of people. Would definitely recommend for anyone looking for a place to stay near the area."
United States
Ellen W.
Private Barndo with Hot Tub, fireplace & pits. Waterfront views. Lots of games.
Living area

4. Charming 2-bedroom building with AC, fitness room in the country south of Boone

Charming 2-bedroom building with AC, fitness room in the country south of Boone
Boone
7.4 out of 10, Good, (3 reviews)
"We had everything we needed! Hosts were very responsive to any questions."
United States
Blythe W.
Charming 2-bedroom building with AC, fitness room in the country south of Boone
A modern kitchen with a long island counter, black cabinets, and a stainless steel refrigerator.

5. Spacious 5-bedroom house in charming Breda with AC comfort

Spacious 5-bedroom house in charming Breda with AC comfort
Breda
Spacious 5-bedroom house in charming Breda with AC comfort
A spacious living room with hardwood floors, a chandelier, a dining table with chairs, and a sofa.

6. Natural Nesting Grounds - Boone, IA

Natural Nesting Grounds - Boone, IA
Boone
9.8 out of 10, Exceptional, (36 reviews)
"Beautiful property. Owner was VERY accommodating to this first time VBRO user."
United States
Kelli A.
Natural Nesting Grounds - Boone, IA
A compact kitchen with a stove, oven, and refrigerator, a dining table with chairs, and a potted plant.

7. Natural Nook - Boone, IA

Natural Nook - Boone, IA
Boone
9.4 out of 10, Exceptional, (3 reviews)
"This stay was just perfect!"
United States
Marcia O.
Natural Nook - Boone, IA
A kitchen with dark wooden cabinets, a built-in oven, and a countertop with a kettle and other appliances.

8. 4BR-2BA, Sleeps 8 | High Trestle Trail

4BR-2BA, Sleeps 8 | High Trestle Trail
Madrid
10.0 out of 10, Exceptional, (2 reviews)
"Beautiful property overlooking an unspoiled nature area in the back of the house. We enjoyed taking walks and having coffee on the deck! Very close to the High Trestle Trail and Bridge— a beautiful place to go for a walk or bike ride!House was clean, very comfortable, and had great features. Loved the cozy beds, vintage decor accents, spacious gathering spaces, and beautiful sunny kitchen. Perfect for families. Hope to go back when in the area again with extended family!"
United States
Noelle E.
4BR-2BA, Sleeps 8 | High Trestle Trail
A kitchen with wooden cabinets, a stainless steel oven, and a dining table with chairs.

9. Railroad themed 3-bedroom house in Boone The Main Street Station is pet friendly

Railroad themed 3-bedroom house in Boone The Main Street Station is pet friendly
Boone
10.0 out of 10, Exceptional, (15 reviews)
"Great place! Thanks for a wonderful stay."
United States
Rebecca
The price is AED 1,139
AED 1,929 total
includes taxes & fees
1 Nov - 2 Nov
Railroad themed 3-bedroom house in Boone The Main Street Station is pet friendly
A house entrance with a wooden door, a potted plant, and a brick pathway.

10. Rest in charming Perry

Rest in charming Perry
Perry
Rest in charming Perry
A patio with a table and chairs, string lights, a barbecue grill, and hanging plants.

11. Historic Home in the Heart of Perry

Historic Home in the Heart of Perry
Perry
10.0 out of 10, Exceptional, (44 reviews)
"Grandma Helen’s was an absolute gem!! Extraordinary home in a small town atmosphere. Stayed here to take in the great bicycle trail system in the area."
United States
Debra K. B.
Historic Home in the Heart of Perry
A spacious living room with a wooden ceiling, a fireplace, and blue upholstered seating.

12. 8 Mi to Lake Panorama: Cozy Family Getaway

8 Mi to Lake Panorama: Cozy Family Getaway
Guthrie Center
4.0 out of 10, (1 review)
"We were excited to stay at this property given our trip and reason we were in town.Upon arrival, most of the house was unclean. There was dust, bugs, and debris in most rooms. This includes in the beds and on the bedding for 2 of the beds.Two of the beds were absolutely rock hard and one fell through the frame.The layout of the house was interesting and fun, however it did not live up to the pictures in the listing.The property owner was extremely responsive and quick to respond to any questions...
United States
Tanner B.
8 Mi to Lake Panorama: Cozy Family Getaway
A modern kitchen with a large island, white cabinetry, and a built-in oven.

