Find Resorts & Hotels with Spas in Lower Keys, FL

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Lower Keys Resorts & Hotels with Spas

Next weekend
In two weeks

Our top choices for Lower Keys hotels with a spa

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.4 out of 10, Very Good, (615 reviews)
  • cleanliness
    Beach resort with spa offering aromatherapy, Ayurvedic treatments, and beachside massages for ultimate relaxation.
The price is AED 1,337
AED 1,752 total
includes taxes & fees
23 Apr - 24 Apr
Casa Marina Key West, Curio Collection by Hilton

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Rejuvenate your spirit at this waterfront sanctuary where serene spa treatments complement 3 sparkling pools.
The price is AED 1,088
AED 1,463 total
includes taxes & fees
3 May - 4 May
Tranquility Bay Beachfront Hotel and Resort

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (1,005 reviews)
  • cleanliness
    Luxurious beachfront spa retreat offers deep-tissue massages and serene outdoor treatments in Key West.
The price is AED 973
AED 1,343 total
includes taxes & fees
3 May - 4 May
The Reach Key West, Curio Collection by Hilton

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Luxurious oceanfront escape with 3 spa treatment rooms offers deep-tissue massages, facials, and holistic therapies for pure rejuvenation.
The price is AED 1,120
AED 1,517 total
includes taxes & fees
12 May - 13 May
Hyatt Centric Key West Resort and Spa

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Waterfront resort spa with exotic massage options and ocean views offers full-service relaxation by the Key West sunset.
The price is AED 1,433
AED 1,897 total
includes taxes & fees
3 May - 4 May
Ocean Key Resort - A Noble House Resort

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,168 reviews)
  • cleanliness
    Rejuvenate at this waterfront resort's luxurious Ocean Spa with specialized massages in serene rooms.
The price is AED 901
AED 1,151 total
includes taxes & fees
6 May - 7 May
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,076 reviews)
  • cleanliness
    Indulge in oceanfront spa retreats with sunset views at this tropical Key West haven just steps from Duval Street.
The price is AED 988
AED 1,256 total
includes taxes & fees
3 May - 4 May
Opal Key Resort & Marina, Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.8 out of 10, Excellent, (3,218 reviews)
  • cleanliness
    Serene beachside spa oasis offers tropical relaxation with ocean views and couples treatments.
The price is AED 974
AED 1,365 total
includes taxes & fees
19 May - 20 May
Southernmost Beach Resort and Guesthouses

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,084 reviews)
  • cleanliness
    Waterfront spa resort invites relaxation with private beach, outdoor pool, and rejuvenating treatments in Key West's central locale.
The price is AED 1,760
AED 2,237 total
includes taxes & fees
26 Apr - 27 Apr
Pier House Resort & Spa

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,120 reviews)
  • cleanliness
    Restore serenity at this beachfront hotel with 5 tranquil spa treatment rooms and multiple outdoor pools overlooking stunning ocean views.
The price is AED 1,378
AED 1,791 total
includes taxes & fees
19 May - 20 May
Isla Bella Beach Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Lower Keys

Top Lower Keys Hotel Reviews

Explore a world of travel with Expedia