A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Find Resorts & Hotels with Spas in Southwest Florida, FL

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November 2026

December 2026

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Our top choices for Southwest Florida hotels with a spa

A reception area with a large sign reading "MARGARIATVILL BEACH RESORT".

1. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Indulge in rejuvenating massage treatments at this oceanfront sanctuary with a full-service spa, outdoor pool, and white sand beach.

AED 918 total

includes taxes & fees

29 Nov - 30 Nov

2. The Westin Cape Coral Resort At Marina Village

Pelican

Refresh at a bayfront sanctuary with 5 treatment rooms, waterfront gardens, and rooftop relaxation spaces perfect for wellness seekers.

AED 763 total

includes taxes & fees

29 Nov - 30 Nov

A spa room with a large bathtub, a small table with towels and toiletries, and a bench.

3. Marriott Sanibel Harbour Resort & Spa

Punta Rassa

Luxuriate in a waterfront resort with 24 treatment rooms offering massages, aromatherapy, and reflexology in a full-service spa retreat.

AED 1,043 total

includes taxes & fees

29 Nov - 30 Nov

A hotel lobby with a large Buddha statue, a wall with the hotel's name and establishment year, and a modern interior design.

4. Shangri-La Springs

Bonita Springs

Indulge in tranquil luxury at this serene spa retreat with six treatment rooms, private patios, and lush gardens for a rejuvenating escape.

AED 586 total

includes taxes & fees

12 Nov - 13 Nov

A resort pool with a waterfall feature surrounded by palm trees and lounge chairs.

5. Naples Bay Resort & Marina

Oyster Bay

Soak in Florida luxury at this bayside spa retreat with hot stone massages and steam rooms for relaxation.

AED 1,125 total

includes taxes & fees

30 Nov - 1 Dec

A compact living space with a sofa, two armchairs, a dining table, and a kitchenette.

6. Lehigh Resort Club

Joel

AED 477 total

includes taxes & fees

15 Nov - 16 Nov

A spacious lobby with a modern design, featuring a wooden floor, comfortable seating areas, and large windows providing natural light.

7. Palmetto Marriott Resort & Spa

Palmetto

Immerse in total wellness at this Florida hotel with 7 treatment rooms, outdoor spa areas, and three pools for a restorative retreat.

AED 714 total

includes taxes & fees

22 Nov - 23 Nov

A reception area with a receptionist, a stone wall, and seating with round ottomans.

8. Hyatt Regency Coconut Point Resort & Spa

Bonita Springs

Retreat to this luxury bayside resort with 18 treatment rooms, four outdoor pools, and deep-tissue massages for a rejuvenating spa escape.

AED 1,749 total

includes taxes & fees

9 Dec - 10 Dec

A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

9. Pink Shell Beach Resort and Marina

Fort Myers Beach

AED 1,123 total

includes taxes & fees

15 Nov - 16 Nov

A modern lobby with a curved sofa, a flat-screen TV, and a reception desk.

10. Sunsuites Villas At Sunseeker Resort, Curio By Hilton

Charlotte Harbor

AED 1,194 total

includes taxes & fees

17 Nov - 18 Nov

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Choose what matters most at spa hotels in Southwest Florida

Pool

Breakfast included

Top Southwest Florida Hotel Reviews

A luxurious hallway with marble flooring, elegant furniture, and decorative lighting fixtures.

The St. Regis Longboat Key Resort

Longboat Key

10/10 Excellent

Jacob

A restaurant with wooden ceiling and walls, hanging pendant lights, and a long wooden bar.

Hollander Boutique Hotel

Downtown St. Petersburg

10/10 Excellent

Paul

A reception area with a wooden desk, a laptop, and a sign indicating a new offering.

Crystal Bay Historic Hotel

La Vista

10/10 Excellent

This hotel definately exceeded our expectations. Even though it is an old building (built in the early 1900s), the staff is very proud of its heritage and previous famous guests. They have done an outstanding job renovating and upkeeping this place. The hotel areas and rooms were impecably clean and the ambiance was from an old high vintage high class hotel. But the most noteworthy thing was their outstanding customer service. They treated us like family from the moment we checked in up to a...

