Find hotels near Santo Spirito Hospital, Rome from AED 379

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Our top choices for Santo Spirito Hospital hotels

San Pietro Boutique Rooms

San Pietro Boutique Rooms
Prati, 0.6 km from Santo Spirito Hospital
10.0 out of 10, Exceptional, (915)
"Great place to stay in Rome. Quiet and less crowded. "
United States
Tanya
San Pietro Boutique Rooms

Passpartout Boutique Palace

Passpartout Boutique Palace
0.4 km from Santo Spirito Hospital
9.8 out of 10, Exceptional, (245)
"Excellent location, great dining options nearby, modern boutique hotel."
Canada
Matthew
The price is AED 458
AED 564 total
includes taxes & fees
13 Jan - 14 January 2026
Passpartout Boutique Palace

Navona Street Hotel

Navona Street Hotel
3.0 star property
0.4 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (269)
"Staff was very friendly and helpful. "
United States
Eli M
The price is AED 457
AED 555 total
includes taxes & fees
17 Dec - 18 Dec
Navona Street Hotel

Charme 308

Charme 308
0.3 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (95)
"Great location! The room was spotless. We loved everything about this place."
United States
Heather
The price is AED 513
AED 625 total
includes taxes & fees
16 Dec - 17 Dec
Charme 308

Cassiodoro 19

Cassiodoro 19
Prati, 0.7 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (524)
"Great stay"
United States
Robert
The price is AED 495
AED 596 total
includes taxes & fees
6 Jan - 7 January 2026
Cassiodoro 19

Le Suite Del Barone

Le Suite Del Barone
0.6 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (416)
"We enjoyed our stay very much. "
Germany
Ulrike
The price is AED 444
AED 548 total
includes taxes & fees
18 Dec - 19 Dec
Le Suite Del Barone

Passepartout

Passepartout
Parione, 0.6 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (286)
"Kind and helpful and in a great place. It was in the best spot to see every thing I wanted. Perfect for walking to grocery and shopping and restaurants "
United States
Catriona
Passepartout

Eccelso Hotel

Eccelso Hotel
3.0 star property
Prati, 0.8 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (205)
"Great place, great service, great location! highly recommended"
Canada
Jensen
The price is AED 336
AED 421 total
includes taxes & fees
21 Dec - 22 Dec
Eccelso Hotel

Horti 14 Borgo Trastevere Hotel

Horti 14 Borgo Trastevere Hotel
4.0 star property
0.7 km from Santo Spirito Hospital
9.6 out of 10, Exceptional, (327)
"Great location, super helpful staff, comfortable bed and delicious breakfast with a wide variety of food. Would absolutely stay here again!"
United States
Gary
The price is AED 669
AED 800 total
includes taxes & fees
18 Dec - 19 Dec
Horti 14 Borgo Trastevere Hotel

Capricci Romani

Capricci Romani
0.4 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (361)
"Really enjoyed the location and staff. Breakfast was amazing. "
United States
Raquel
Capricci Romani

All’Orologio

All’Orologio
0.4 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (168)
"Very happy with my choice… staff were excellent communicators before and during my stay, loved the location. "
Canada
Andrew
All’Orologio

B&B At Your Place

B&B At Your Place
0.4 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (420)
"Lucca is very helpful and the place was clean and perfectly what we needed. "
United States
Jennifer
B&B At Your Place

B&B Rome River Inn

B&B Rome River Inn
0.4 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (506)
"Staff very helpful Good location Enjoyed stay"
Australia
Richard
The price is AED 739
AED 865 total
includes taxes & fees
20 Dec - 21 Dec
B&B Rome River Inn

Now Apartments

Now Apartments
0.6 km from Santo Spirito Hospital
9.4 out of 10, Exceptional, (58)
"Such a great apartment in a very cool spot, access to lots of restaurants and shopping. Really loved our stay and would revisit. "
Australia
Renee
The price is AED 706
AED 828 total
includes taxes & fees
16 Dec - 17 Dec
Now Apartments

