Find Resorts & Hotels with Spas in Sikeston, MO

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Check availability on Sikeston Resorts & Hotels with Spas

Tonight
1 Feb - 2 Feb
Tomorrow
2 Feb - 3 Feb
Next weekend
6 Feb - 8 Feb
In two weeks
13 Feb - 15 Feb

Our top choices for Sikeston hotels with a spa

Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is AED 349
AED 394 total
includes taxes & fees
8 Feb - 9 Feb
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"This place feels like customer service from 1950. The service was outstanding "
Michael 4-night trip
Posted 9 days ago
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent
"Clean room with friendly staff."
Vicki 1-night trip
Posted 10 days ago
Drury Inn & Suites Jackson MO

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Frequently asked questions

Looking for a spa hotel in Sikeston?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers like the gourmet restaurants and popular shops in Sikeston. Enjoy the museums and riverfront during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Sikeston?
Experience Sikeston and visit Sikeston Depot Museum, Central Park, and Front Street Studio & Art Gallery. If you have a little extra time during your trip, you might want to make a stop at Stoddard County Civil War Memorial Cemetery and Hunter-Dawson State Historic Site.
What is a Sikeston spa hotel?
Spa hotels in Sikeston provide lodging and have an on-site spa offering services including therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.