13. The peaceful oasis Charming 3-bedroom house with WiFi, AC in welcoming Carroll

The peaceful oasis Charming 3-bedroom house with WiFi, AC in welcoming Carroll
Carroll
8.4 out of 10, Very good, (8 reviews)
"It was very family friendly"
United States
Louis
The peaceful oasis Charming 3-bedroom house with WiFi, AC in welcoming Carroll
A modern kitchen with white cabinets, a wooden countertop, a microwave, a stove, and a refrigerator.

14. Sleeps 6. Pets welcome. Wi-Fi. 3 bedroom house

Sleeps 6. Pets welcome. Wi-Fi. 3 bedroom house
Jefferson
9.2 out of 10, Wonderful, (25 reviews)
"Location was perfect! Great bang for you buck. I'd stay there again."
United States
Anonymous traveler
The price is AED 413
AED 850 total
includes taxes & fees
31 Oct - 1 Nov
Sleeps 6. Pets welcome. Wi-Fi. 3 bedroom house
A wooden deck with lounge chairs and a covered area with umbrellas, overlooking a calm lake with boats and greenery in the background.

15. Scenic treetop views at Lake Panorama

Scenic treetop views at Lake Panorama
Panora
9.4 out of 10, Exceptional, (9 reviews)
"Great property"
United States
Mark B.
Scenic treetop views at Lake Panorama
A two-story house with a front porch and a garage.

16. Nature Lover’s Retreat By the High Trestle Trail!

Nature Lover’s Retreat By the High Trestle Trail!
Woodward
10.0 out of 10, Exceptional, (2 reviews)
"Great location to ride on the High Trestle Trail."
United States
Laura W.
Nature Lover’s Retreat By the High Trestle Trail!
A wooden cabin bathroom with a large bathtub, a fireplace, and a window with a view of greenery.

17. Timberpine Lodge - Escape to the Country

Timberpine Lodge - Escape to the Country
Adel
10.0 out of 10, Exceptional, (33 reviews)
"We had a wonderful family get away here. Especially loved the screened in porch having morning coffee. Beautiful location and the cabin was spacious, with a large kitchen, and plenty of space for our large family to hang out. I would highly recommend this property!"
United States
Dave K.
Timberpine Lodge - Escape to the Country
A kitchen with white cabinets, a granite countertop, a wooden floor, and a built-in oven.

18. A GREAT 4 Bedroom 2 Bath home with lots of room for fun It's The American Dream!

A GREAT 4 Bedroom 2 Bath home with lots of room for fun It's The American Dream!
Boone
10.0 out of 10, Exceptional, (9 reviews)
"Great place & owners were awesome to work with."
United States
Beth C.
The price is AED 1,286
AED 2,114 total
includes taxes & fees
2 Nov - 3 Nov
A GREAT 4 Bedroom 2 Bath home with lots of room for fun It's The American Dream!
A kitchen with white cabinets, a stainless steel microwave, an oven, a dishwasher, and a window with blinds.

19. Retro themed 2-bedroom house in Boone The Retro Rambler is pet friendly!

Retro themed 2-bedroom house in Boone The Retro Rambler is pet friendly!
Boone
10.0 out of 10, Exceptional, (15 reviews)
"Perfect house for my trip! I loved the 60’s 70’s theme throughout. Perfect space for me and my pup. Nice neighborhood, easy in and out. Loved the place!"
United States
Julie J.
Retro themed 2-bedroom house in Boone The Retro Rambler is pet friendly!
A residential street with houses, a driveway, and a tree.

20. Half-Mi to High Trestle Trail! Iowa Adventure Base

Half-Mi to High Trestle Trail! Iowa Adventure Base
Woodward
10.0 out of 10, Exceptional, (1 review)
"Was a perfect spot to access the biking trail!"
United States
Anonymous traveler
Half-Mi to High Trestle Trail! Iowa Adventure Base
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Greene County Hotel Reviews

Cobblestone Inn & Suites - Boone

Cobblestone Inn & Suites - Boone

10/10 Excellent
"Very nice stay"
William 1-night trip
Posted 1 day ago
Cobblestone Inn & Suites - Boone

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