The Best Business Hotels in St. Louis, MO from AED 301 in 2026

A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Our top choices for St. Louis business-friendly hotels

An indoor pool area with a hot tub, seating, and a stone wall.

1. Drury Plaza Hotel St. Louis Union Station

Downtown West

Andrea

AED 494 total

includes taxes & fees

15 Nov - 16 Nov

A rooftop terrace with rows of metal chairs and a view of city buildings.

2. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Theresa

AED 618 total

includes taxes & fees

9 Nov - 10 Nov

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

3. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

Tracy

AED 542 total

includes taxes & fees

25 Nov - 26 Nov

4. Pear Tree Inn St. Louis Near Union Station

Downtown West

Larry

AED 447 total

includes taxes & fees

15 Nov - 16 Nov

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

5. Live by Loews - St.Louis

Downtown St. Louis

brandon

AED 607 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

6. Wingate by Wyndham St. Louis Airport

St. Ann

Cindy

AED 391 total

includes taxes & fees

4 Nov - 5 Nov

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

7. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis

Megan

AED 590 total

includes taxes & fees

27 Nov - 28 Nov

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

8. La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis

Edward

AED 421 total

includes taxes & fees

29 Oct - 30 Oct

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Top St. Louis Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Great value. Breakfast and dinner free each night along with 3 drinks. Walk to Arch and across from the historic courthouse. Staff was helpful and very friendly."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"This is my 2nd stay at Pear Tree and everything about this hotel is EXCELLENT which is why I had a return visit. I attended another concert in STL (my home away from home) and Pear Tree's location is always a definite POSITIVE, we were mins away from Enterprise Center which makes everything so convenient. The staff always SUPER HELPFUL IN ALL ASPECTS! SPECIAL SHOUT OUT TO MS DORIS (Black lady with salt & pepper hair) YOU ARE THE BEST, THANKS AGAIN FOR EVERYTHING 💪❤️!! See yall soon 😉"

Ameristar Casino Resort and Spa

10/10 Excellent

"I was kind of worried staying here, especially with the deal that was going on but truly no regrets. Upon check in, they had multiple staff members available which is uncommon these days and they were nice. We booked a regular king suite and it was huge and spotless! They have an indoor/outdoor pool and jacuzzi available, they were huge. We did stay during the week so the restaurants were not operating at they do on the weekends but they still have a little “deli” available all night with some quick decent options or you can always doordash. They serve coffee/breakfast as well. I did not know until we went to the casino that people could smoke. The upper level of the casino is non smoking but there was no bar up there, not really any people either so we decided to just be mindful of where we sat down stairs. Bar is reasonably priced as well. The only thing that I found annoying was that the machines would be dirty as in cigarette ashes and ashtrays so I would have to move along to find something clean. They have vending available by the check in desk and in the same hallway as the casino. Definitely would return."

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Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis Union Station