The Best 4 Star Hotels in St. Charles, MO from AED 280

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Our top choices for St. Charles 4-star hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

1. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

Tracy

AED 487 total

includes taxes & fees

27 Nov - 28 Nov

A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

2. 21C Museum Hotel St Louis

Downtown West

A.R.

AED 633 total

includes taxes & fees

15 Nov - 16 Nov

A buffet with fruits, pastries, and beverages.

3. Renaissance St. Louis Airport Hotel

Berkeley

Joy

AED 478 total

includes taxes & fees

20 Nov - 21 Nov

A rooftop restaurant with round tables, chairs, and a view of the city.

4. Moonrise Hotel

Delmar Loop

Rebecca

AED 650 total

includes taxes & fees

18 Nov - 19 Nov

The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

5. Live by Loews - St.Louis

Downtown St. Louis

brandon

AED 607 total

includes taxes & fees

15 Nov - 16 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

St. Charles

Carter

AED 744 total

includes taxes & fees

22 Nov - 23 Nov

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

7. The Royal Sonesta Chase Park Plaza St. Louis

Central West End

Sara

AED 754 total

includes taxes & fees

22 Nov - 23 Nov

A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

8. Le Méridien St. Louis Clayton

Clayton

Marsha

AED 658 total

includes taxes & fees

21 Nov - 22 Nov

A modern bathroom with a glass-enclosed shower, a large mirror, and wooden cabinets.

9. The Westin St. Louis

Downtown St. Louis

Stacy

AED 525 total

includes taxes & fees

15 Nov - 16 Nov

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

10. Marriott St. Louis Airport

Edmundson

Ravyn

AED 582 total

includes taxes & fees

20 Nov - 21 Nov

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

11. River City Casino & Hotel

St. Louis

jodi

AED 383 total

includes taxes & fees

8 Dec - 9 Dec

A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

12. Marriott St. Louis Grand

Downtown St. Louis

Laura

AED 553 total

includes taxes & fees

22 Nov - 23 Nov

A bar area with a central bar, multiple stools, and a chandelier.

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Downtown St. Louis

Anastasia

AED 415 total

includes taxes & fees

23 Nov - 24 Nov

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

14. Drury Plaza Hotel St. Louis Brentwood

Brentwood

Stacey Rochelle

AED 558 total

includes taxes & fees

22 Nov - 23 Nov

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

15. The Cheshire

Richmond Heights

Matthew

AED 650 total

includes taxes & fees

29 Nov - 30 Nov

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis

Megan

AED 479 total

includes taxes & fees

8 Dec - 9 Dec

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

Stephanie

AED 448 total

includes taxes & fees

22 Nov - 23 Nov

A modern lounge area with a central fire feature, seating, and large windows offering a city view.

18. Hilton St. Louis at the Ballpark

Downtown St. Louis

Kella

AED 605 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West

William

AED 677 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.

20. Hilton Pennywell St. Louis at the Arch

Downtown St. Louis

Jacqueline

AED 471 total

includes taxes & fees

15 Nov - 16 Nov

Top St. Charles Hotel Reviews

Ameristar Casino Resort and Spa

St. Charles

10/10 Excellent

Quintina

Drury Plaza Hotel St. Louis Brentwood

Brentwood

10/10 Excellent

Lisa

A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.

DoubleTree by Hilton Hotel St. Louis - Chesterfield

Chesterfield

10/10 Excellent

I had a pleasant stay. I was there for two nights and a day. I enjoyed the indoor pool and fitness center. Both areas were well kept, in working conditions and stocked with plenty of towels and wipes at the gym. The staff were friendly and helpful. The breakfast buffet was okay, good selection but food quality could have been better. The room was clean and in working order. I would recommend to others and stay again!

Deshawn

An indoor swimming pool with blue tiles, surrounded by lounge chairs and potted plants.

