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Check prices for these dates

Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec
In one month
9 Jan - 11 Jan
In two months
6 Feb - 8 Feb

B&B in O Brien

No exact matches found, but these alternatives could be just right

Recommended hotels in O Brien

Property grounds
Our Spring Getaway Is Across The Street From Royal Springs

Our Spring Getaway Is Across The Street From Royal Springs

O'Brien
10.0 out of 10, Exceptional, (2)
"Place is as described. Nice and clean. Large property plenty of room for parking."
United States
J S.
The price is AED 413
AED 730 total
includes taxes & fees
15 Dec - 16 Dec
Our Spring Getaway Is Across The Street From Royal Springs
Property grounds
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

O'Brien
9.4 out of 10, Exceptional, (59)
"We absolutely enjoyed our stay. We had 1 small issue that was quickly resolved by the host. The place was conveniently located close to royal spring and that boat ramp. The decks on this place was massive. The river deck was nice to sit on as well. We will definitely be back if they will have us."
United States
David M.
The price is AED 621
AED 1,440 total
includes taxes & fees
10 Dec - 11 Dec
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
Exterior
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1004)
"Great place for a restful night when traveling. "
United States
Peggy
The price is AED 320
AED 360 total
includes taxes & fees
4 Jan - 5 January 2026
Tru by Hilton Lake City
Lobby
Comfort Suites Lake City

Comfort Suites Lake City

2.5 star property
Lake City
9.6 out of 10, Exceptional, (1002)
"We love to stop here when traveling to Orlando"
United States
Bridget
The price is AED 378
AED 426 total
includes taxes & fees
10 Dec - 11 Dec
Comfort Suites Lake City
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1006)
"Staff was great and breakfast was awesome."
United States
Derrick
The price is AED 338
AED 380 total
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Lake City
Standard Cabin, 1 Queen Bed | Exterior
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

2.0 star property
High Springs
10.0 out of 10, Exceptional, (147)
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is AED 364
AED 562 total
includes taxes & fees
10 Dec - 11 Dec
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

2.5 star property
Alachua
9.4 out of 10, Exceptional, (472)
"Staff very helpful- clean updated facility. "
United States
bethany
The price is AED 350
AED 393 total
includes taxes & fees
1 Jan - 2 January 2026
Hampton Inn & Suites Alachua I-75
Lobby
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

2.0 star property
Lake City
8.0 out of 10, Very Good, (66)
"Great little motel with extremely nice staff. "
United States
Georgiy
The price is AED 192
AED 216 total
includes taxes & fees
10 Dec - 11 Dec
Motel 6 – Lake City, Fl – Medical Center
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

2.5 star property
Lake City
9.0 out of 10, Wonderful, (164)
"Very clean, friendly staff, safe and quiet "
United States
Amy
The price is AED 327
AED 368 total
includes taxes & fees
4 Jan - 5 January 2026
Fairfield Inn & Suites Lake City
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

2.5 star property
Lake City
9.4 out of 10, Exceptional, (1000)
"It was a great stay "
United States
Miranda
The price is AED 347
AED 390 total
includes taxes & fees
4 Jan - 5 January 2026
Hampton Inn & Suites Lake City
Free daily buffet breakfast
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

2.5 star property
Live Oak
8.4 out of 10, Very Good, (772)
"Have stayed here whenever we are in town. Always god stay."
United States
Gregg
The price is AED 426
AED 469 total
includes taxes & fees
4 Jan - 5 January 2026
Holiday Inn Express & Suites Live Oak by IHG
Exterior
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
Lake City
8.8 out of 10, Excellent, (1008)
"It was a great hotel! "
United States
Sarah
The price is AED 344
AED 387 total
includes taxes & fees
15 Dec - 16 Dec
La Quinta Inn & Suite by Wyndham Lake City
Exterior
Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City

2.0 star property
Lake City
7.2 out of 10, Good, (663)
"Nice stay"
United States
Kimberly
The price is AED 244
AED 274 total
includes taxes & fees
11 Dec - 12 Dec
Super 8 by Wyndham Lake City
Property amenity
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

3.0 star property
Lake City
9.6 out of 10, Exceptional, (175)
"Nice place for a weekend trip to the springs close by.Would definitely stay here again."
United States
Mary
The price is AED 393
AED 442 total
includes taxes & fees
21 Dec - 22 Dec
Courtyard By Marriott Lake City
Standard Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee

2.5 star property
Live Oak
7.2 out of 10, Good, (613)
"Clean rooms, very friendly staff"
United States
Kristin L
The price is AED 250
AED 275 total
includes taxes & fees
22 Dec - 23 Dec
Quality Inn White Springs Suwanee
Exterior
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

3.0 star property
Lake City
8.6 out of 10, Excellent, (1002)
"Dog friendly. "
United States
Barbara
The price is AED 305
AED 343 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn & Suites Lake City by IHG
Pillowtop beds, in-room safe, desk, blackout drapes
Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75

2.0 star property
Lake City
7.6 out of 10, Good, (1002)
"Clean room everything I could need staff very nice and helpful I ll be back "
United States
Daphnea
The price is AED 232
AED 261 total
includes taxes & fees
10 Dec - 11 Dec
Days Inn by Wyndham Lake City I-75
Iron/ironing board, free WiFi, bed sheets
Regal Inn

Regal Inn

2.5 star property
Lake City
8.6 out of 10, Excellent, (541)
"very clean room, A/C and heat work great, good TV, outstanding price, staff very friendly , next door to Waffle House, numerous Restaurants within 2 blocks ( walking ) , will be staying here more when traveling "
United States
Robert
The price is AED 228
AED 256 total
includes taxes & fees
10 Dec - 11 Dec
Regal Inn
Lobby
Econo Lodge Live Oak

Econo Lodge Live Oak

2.0 star property
Live Oak
7.0 out of 10, Good, (277)
"need grab bars"
United States
Frances and Edward
The price is AED 240
AED 264 total
includes taxes & fees
6 Jan - 7 January 2026
Econo Lodge Live Oak
BBQ/picnic area
Cindys Motel

Cindys Motel

2.5 star property
Mayo
9.0 out of 10, Wonderful, (127)
"Nice place"
Australia
Marie
Cindys Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O Brien Hotel Reviews

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

10/10 Excellent
"Steven and the rest of the staff here provided the best customer service. I will 100% stay here again. "
Zachariah 3-night trip
Posted 1 day ago
Motel 6 – Lake City, Fl – Medical Center

Frequently asked questions

Searching for B&Bs in O Brien?
If you want to find an accommodation with a small number of rooms and an intimate environment, a B&B might be the perfect option for your vacation to O Brien. When you want to explore some attractions in town, Suwannee River and Ichetucknee River are worth a stop.
Are you thinking about a B&B for your stay?
With attentive service, opportunities to socialize with other guests, and delectable breakfasts, B&Bs offer a truly one-of-a-kind setting.
When should I book my B&B in O Brien?
When you're dreaming of a stay in O Brien, year-round temperatures and rainfall may be important factors to consider. The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.
What is there to do in O Brien?
When you want to spend some time in the great outdoors, Suwannee River and Ichetucknee River are some notable spots. You might check out Ichetucknee Springs State Park if you have time to see more of the area.