Photo by Cindy Keese
Find all hotels by Best Western in Seneca, SC from AED 372
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Compare rooms and suites by Best Western in Seneca with rates, reviews, and availability. Most hotels are fully refundable.

Best Western Seneca-Clemson
Best Western Seneca-Clemson
8.4 out of 10, Very Good, (602)
The price is AED 372
AED 409 total
includes taxes & fees
2 Sep - 3 Sep
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Seneca Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Seneca Hotels by Brand
Hotels in Seneca Neighborhoods
More Hotel Options in Seneca
- Adventure Hotels in Seneca
- Beach Hotels in Seneca
- Business Hotels in Seneca
- Cheap Hotels in Seneca
- Family Hotels in Seneca
- Golf Hotels in Seneca
- Historic Hotels in Seneca
- Hotel Wedding Venues in Seneca
- Hotels with Bars in Seneca
- Hotels with Free Parking in Seneca
- Hotels with Hot Tubs in Seneca
- Hotels with WiFi in Seneca
- Hotels with a Pool in Seneca
- Hotels with smoking rooms in Seneca
- Luxury Hotels in Seneca
- Pet-friendly Hotels in Seneca
- Resorts & Hotels with Spas in Seneca
- Romantic Hotels in Seneca
- Shopping Hotels in Seneca
- Ski Hotels in Seneca
More Accommodation Types in Seneca
Explore more hotels
- Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
- 4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
- Fall fun at the cabin! Convenient to Lake Keowee and Clemson
- Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock
- 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
- Incredible 10 BR home with pool
- Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell
- Best Western Plus Clemson Hotel & Conference Center
- Days Inn by Wyndham Anderson
- Comfort Inn & Suites Clemson - University Area
- Inn @ Clemson
- Wooded Cottage - 3 Mi to Clemson University
- The Shepherd Hotel Downtown Clemson
- Horizon Inn & Suites
- Holiday Inn Express & Suites Clemson by IHG
- Baymont by Wyndham Easley/Greenville
- Clemson University's James F. Martin Inn
- The Inn at Patrick Square
- Hampton Inn Clemson-University Area
- Woodspring Suites Anderson North I-85