Luis

Shangri-La Springs

Bonita Springs

10/10 Excellent

We had a very nice stay overnight at the charming Shangri La. We arrived late afternoon and checked out the next morning. The bed was comfortable and shower was great. Towels were good, just wish there was a place to hang them and clothing near the shower stall door while showering. The patio was a nice surprise and coming from a colder climate it was nice to sit there in January. The only real downside was that we heard lots of noise any time other guests rolled their bags down the sidewalk...

Kim

Pink Shell Beach Resort and Marina

Fort Myers Beach

10/10 Excellent

This is a wonderful place, the adult pool was priceless because of so many children. Food was exceptional for a resort, the only real gripe is the drink prices. 9 bucks for a draft Modelo in a plastic cup. I had two mixed drinks and the wife two Mocktails and it was $60 dollars. I get it, its a resort but they are making a killing off the booze, I noticed many folks just brought their own because of this. Lower the price and you will sell more.

TIMOTHY KEVIN

Sunsuites Villas At Sunseeker Resort, Curio By Hilton

Charlotte Harbor

10/10 Excellent

donaldo

A well-lit, spacious room with a central island, potted plants, and shelves stocked with products.

Olde Naples Hotel

Old Naples

10/10 Excellent

Mike

Palmetto Marriott Resort & Spa

Palmetto

10/10 Excellent

PAUL

A boutique hotel interior with a view of the beach, a mannequin, and various items on display.

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

Punta Gorda

10/10 Excellent

Kathleen

A modern cafe interior with a central island, shelves stocked with food items, and a counter with a menu.

The Ritz-Carlton Naples, Tiburón

Naples

10/10 Excellent

Casul Times

A luxurious indoor pool area with a sun lounger, a small table with a flower, and a large potted plant.

The Ritz-Carlton, Naples

Pelican Bay

10/10 Excellent

impecable!!!

Margaritaville Beach Resort Fort Myers

Fort Myers Beach

10/10 Excellent

Angela

The Westin Cape Coral Resort At Marina Village

Pelican

10/10 Excellent

danica

Find out more about Southwest Florida

Top Southwest Florida attractions for a relaxing vacation

Travelers seeking spa hotels in Southwest Florida will find a paradise of rejuvenating experiences. Begin your journey in Naples, where pristine beaches meet luxurious resorts, offering indulgent spa treatments featuring local ingredients like coconut and citrus. Explore the stunning Naples Botanical Garden, a perfect spot for a serene stroll amid vibrant floral displays, followed by a blissful massage at one of the nearby wellness retreats. In Fort Myers, the Calusa Nature Center and Planetarium invites you to unwind in nature, with tranquil trails perfect for reflection before returning to your hotel for a soothing evening soak. For those venturing to Sanibel Island, the shell-strewn beaches provide a backdrop for relaxation, while local spas offer unique treatments that incorporate the island’s natural beauty. The area around Estero Bay is another gem, where eco-tours can be paired with spa days, allowing for a perfect blend of adventure and pampering. With a plethora of upscale hotels featuring world-class spas, Southwest Florida ensures that your stay is not just about relaxation but an immersive experience in a region that celebrates both nature and luxury.

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Find Resorts & Hotels with Spas in Southwest Florida, FL

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southwest Florida hotels with a spa

1. Margaritaville Beach Resort Fort Myers

2. The Westin Cape Coral Resort At Marina Village

3. Marriott Sanibel Harbour Resort & Spa

4. Shangri-La Springs

5. Naples Bay Resort & Marina

6. Lehigh Resort Club

7. Palmetto Marriott Resort & Spa

8. Hyatt Regency Coconut Point Resort & Spa

9. Pink Shell Beach Resort and Marina

10. Sunsuites Villas At Sunseeker Resort, Curio By Hilton

Choose what matters most at spa hotels in Southwest Florida

Top Southwest Florida Hotel Reviews

The St. Regis Longboat Key Resort

10/10 Excellent

Find out more about Southwest Florida

Top Southwest Florida attractions for a relaxing vacation

Explore a world of travel with Expedia