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Check prices for these dates

Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov
In one month
11 Dec - 13 Dec
In two months
8 Jan - 10 Jan

Our top choices for San Ysidro aparthotels

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

1. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (246 reviews)
"Excellent location, near little Italy, zoo and airport. Be aware that you are near airport so expect more noise than normal"
United States
Willie
The price is AED 426
AED 605 total
includes taxes & fees
29 Nov - 30 Nov
City24 Hotel Little Italy Mission Hills
A spacious lounge area with a sofa, a coffee table, and a bar with stools.

2. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,271 reviews)
"Nice accommodations"
United States
Michael
The price is AED 529
AED 613 total
includes taxes & fees
30 Nov - 1 Dec
Marriott Vacation Club®, San Diego
A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

3. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (523 reviews)
"Front desk service was amazing and love the central location to all the LGBTQ bars and restaurants."
United States
Victor
The price is AED 331
AED 373 total
includes taxes & fees
30 Nov - 1 Dec
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
A modern lobby with a green sofa, a wooden accent wall, and a large plant.

4. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (420 reviews)
"clean, affordable, safe, such a great stay!"
United States
Beatriz
The price is AED 359
AED 416 total
includes taxes & fees
16 Nov - 17 Nov
Little Italy Inn - Limited Service Apart Hotel
A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

5. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (242 reviews)
"Wonderful place!"
Canada
Eric
The price is AED 359
AED 409 total
includes taxes & fees
16 Nov - 17 Nov
Kasa Gaslamp Quarter San Diego
A modern bedroom with a bed, bedside table, lamp, and a mirror.

6. The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!

The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!
Downtown San Diego
The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!
A modern hotel room with a bed, a sofa, a coffee table, and a TV displaying the Netflix logo.

7. The Penn Hotel - Walk to Attractions & Sleeps 5!!

The Penn Hotel - Walk to Attractions & Sleeps 5!!
Downtown San Diego
The Penn Hotel - Walk to Attractions & Sleeps 5!!
🏙 Bright open-concept living residence—bathed in natural light with views overlooking the vibrant Gaslamp Quarter.

8. The Penn Hotel - Designer 2BR Near Gaslamp & Park

The Penn Hotel - Designer 2BR Near Gaslamp & Park
Downtown San Diego
The Penn Hotel - Designer 2BR Near Gaslamp & Park
A modern living room with a dining area, a flat-screen TV mounted on the wall, a sofa, and a bed.

9. The Penn Hotel - Smart TV, AC & Downtown Location!

The Penn Hotel - Smart TV, AC & Downtown Location!
Downtown San Diego
The Penn Hotel - Smart TV, AC & Downtown Location!
A modern bedroom with a large bed, a city view through the window, and a round nightstand with a plant.

10. The Penn Hotel - Smart TV, King Bed & Walkability!

The Penn Hotel - Smart TV, King Bed & Walkability!
Downtown San Diego
The Penn Hotel - Smart TV, King Bed & Walkability!
A dining table set with white bowls, wine glasses, and a vase with flowers.

11. The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!

The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!
Downtown San Diego
The price is AED 253
AED 1,156 total
includes taxes & fees
16 Nov - 17 Nov
The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!
☕ Gourmet kitchen detail—featuring sleek cabinetry, stainless microwave, and under-cabinet lighting.

12. The Penn Hotel - King & Queen Bed | Gaslamp Life

The Penn Hotel - King & Queen Bed | Gaslamp Life
Downtown San Diego
The Penn Hotel - King & Queen Bed | Gaslamp Life
A modern kitchen with a central island, stainless steel appliances, and a view of a cityscape through the window.

13. The Penn Hotel - Smart TV, AC & Gaslamp Steps Away

The Penn Hotel - Smart TV, AC & Gaslamp Steps Away
Downtown San Diego
The Penn Hotel - Smart TV, AC & Gaslamp Steps Away
🛋 Sunlit lounge area—thoughtfully arranged with armchairs and large windows for relaxing or taking in city views.

14. The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!

The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!
Downtown San Diego
The price is AED 253
AED 1,156 total
includes taxes & fees
16 Nov - 17 Nov
The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!
A rooftop pool with lounge chairs and a city skyline in the background.

15. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (567 reviews)
"Super nice amenities - would stay again. Great location"
United States
Nirmeen
The price is AED 662
AED 1,038 total
includes taxes & fees
15 Nov - 16 Nov
Kasa Little Italy San Diego
A modern kitchen with a central island, bar stools, a sofa, and a dining area with blue chairs.

16. The Penn Hotel -Live Above Gaslamp Nightlife &AC

The Penn Hotel -Live Above Gaslamp Nightlife &AC
Downtown San Diego
The Penn Hotel -Live Above Gaslamp Nightlife &AC
A modern hotel room with a bed, seating area, TV, and a dining table.

17. The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!

The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!
Downtown San Diego
The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!
A modern apartment with a kitchen island, seating area, and a bedroom with a large bed and a round mirror.

18. The Penn Hotel - Premium Beds & Gaslamp Nightlife!

The Penn Hotel - Premium Beds & Gaslamp Nightlife!
Downtown San Diego
The Penn Hotel - Premium Beds & Gaslamp Nightlife!
A dining area with a round table set for four, surrounded by dark chairs.

19. The Penn Hotel - Steps to Gaslamp & Petco Park, AC

The Penn Hotel - Steps to Gaslamp & Petco Park, AC
Downtown San Diego
The price is AED 253
AED 1,204 total
includes taxes & fees
18 Nov - 19 Nov
The Penn Hotel - Steps to Gaslamp & Petco Park, AC
A modern hotel room with a bed, a sofa, a dining table, and a large window offering a city view.

20. The Penn Hotel - King Bed, AC & Gaslamp Nightlife!

The Penn Hotel - King Bed, AC & Gaslamp Nightlife!
Downtown San Diego
The price is AED 253
AED 1,204 total
includes taxes & fees
17 Nov - 18 Nov
The Penn Hotel - King Bed, AC & Gaslamp Nightlife!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about San Ysidro

The world's busiest land border crossing transforms into a shopper's paradise at Las Americas Premium Outlets. Visit Border Field State Park for coastal trails where you can glimpse both San Diego and Tijuana from one stunning viewpoint.

See all hotels in San Ysidro
A beach with seagulls and a large metal fence.

Top reviews in San Ysidro

A spacious lounge area with a sofa, a coffee table, and a bar with stools.
Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
Downtown San Diego

10/10 Excellent

Nice property, good rooms, but the area around it is infested with homeless people and drug addicted people, unsafe.
United States
Aibek
Reviewed January 14, 2023
Marriott Vacation Club®, San Diego

Frequently Asked Questions

What can I look forward to during my San Ysidro aparthotel stay?

When you choose an aparthotel or serviced apartment in San Ysidro, expect to be more centrally situated. Take time to enjoy the array of shops and top-notch restaurants in this relaxing area. San Ysidro is also known for its beaches and live music.

What are the favorite aparthotels for my stay in San Ysidro?

Located 13.3 mi (21.4 km) from San Ysidro, Marriott Vacation Club®, San Diego is a favorite aparthotel featuring 264 apartments with free WiFi and comfy beds as well as hotel amenities like a restaurant. In the area, a couple of other top aparthotels to consider are Little Italy Inn - Limited Service Apart Hotel and Uptown Inn by Vantaggio - Limited Service Apart-Hotel.

How many aparthotels will I find in San Ysidro?

Bookable on Expedia, there are 14 hotels and other accommodations in San Ysidro. Though you won't find many aparthotels, we can help you find places to stay that are similar such as a condo or apartment.

What are the must-see places to visit in San Ysidro?

Favorite sights to visit while in town include San Ysidro Border Crossing. Explore the area and family-friendly sights such as San Diego Zoo, or get out into nature at a spot like Mission Bay. In the larger area, you’ll find popular places like Petco Park and Port of San Diego.

What is an aparthotel?

An aparthotel is both a hotel and an apartment, with amenities you might expect at a traditional hotel, and the space and privacy of an apartment. Feel like a local in an apartment-like space, often situated in the center of San Ysidro. Enjoy making home-cooked meals in a fully-equipped kitchen and having some extra space to relax after a long day of sightseeing.

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