A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Business Hotels in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Business Hotels

Tonight
4 Oct - 5 Oct
Tomorrow
5 Oct - 6 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for St. Louis business-friendly hotels

A rooftop terrace with wicker furniture, offering a city view.
A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.
A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.
A lobby with seating areas, a chandelier, and a large pillar.

1. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
Downtown St. Louis
United States
Kevin Roy
AED 496
AED 580 total
includes taxes & fees
8 Oct - 9 Oct
Drury Plaza Hotel St. Louis at the Arch
A lobby with a sofa, two armchairs, a coffee table, and a staircase.
A park with a pathway, trees, and a modern sculpture.
A rooftop lounge with large windows, red seating, and a view of the cityscape.
A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.

2. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
United States
David
AED 526
AED 620 total
includes taxes & fees
30 Oct - 31 Oct
Hyatt Regency St. Louis at The Arch
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.
A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.
A pool area with two hot tubs, seating, and a view of the outdoors.
A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

3. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
Edmundson
United States
Lori
AED 422
AED 496 total
includes taxes & fees
11 Oct - 12 Oct
Drury Inn & Suites St. Louis Airport
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.
A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.
A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.
A hotel room with a bed, a desk, a television, and a lamp.

4. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
St. Ann
United States
Murphy
AED 331
AED 389 total
includes taxes & fees
11 Oct - 12 Oct
Pear Tree Inn St. Louis Airport
An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.
A hotel dining area with multiple tables and chairs, a central island, and pendant lighting.
A hotel with a prominent arch structure in the background, a sign for Hampton Inn, and a TGI Friday's restaurant.
A compact minibar with a refrigerator, coffee maker, and beverage dispensers.

5. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Downtown St. Louis
United States
Andy
AED 389
AED 454 total
includes taxes & fees
26 Oct - 27 Oct
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.
A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.
A multi-story hotel with a stone facade, a covered entrance, and a parking lot.
A modern lobby with blue seating, a reception desk, and large windows.

6. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
Woodson Terrace
United States
Will
AED 404
AED 497 total
includes taxes & fees
11 Oct - 12 Oct
Hyatt Select St. Louis Airport
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.
A hotel room with a desk, chair, TV, and a framed picture on the wall.
A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.
A hotel room with two beds, a desk, a chair, and a large window with curtains.

7. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
St. Ann
United States
Mary
AED 356
AED 419 total
includes taxes & fees
11 Oct - 12 Oct
Wingate by Wyndham St. Louis Airport
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A buffet area with various food items and a self-service station.
An indoor swimming pool area with lounge chairs, a small table, and potted plants.
A bar area with a long counter, multiple stools, and a television mounted on the wall.

8. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United States
Karen
AED 419
AED 498 total
includes taxes & fees
18 Oct - 19 Oct
Embassy Suites by Hilton St. Louis Downtown
A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.
A modern lounge area with a stone wall, a flat-screen TV, a fireplace, and comfortable seating.
An outdoor seating area with multiple tables and chairs, large umbrellas, and a built-in fire feature against a stone wall.
A modern living room with a fireplace, a large forest-themed painting, and a cozy seating area with a sofa and a coffee table.

9. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
Downtown West
United States
James
AED 426
AED 508 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott St. Louis Downtown
A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.
A modern hotel lobby with a checkered floor, a seating area with a sofa and armchairs, and a bar area with red chairs.
A modern hotel lobby with a large sofa, a television, and a bar area.
A lobby with a checkered floor, red and grey seating, and a staircase.

10. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
Downtown St. Louis
United States
Kristy
AED 356
AED 423 total
includes taxes & fees
31 Oct - 1 Nov
Courtyard by Marriott St. Louis Downtown/Convention Center
View all properties

Top St. Louis Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Nice place for me and my daughter to stay, felt safe and the pool was warm."
Tabetha 1-night trip
Posted 1 hour ago
Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"The staff was very helpful and friendly especially the breakfast staff, Lavern would greet each person with a smile. She is so sweet. It is a beautiful historic hotel."
Michelle 2-night trip
Posted 2 hours ago
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Nice hotel"
Shannon 1-night trip
Posted 4 hours ago
Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Great location Easy parking Wonderful staff Clean room"
Micah 1-night trip
Posted 11 hours ago
Drury Plaza Hotel St. Louis Union Station
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"I have no complaints about this hotel. The staff was pleasant and helpful. It was wonderfully clean throughout. The Renaissance Hotel has my highest recommendation as a wonderful place to stay."
Rosalind 2-night trip
Posted 13 hours ago
Renaissance St. Louis Airport Hotel
Forest Park Hotel by MDR

Forest Park Hotel by MDR

10/10 Excellent
"Employees were very helpful. Room was clean. Got new towels daily. Only issue was the elevator. It was very slow and there was low occupancy the time I was there."
charles 3-night trip
Posted 17 hours ago
Forest Park Hotel by MDR
The Cheshire

The Cheshire

8/10 Good
"There was different types of hair where the coffee items sit. Feel like that area should be spotless. Bed was very comfortable. A/C worked great!"
TAMMY R 1-night trip
Posted 1 day ago
The Cheshire
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Walking distance to Lambo"
Wendy 1-night trip
Posted 2 days ago
Hollywood Casino & Hotel St. Louis

Explore a world of travel with Expedia