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Find hotels in Otay Mesa West, San Diego from AED 254

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Discover 6,491 Otay Mesa West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1319)
"I always enjoy staying here "
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1004)
"Great place!"
The price is AED 407
AED 448 total
includes taxes & fees
22 Jun - 23 Jun
Days Inn by Wyndham San Diego-East/El Cajon

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.6 out of 10, Good, (1008)
"Good place for short stay"
The price is AED 327
AED 360 total
includes taxes & fees
19 Jun - 20 Jun
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1008)
"Great place very clean and nice staff!"
The price is AED 482
AED 530 total
includes taxes & fees
6 Jul - 7 Jul
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.4 out of 10, Exceptional, (352)
"Great spot for business travelers "
The price is AED 786
AED 866 total
includes taxes & fees
23 Jun - 24 Jun
SpringHill Suites by Marriott Chula Vista Eastlake

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1100)
"Great property, and customer service."
The price is AED 716
AED 789 total
includes taxes & fees
22 Jun - 23 Jun
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1011)
"Small rooms but friendly staff and prime location"
The price is AED 254
AED 281 total
includes taxes & fees
23 Jun - 24 Jun
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.2 out of 10, Wonderful, (1160)
"Nice place to stay "
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1443)
"Good service,nice breakfast "
The price is AED 465
AED 512 total
includes taxes & fees
29 Jun - 30 Jun
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1236)
"Had a very nice stay."
The price is AED 526
AED 578 total
includes taxes & fees
18 Jun - 19 Jun
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1079)
"Clean quiet and staff is friendly!"
The price is AED 305
AED 347 total
includes taxes & fees
19 Jun - 20 Jun
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1004)
"Affordable and near the border for convenience. "
Valli Hi Motel

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1094)
"We really enjoy this hotel, it was clean and the service was excellent."
The price is AED 449
AED 511 total
includes taxes & fees
25 Jun - 26 Jun
Best Western Americana Inn

Chula Vista Inn

2.5 star property
6.6 out of 10, (1003)
"Nice hotel "
Chula Vista Inn

Quality Inn San Diego South - Chula Vista

2.5 star property
7.8 out of 10, Good, (961)
"Close to freeway, restaurant and mall"
The price is AED 360
AED 396 total
includes taxes & fees
23 Jun - 24 Jun
Quality Inn San Diego South - Chula Vista

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1745)
"Had a really nice stay!!"
The price is AED 492
AED 542 total
includes taxes & fees
17 Jul - 18 Jul
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1193)
"Very nice staff and service "
The price is AED 471
AED 518 total
includes taxes & fees
18 Jun - 19 Jun
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1007)
"Enjoyed our stay"
The price is AED 338
AED 372 total
includes taxes & fees
24 Jun - 25 Jun
Howard Johnson by Wyndham National City/San Diego South

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.8 out of 10, Good, (1442)
"Very clean and good servive and good breakfast. Great location"
The price is AED 360
AED 397 total
includes taxes & fees
23 Jun - 24 Jun
SureStay Hotel by Best Western Chula Vista San Diego Bay

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (928)
"Was very clean staff was friendly "
The price is AED 380
AED 428 total
includes taxes & fees
18 Jun - 19 Jun
Berkshire Motor Hotel
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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Mission Beach map

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach map

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Gaslamp Quarter map

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Ocean Beach, you won't get bored spending a day wandering around this part of San Diego.

Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighborhood that travelers like for its cathedral.

How many hotels can I expect to find in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodations in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.

Where can I learn more about changing or cancelling my trip to Otay Mesa West?

To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.

What is there to do around this San Diego neighborhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.