Find Business Hotels in St. Louis, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on St. Louis Business Hotels
Our top choices for St. Louis business-friendly hotels
8.4 out of 10, Very Good, (1,034 reviews)
"Very clean and comfortable. Very kind and helpful staff. Would stay again!"
Lindsey
The price is AED 262
AED 301 total
includes taxes & fees
19 Jul - 20 Jul
9.2 out of 10, Wonderful, (3,095 reviews)
"It was a great place to stay. We stay 1 night and everything was great."
rueben
The price is AED 331
AED 389 total
includes taxes & fees
26 Jul - 27 Jul
8.6 out of 10, Excellent, (4,220 reviews)
"I enjoyed the breakfast and the people that were there were very friendly."
Luella
The price is AED 512
AED 604 total
includes taxes & fees
17 Jul - 18 Jul
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,049 reviews)
"very nice and clean room, breakfast selection was very nice, the staff was very courteous and professional. We will stay there again. "
Helmuth
The price is AED 308
AED 363 total
includes taxes & fees
19 Jul - 20 Jul
9.2 out of 10, Wonderful, (377 reviews)
"Was a good place to stay"
Blake
The price is AED 350
AED 404 total
includes taxes & fees
19 Jul - 20 Jul
9.2 out of 10, Wonderful, (1,661 reviews)
"Friendly staff and clean room, great value"
Christian
The price is AED 349
AED 460 total
includes taxes & fees
3 Aug - 4 Aug
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
7.8 out of 10, Good, (1,431 reviews)
"Room was very nice with very comfortable beds and pillows."
rodney
The price is AED 347
AED 400 total
includes taxes & fees
13 Jul - 14 Jul
9.2 out of 10, Wonderful, (1,674 reviews)
"Very nice hotel for the price! Would definitely stay there again in the future!"
Lori
The price is AED 357
AED 416 total
includes taxes & fees
28 Jul - 29 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top St. Louis Hotel Reviews
Clayton Plaza Hotel & Extended Stay
8/10 Good
Explore a world of travel with Expedia
Top neighborhoods for Business Hotels
Find More Hotels near St. Louis
More Hotel Options in St. Louis
- Adults Only Resorts & Hotels in St. Louis
- Adventure Hotels in St. Louis
- Beach Hotels in St. Louis
- Boutique Hotels in St. Louis
- Casinos in St. Louis
- Cheap Hotels in St. Louis
- Family Hotels in St. Louis
- Golf Hotels in St. Louis
- Historic Hotels in St. Louis
- Hotel Wedding Venues in St. Louis
- Hotel with a Concierge in St. Louis
- Hotels with Bars in St. Louis
- Hotels with Early Check-in in St. Louis
- Hotels with Free Parking in St. Louis
- Hotels with Hot Tubs in St. Louis
- Hotels with Waterslides in St. Louis
- Hotels with WiFi in St. Louis
- Hotels with a Pool in St. Louis
- Hotels with an Indoor Pool in St. Louis
- Hotels with smoking rooms in St. Louis
- Luxury Hotels in St. Louis
- Pet-friendly Hotels in St. Louis
- Resorts & Hotels with Spas in St. Louis
- Romantic Hotels in St. Louis
- Shopping Hotels in St. Louis
- Ski Hotels in St. Louis
- Waterpark Hotels in St. Louis
- Winery Hotels in St. Louis
More Accommodation Types in St. Louis
- Vacation Homes in Missouri
- Condo Rentals in Missouri
- Apartments in Missouri
- Cabin Rentals in Missouri
- Cottages in Missouri
- Motels in Missouri
- Lodges in Missouri
- Resorts in Missouri
- Chalets in Missouri
- Villas in Missouri
- B&B in Missouri
- Farmstay in Missouri
- RV Parks in Missouri
- Aparthotels in Missouri
- Guest Houses in Missouri
- Inns in Missouri
- Hostels in Missouri
- Houseboats in Missouri
Hotels near popular St. Louis Attractions
St. Louis Hotels by Star Rating
Explore more hotels
- Live by Loews - St.Louis
- River City Casino & Hotel
- Drury Plaza Hotel St. Louis Union Station
- Hilton St. Louis at the Ballpark
- Pear Tree Inn St. Louis Near Union Station
- The Westin St. Louis
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Home2 Suites by Hilton St. Louis Downtown
- 21C Museum Hotel St Louis
- Best Western St. Louis Inn
- Marriott St. Louis Grand
- Hilton St. Louis Frontenac
- Renaissance St. Louis Airport Hotel
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Courtyard by Marriott St. Louis Downtown/Convention Center
- Tru By Hilton St. Louis Downtown
- The Wildwood Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Casino Queen Hotel