A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Business Hotels in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Business Hotels

Tonight
23 Oct - 24 Oct
Tomorrow
24 Oct - 25 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for St. Louis business-friendly hotels

A rooftop terrace with rows of metal chairs and a view of city buildings.
A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.
A hotel room with a large window offering a view of the Gateway Arch and a modern building.
A lobby with seating areas, a chandelier, and a large pillar.

1. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
Downtown St. Louis
United States
Theresa
AED 496
AED 580 total
includes taxes & fees
27 Oct - 28 Oct
Drury Plaza Hotel St. Louis at the Arch
A lobby with a sofa, two armchairs, a coffee table, and a staircase.
A park with a pathway, trees, and a modern sculpture.
A rooftop lounge with large windows, red seating, and a view of the cityscape.
A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.

2. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
United States
Johnny
AED 493
AED 581 total
includes taxes & fees
30 Oct - 31 Oct
Hyatt Regency St. Louis at The Arch
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.
A hotel reception area with a counter, seating, and a staircase.
A pool area with two hot tubs, seating, and a view of the outdoors.
A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

3. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
Edmundson
United States
Ethan
AED 422
AED 500 total
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites St. Louis Airport
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.
A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.
A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.
A hotel room with a desk, chair, TV, and a framed picture on the wall.

4. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
St. Ann
United States
Cindy
AED 330
AED 391 total
includes taxes & fees
29 Oct - 30 Oct
Wingate by Wyndham St. Louis Airport
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A spacious lobby with striped chairs, a central coffee table, and large potted plants.
A bar area with a long counter, multiple stools, and a television mounted on the wall.
An indoor swimming pool area with lounge chairs, a small table, and potted plants.

5. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United Kingdom
Luke
AED 418
AED 498 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites by Hilton St. Louis Downtown
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.
A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.
A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.
A hotel room with a bed, a desk, a television, and a lamp.

6. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
St. Ann
United States
Curtiss
AED 331
AED 392 total
includes taxes & fees
27 Oct - 28 Oct
Pear Tree Inn St. Louis Airport
A modern kitchen with a bar area, wooden cabinets, and pendant lighting.
A modern hotel entrance with a glass canopy, large windows, and a brick facade.
A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.
A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

7. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
Chesterfield
United States
Debbie
AED 443
AED 514 total
includes taxes & fees
25 Oct - 26 Oct
Hyatt Place St. Louis/Chesterfield
A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.
A gym with treadmills, exercise bikes, and a mirror.
A snack display area with various packaged snacks and a refrigerated section.
Pool

8. Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
St. Louis
United States
Kevin
AED 403
AED 463 total
includes taxes & fees
30 Oct - 31 Oct
Hampton Inn & Suites St. Louis/South I-55
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.
A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.
A modern lobby with blue seating, a reception desk, and large windows.
A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

9. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
Woodson Terrace
United States
Daisy
AED 404
AED 501 total
includes taxes & fees
29 Oct - 30 Oct
Hyatt Select St. Louis Airport
A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.
A spacious lobby with a bar area, seating arrangements, and a fireplace.
A lobby with a clock, a sign for The Merchants' Laclede National Bank, and a security vault.
A hotel room with two beds, a TV, a desk, and a chair.

10. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
Downtown St. Louis
United States
Mary
AED 403
AED 471 total
includes taxes & fees
15 Nov - 16 Nov
Hilton Pennywell St. Louis at the Arch
View all properties

Top St. Louis Hotel Reviews

The Westin St. Louis

The Westin St. Louis

10/10 Excellent
"Great location! Clean room."
Liverio 2-night trip
Posted 4 hours ago
The Westin St. Louis
Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center

10/10 Excellent
"Clean room."
Deborah 1-night trip
Posted 6 hours ago
Courtyard by Marriott St. Louis Downtown/Convention Center
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"We enjoyed the fresh popcorn and it was within walking distance from the train station."
Tamela 1-night trip
Posted 7 hours ago
Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Great location, friendly staff. Well maintained and clean."
Matt 1-night trip
Posted 8 hours ago
Drury Plaza Hotel St. Louis Union Station

Explore a world of travel with Expedia