DoubleTree by Hilton St. Louis - Westport

Westport

10/10 Excellent

Anonymous traveler

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

AC Hotel St. Louis Central West End

Central West End

10/10 Excellent

Joanne

Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis

10/10 Excellent

Journey

Marriott St. Louis Airport

Edmundson

10/10 Excellent

Elbert

Live by Loews - St.Louis

Downtown St. Louis

10/10 Excellent

Jennifer

21C Museum Hotel St Louis

Downtown West

10/10 Excellent

Julian

River City Casino & Hotel

St. Louis

10/10 Excellent

David

Hyatt Regency St. Louis at The Arch

Downtown St. Louis

10/10 Excellent

Tracy

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

DoubleTree by Hilton St. Louis Airport

Woodson Terrace

10/10 Excellent

Tionna

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

10/10 Excellent

I'll be honest, when I first pulled up I got American Horror Story: Hotel vibes. It's definitely an odd hotel but my overall experience there was good. The staff was friendly and the rooms were clean (and was all one color). The rooftop lounge was a great place to take in the skyline and have a drink. I don't know if they had room service because I usually bring my own snacks and what not. The location was convenient, however; I wouldn't go strolling around at night or solo. It's literally on...

Tim

Hilton Pennywell St. Louis at the Arch

Downtown St. Louis

10/10 Excellent

Jacqueline

Frequently Asked Questions

What are the best 4-star hotels in St. Charles?

If you're seeking high-quality comfort and lots of amenities during your St. Charles retreat, check in to Ameristar Casino Resort and Spa. This sought-after 4-star hotel comes with premium bedding and concierge services. DoubleTree by Hilton St. Louis - Westport also gets stellar reviews from Expedia guests. Concierge services and a swimming pool are among its conveniences.

How much does it cost to stay in a 4-star hotel in St. Charles?

To find a 4-star hotel in St. Charles that fits your budget, use Expedia's sort and search filters. Check out the availability during your vacation dates and use our pricing filter to set your maximum rate. You can also list your results by the most wallet-friendly option first.

Search for the lowest price from AED 280

What's the difference between 5-star and 4-star hotels in St. Charles?

Treat yourself to luxury during your St. Charles getaway by choosing a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and special one. Round-the-clock concierge assistance, elegant furnishings and gourmet dining are just the start of the first-rate services and conveniences you'll likely have access to.

Does St. Charles have any 4-star all-inclusive resorts?

Search for a 4-star all-inclusive hotel in St. Charles by using Expedia's handy filters. If nothing is available, we do have a number of other choices in this city that make the perfect base for your escape. DoubleTree by Hilton St. Louis - Westport and Ameristar Casino Resort and Spa are both rated 4 stars and offer a fantastic balance between amenities, comfort and affordability.

What are the top 4-star hotels in downtown St. Charles?

Enjoy the city sights with ease when you stay at Ameristar Casino Resort and Spa. About 5 kilometers southeast from central St. Charles, this 4-star hotel offers the perfect location to access the best of this bustling city with the added convenience of a spa and premium bedding.

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Find 4 Star Hotels in St. Charles, MO from AED 280

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for St. Charles 4-star hotels

1. Hyatt Regency St. Louis at The Arch

2. 21C Museum Hotel St Louis

3. Renaissance St. Louis Airport Hotel

4. Moonrise Hotel

5. Live by Loews - St.Louis

6. Ameristar Casino Resort and Spa

7. The Royal Sonesta Chase Park Plaza St. Louis

8. Le Méridien St. Louis Clayton

9. The Westin St. Louis

10. Marriott St. Louis Airport

11. River City Casino & Hotel

12. Marriott St. Louis Grand

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

14. Drury Plaza Hotel St. Louis Brentwood

15. The Cheshire

16. Embassy Suites by Hilton St. Louis Downtown

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

18. Hilton St. Louis at the Ballpark

19. St. Louis Union Station Hotel, Curio Collection by Hilton

20. Hilton Pennywell St. Louis at the Arch

Top St. Charles Hotel Reviews

Ameristar Casino Resort and Spa

10/10 Excellent

Frequently Asked Questions

What are the best 4-star hotels in St. Charles?

How much does it cost to stay in a 4-star hotel in St. Charles?

What's the difference between 5-star and 4-star hotels in St. Charles?

Does St. Charles have any 4-star all-inclusive resorts?

What are the top 4-star hotels in downtown St. Charles?

Explore a world of travel with Expedia