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Compare rooms and suites by La Quinta Inn & Suites in Seneca with rates, reviews, and availability. Most hotels are fully refundable.

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Top Seneca Hotel Reviews

5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!

10/10 Excellent

"All good "

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

10/10 Excellent

"This house was the ideal spot for a group of friends reuniting for Clemson Homecoming! There was ample space for hang-outs (both inside and out), more than enough bedrooms, and a fabulous view of the lake. The house was the perfect distance from campus and had everything we needed for the weekend. Steve was very kind and super responsive when we had questions about a a later checkout. Thank you for a wonderful stay! Would stay again and recommend to any family member or friend. "