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Find Resorts & Hotels with Spas in Seneca, SC

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Check availability on Seneca Resorts & Hotels with Spas

Tonight
25 Oct - 26 Oct
Tomorrow
26 Oct - 27 Oct
Next weekend
31 Oct - 2 Nov
In two weeks
7 Nov - 9 Nov

Top Seneca Resorts & Hotels with Spas

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Recommended hotels in Seneca

Aerial view
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 star property
9.0 out of 10, Wonderful, (1002)
"Very beautiful place to stay"
United States
Steven
The price is AED 400
AED 497 total
includes taxes & fees
27 Oct - 28 Oct
Lakeside Lodge Clemson
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123
2.5 star property
8.0 out of 10, Very Good, (651)
"Friendly check in, clean room."
United States
connie
The price is AED 311
AED 365 total
includes taxes & fees
2 Nov - 3 Nov
Quality Inn Seneca Clemson Area US-123
Lobby
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 star property
8.4 out of 10, Very Good, (623)
"Convenient for Clemson visits."
United States
Kathleen
The price is AED 359
AED 395 total
includes taxes & fees
2 Nov - 3 Nov
Best Western Seneca-Clemson
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
9.4 out of 10, Exceptional, (199)
"Nice hotel by the lake"
United States
Mike
The price is AED 441
AED 485 total
includes taxes & fees
23 Nov - 24 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
9.8 out of 10, Exceptional, (43)
"The place was absolutely magnificent."
United States
David
The price is AED 474
AED 683 total
includes taxes & fees
27 Oct - 28 Oct
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lobby
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 star property
9.2 out of 10, Wonderful, (777)
"Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!"
United States
Gretchen
The price is AED 389
AED 427 total
includes taxes & fees
2 Nov - 3 Nov
Tru by Hilton Seneca Clemson
Exterior
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
9.4 out of 10, Exceptional, (648)
"Great place to stay"
United States
Jose
The price is AED 508
AED 558 total
includes taxes & fees
24 Nov - 25 Nov
Hampton Inn & Suites Seneca-Clemson Area
Property grounds
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
10.0 out of 10, Exceptional, (8)
"The location was perfect for what we needed last minute. Our hosts and hosts family were so friendly and welcoming. We absolutely adored the homestead and market that was set up and our son loved having all the animals around. Waking up to the chickens and the sunrise was the perfect start to each day!"
United States
Emily E.
The price is AED 422
AED 764 total
includes taxes & fees
4 Nov - 5 Nov
Charming 1-bedroom farmhouse in marvelous Seneca with WiFi, AC
Room, 1 King Bed, Non Smoking | Desk, free cribs/infant beds, rollaway beds, free WiFi
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
6.8 out of 10, (708)
"The rooms have been renovated it was nice and clean especially for the price. "
United States
Sherri
The price is AED 265
AED 292 total
includes taxes & fees
28 Oct - 29 Oct
Days Inn by Wyndham Seneca / Clemson Area
1 bedroom, iron/ironing board, WiFi, bed sheets
Boutique hotel in historic downtown Seneca. Room #4, King bed.
Boutique hotel in historic downtown Seneca. Room #4, King bed.
9.4 out of 10, Exceptional, (13)
"Great location, updated, well decorated, and very comfy. Great communication with property manager. "
United States
Ali R.
The price is AED 477
AED 777 total
includes taxes & fees
25 Nov - 26 Nov
Boutique hotel in historic downtown Seneca. Room #4, King bed.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"All good. "
Sharon 2-night trip
Posted 12 days ago
Hampton Inn & Suites Seneca-Clemson Area

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Frequently asked questions

Looking for a spa hotel in Seneca?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Check out the lakeside setting in Seneca - worth a picture or two! Be sure to enjoy the coffeehouses during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Seneca?
Take in the sights and attractions that Seneca offers with a visit to Keowee Reservoir, Lake Keowee, and Keowee Key Golf Course. If you have extra time while you're in the area, you might want to see Lake Hartwell and Oconee County Library Seneca Branch.
What is a Seneca spa hotel?
Spa hotels in Seneca provide lodging and have an on-site spa offering services including couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.