Relais Giulia

Relais Giulia
0.3 km from Santo Spirito Hospital
9.2 out of 10, Wonderful, (489)
"Clean, convenient, comfortable, charming"
United States
Ray Don
The price is AED 297
AED 379 total
includes taxes & fees
21 Dec - 22 Dec
Relais Giulia

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World
5.0 star property
Trastevere, 0.2 km from Santo Spirito Hospital
9.2 out of 10, Wonderful, (935)
"Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!"
United Kingdom
debra jane
The price is AED 1,733
AED 1,992 total
includes taxes & fees
8 Jan - 9 January 2026
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Hotel della Conciliazione

Hotel della Conciliazione
4.0 star property
0.4 km from Santo Spirito Hospital
9.2 out of 10, Wonderful, (1003)
"Everything was wonderful about this hotel, rooms were clean, breakfast was good and the staff are very friendly"
United States
Jennifer Joy
The price is AED 564
AED 685 total
includes taxes & fees
14 Jan - 15 January 2026
Hotel della Conciliazione

Boutique Hotel Atelier '800

Boutique Hotel Atelier '800
2.0 star property
0.4 km from Santo Spirito Hospital
9.2 out of 10, Wonderful, (140)
"Staff was very helpful, very clean and organized place"
United States
Jose Rolando
Boutique Hotel Atelier '800

Hotel Indigo Rome - St. George by IHG

Hotel Indigo Rome - St. George by IHG
5.0 star property
0.4 km from Santo Spirito Hospital
9.2 out of 10, Wonderful, (770)
"Very nice place to stay, centrally located"
United States
SAMUEL PARRISH
The price is AED 749
AED 1,039 total
includes taxes & fees
10 Jan - 11 January 2026
Hotel Indigo Rome - St. George by IHG

Vatican Style

Vatican Style
0.5 km from Santo Spirito Hospital
9.2 out of 10, Wonderful, (849)
"Would definitely stay again when looking for close to Vatican location. "
United States
Kevin
The price is AED 400
AED 483 total
includes taxes & fees
13 Jan - 14 January 2026
Vatican Style
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santo Spirito Hospital Hotel Reviews

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Frequently asked questions

What's the area like around Santo Spirito Hospital?
Santo Spirito Hospital is located in a historic area of Rome known for its stunning cathedral and notable monuments. If you're looking for a convenient place to stay, check out the 2031 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Santo Spirito Hospital?
Adjacent to Santo Spirito Hospital, Villa Agrippina Gran Meliá - The Leading Hotels of the World is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good options close by include Hotel Dei Mellini and Grand Hotel Olympic.
How many hotels will I be able to find close to Santo Spirito Hospital?
Expedia has 2031 hotels and other accommodations within a mile from Santo Spirito Hospital.
If I need to cancel the hotel reservation for my stay near Santo Spirito Hospital, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to get top deals close to Santo Spirito Hospital.
Where can I learn more about changing or cancelling my trip in the area near Santo Spirito Hospital?
For more information about changing or cancelling your stay near Santo Spirito Hospital, head over to our customer service page.
What can I see and do near Santo Spirito Hospital?
You might want to spend some time browsing the exhibits at Vatican Museums, Castel Sant'Angelo, or Cloister of Bramante. Piazza Navona, Pantheon, and Trevi Fountain are well-known local landmarks worth a visit. You can check out the local talent at Auditorium Conciliazione, Paul VI Audience Hall, and Sistina Theater.
How can I get to Santo Spirito Hospital?
With so many choices for transportation, seeing all of the area near Santo Spirito Hospital is simple. You can access metro transit at Venezia Tram Stop, Arenula-Cairoli Tram Station, and Barberini Station. If you'd like to explore more of the area, hop aboard a train from Rome Piazzale Flaminio Station, Rome Termini Station, or Rome (XRJ-Termini Rail Station).

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