Find Resorts & Hotels with Spas in Mira Mesa, CA

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Check availability on Mira Mesa Resorts & Hotels with Spas

Our top choices for Mira Mesa hotels with a spa

Fitness studio
Sycuan Casino Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1631)
"Nice rooms. Great food at all restaurants "
United States
Steve
Sycuan Casino Resort
Hot stone massages, prenatal massages, sports massages, body scrubs
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is AED 432
AED 662 total
includes taxes & fees
14 Dec - 15 Dec
San Diego Mission Bay Resort
Body treatments, aromatherapy, body wraps, body scrubs, facials
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1859)
"Enjoyed my stay"
United States
Brandon
The price is AED 380
AED 621 total
includes taxes & fees
4 Jan - 5 January 2026
Hilton San Diego Bayfront
3 outdoor pools, cabanas (surcharge), pool umbrellas
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1570)
"Loved our stay "
United States
Jeremy
The price is AED 474
AED 739 total
includes taxes & fees
18 Dec - 19 Dec
Hyatt Regency Mission Bay Spa and Marina
Exterior
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
Point Loma
8.8 out of 10, Excellent, (1554)
"Every time i have stayed here everything is always clean...no complaints!"
United States
Joseline
The price is AED 420
AED 483 total
includes taxes & fees
4 Jan - 5 January 2026
Best Western Plus Island Palms Hotel & Marina
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
Sheraton Carlsbad Resort & Spa

Sheraton Carlsbad Resort & Spa

Sheraton Carlsbad Resort & Spa
4.0 star property
Carlsbad Ranch
8.2 out of 10, Very Good, (1001)
"Staff were excellent. Property is beautiful. "
United States
Andrea
The price is AED 621
AED 845 total
includes taxes & fees
14 Dec - 15 Dec
Sheraton Carlsbad Resort & Spa
Facials, 2 treatment rooms, massages
The Westin San Diego Bayview

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1061)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is AED 497
AED 682 total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview
Couples treatment rooms, sauna, hot tub, steam room, body treatments
Loews Coronado Bay Resort

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
Silver Strand
8.8 out of 10, Excellent, (1067)
"My stay was wonderful! "
United States
Jeanine
The price is AED 657
AED 908 total
includes taxes & fees
14 Dec - 15 Dec
Loews Coronado Bay Resort
Water view
Kona Kai San Diego

Kona Kai San Diego

Kona Kai San Diego
4.0 star property
Point Loma
8.2 out of 10, Very Good, (1000)
"had a wonderful time for our honey moon here "
United States
Anna
The price is AED 553
AED 856 total
includes taxes & fees
10 Jan - 11 January 2026
Kona Kai San Diego
Couples treatment rooms, body treatments, hot stone massages
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2947)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is AED 559
AED 642 total
includes taxes & fees
14 Dec - 15 Dec
Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mira Mesa Hotel Reviews

Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"excellent hotel pre-cruise. great appetizers at Happy Hour! Very nice room."
Patricia 1-night trip
Posted 2 days ago
Sheraton San Diego Resort

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Frequently asked questions

Looking for a spa hotel in Mira Mesa?
Forget the stress of everyday life and book yourself a hotel with a spa. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Mira Mesa?
Enjoy Mira Mesa and visit San Diego Zoo, Mission Bay, and Mission Beach. If you have spare time during your trip, you might want to make a stop at Port of San Diego and Petco Park.
What is a Mira Mesa spa hotel?
Spa hotels in Mira Mesa provide lodging and have an on-site spa offering services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.