The Best Business Hotels in St. Louis, MO from AED 301 in 2026 | Expedia

A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Check availability on St. Louis Business Hotels

Tonight

12 Oct - 13 Oct

Tomorrow

13 Oct - 14 Oct

This weekend

16 Oct - 18 Oct

Next weekend

23 Oct - 25 Oct

Our top choices for St. Louis business-friendly hotels

A rooftop terrace with wicker furniture, offering a city view.

A hotel room with a large window offering a view of the Gateway Arch and a modern building.

A lobby with seating areas, a chandelier, and a large pillar.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

1. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

United States

Theresa

AED 496

AED 580 total

includes taxes & fees

18 Oct - 19 Oct

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

A rooftop lounge with large windows, red seating, and a view of the cityscape.

A park with a pathway, trees, and a modern sculpture.

A spacious lobby with a sectional sofa, a white armchair, and a glass coffee table. There is a dining area in the background with a chandelier.

2. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

United States

Johnny

AED 493

AED 581 total

includes taxes & fees

30 Oct - 31 Oct

An indoor pool area with a hot tub, seating, and a stone wall.

A hotel room with a large bed, two bedside lamps, a framed picture on the wall, and a blue armchair.

A gym with treadmills, elliptical machines, and a stationary bike.

An indoor pool area with a hot tub, lounge chairs, and a towel service station.

3. Drury Plaza Hotel St. Louis Union Station

Downtown West

United States

James A.

AED 415

AED 494 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

A hotel with a prominent arch structure in the background, a sign for Hampton Inn, and a TGI Friday's restaurant.

A compact minibar with a refrigerator, coffee maker, and beverage dispensers.

A hotel lobby with a bar area, seating, and a large window.

4. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis

United States

Andrew

AED 408

AED 477 total

includes taxes & fees

29 Oct - 30 Oct

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

A spacious lobby with striped chairs, a central coffee table, and large potted plants.

A bar area with a long counter, multiple stools, and a television mounted on the wall.

An indoor swimming pool area with lounge chairs, a small table, and potted plants.

5. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis

United Kingdom

Luke

AED 434

AED 516 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A hotel room with a bed, a desk, a television, and a lamp.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

6. Pear Tree Inn St. Louis Airport

St. Ann

United States

Murphy

AED 331

AED 392 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

7. Wingate by Wyndham St. Louis Airport

St. Ann

United States

Mary

AED 356

AED 422 total

includes taxes & fees

19 Oct - 20 Oct

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

8. Hyatt Place St. Louis/Chesterfield

Chesterfield

United States

Debbie

AED 443

AED 514 total

includes taxes & fees

18 Oct - 19 Oct

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Top St. Louis Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

8/10 Good

"The location is excellent! Walking distance to the aquarium and union station. There is garage parking. There is free breakfast and dinner. The only thing I would have liked a slightly bigger room. But the rooms were clean and quiet."

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center

10/10 Excellent

"The whole staff was amazing"

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"friendly staff, great for kids"

Moonrise Hotel

Moonrise Hotel

10/10 Excellent

"Such a cute place to stay, and convenient to a music venue and restaurants."

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good

"Wonderful stay for a small bachelorette party. Had a wonderful time!"

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