A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Business Hotels in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Business Hotels

This weekend
Next weekend

Our top choices for St. Louis business-friendly hotels

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
St. Ann
9.2 out of 10, Wonderful, (3,055 reviews)
"Close to airport, good rate."
United States
Gary
The price is AED 331
AED 389 total
includes taxes & fees
14 Jul - 15 Jul
Pear Tree Inn St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
St. Ann
9.2 out of 10, Wonderful, (1,692 reviews)
"Excelent breakfast, clean room, friendly staff."
United States
Irmaris
The price is AED 421
AED 496 total
includes taxes & fees
12 Jul - 13 Jul
Wingate by Wyndham St. Louis Airport

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,172 reviews)
"This was one of the nicest hotels I have ever stayed at for a very affordable price. We would definitely stay here again."
United States
Elisha
The price is AED 515
AED 608 total
includes taxes & fees
17 Jul - 18 Jul
Hyatt Regency St. Louis at The Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.6 out of 10, Exceptional, (3,534 reviews)
"Wonderful place to stay in St Louis! Great location, great staff, wonderful breakfast buffet, and reasonably priced!"
United States
Christopher
The price is AED 562
AED 657 total
includes taxes & fees
17 Jul - 18 Jul
Drury Plaza Hotel St. Louis at the Arch

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
Edmundson
9.2 out of 10, Wonderful, (1,306 reviews)
"Great stay! Close to airport and shuttles were prompt & courteous!"
United States
Dana
The price is AED 470
AED 552 total
includes taxes & fees
20 Jul - 21 Jul
Drury Inn & Suites St. Louis Airport

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,203 reviews)
"Incredible stay!!"
United States
Jessica
The price is AED 499
AED 579 total
includes taxes & fees
22 Jul - 23 Jul
Drury Plaza Hotel St. Louis Chesterfield

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,008 reviews)
"Place was clean, staff was very friendly loved the hot tub!"
United States
Sophia
The price is AED 470
AED 550 total
includes taxes & fees
19 Jul - 20 Jul
Drury Inn & Suites Southwest St. Louis

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1,001 reviews)
"Great stay for night before flying out."
United States
Andrew
The price is AED 404
AED 497 total
includes taxes & fees
2 Aug - 3 Aug
Hyatt Select St. Louis Airport

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,400 reviews)
"Will definitely stay again!"
United States
Trevor
The price is AED 347
AED 400 total
includes taxes & fees
5 Jul - 6 Jul
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,038 reviews)
"We enjoyed our stay. The staff was very nice and the hotel was well kept and clean."
United States
Patrice
The price is AED 308
AED 363 total
includes taxes & fees
6 Jul - 7 Jul
Sleep Inn & Suites O'Fallon MO - Technology Drive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Louis Hotel Reviews

Explore a world of travel with Expedia