St. Charles Vacations

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Find the Best St. Charles Vacation Packages

St. Charles Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
AED 548
AED 702 total
12 Oct - 13 Oct
includes taxes & fees
Ameristar Casino Resort and Spa
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO
Fully refundableReserve now, pay when you stay
AED 436
AED 501 total
4 Oct - 5 Oct
includes taxes & fees
8.2/10 Very Good! (1,004 reviews)
"Friendly and helpful staff. Very good breakfast and coffee. Clean rooms."

Reviewed on 26 September 2026

Hampton Inn St. Charles St. Peters
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO
Fully refundable
AED 537
AED 618 total
28 Sep - 29 Sep
includes taxes & fees
9.4/10 Exceptional! (1,097 reviews)
"Staff was welcoming and very helpful with a situation that occurred with our booking!"

Reviewed on 25 September 2026

Country Inn & Suites by Radisson, St. Charles Historic District
See all 2,470 properties in St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular St. Charles attractions

A brick-paved street lined with historic buildings and a yellow fire hydrant.

Historic Main Street

9.4/10 (538 reviews)
Missouri's first state capital (1821-1826) features over 100 specialty shops along brick-paved streets. Explore historic buildings with elegant restaurants and boutiques while immersing yourself in 19th-century charm.
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An indoor ice skating rink with a high ceiling and flags.

Family Arena

8.2/10 (179 reviews)
The Family Arena hosts everything from rock concerts to rodeos in its spacious 10,000-seat venue. Arrive early to explore the concessions and merchandise areas before settling in for the main event.
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A classic car with a shiny chrome grille and a golden eagle emblem.

Fast Lane Classic Cars

8.4/10 (62 reviews)
Explore showrooms of meticulously maintained classic cars and hot rods at Fast Lane Classic Cars. Knowledgeable staff share fascinating stories behind each vintage vehicle, delighting car enthusiasts.
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A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)
The Katy Trail spans 240 miles across Missouri on a historic railroad corridor, offering river views and charming towns. Cyclists and hikers can explore America's longest rail-trail while sampling local wineries.
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Ameristar Casino St. Charles

8.4/10 (763 reviews)
This expansive casino resort offers vibrant gaming, luxurious accommodations, and diverse dining. Enjoy sophisticated spa services or experience the lively atmosphere at RYSE Nightclub after trying your luck at the tables.
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St Charles Convention Center

8.4/10 (223 reviews)
This premier St. Louis area venue offers versatile spaces for conventions and social gatherings. Its direct connection to Embassy Suites hotel provides exceptional convenience for multi-day event attendees.
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Lindenwood University

8.6/10 (183 reviews)
Founded in 1832, Lindenwood University is the second-oldest higher-education institution west of the Mississippi. Explore its picturesque campus or catch a performance at the J. Scheidegger Center for the Arts.
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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)
Step back in time at this museum showcasing full-sized replicas of Lewis and Clark's expedition boats. Explore interactive exhibits and the state's largest indoor mural depicting the historic Missouri River journey.
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Frequently asked questions

How much does a St. Charles vacation package cost?
You can snap up a vacation package to this top destination on Expedia. But how much your vacation to St. Charles costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to St. Charles?
If you'd like to book a cheap St. Charles vacation package, consider planning a trip in December, January and February. You'll generally find better rates on flights and accommodations during these quieter months — perfect for a budget-friendly getaway.
How to find the best St. Charles package deals?
Start your search for a St. Charles package deal by entering your destination and preferred travel dates under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the ideal St. Charles package deal right away, simply switch up your dates and search again. Remember that deals are only available for a limited time, so book early and get your St. Charles getaway off to a flying start.
Is it cheaper to book a St. Charles vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll typically land a better deal than booking each component separately. And you'll still enjoy the flexibility to create a personalized St. Charles vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to St. Charles?
If you're considering a spontaneous St. Charles getaway, check out our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can land sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to St. Charles?
  1. Choose when to go: Check your diary and get your bags packed. Your favorite season and the activities on offer will also help you decide when to visit St. Charles.
  2. Set a budget: Consider expenses such as flights, food and transportation when working out how much to set aside for your trip to St. Charles. Then, choose a hotel that fits your budget, whether that's an affordable stay or a swankier retreat.
  3. Determine how many days away: Start by listing all the activities and sights you'd like to get to in St. Charles. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your bookings: With your travel dates in place, you can combine your flights, car rental, hotels and more into a customized St. Charles vacation package.

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