The Best Business Hotels in St. Louis, MO from AED 287 in 2026

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Our top choices for St. Louis business-friendly hotels

A rooftop terrace with wicker furniture, offering a city view.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.

A lobby with seating areas, a chandelier, and a large pillar.

1. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Theresa

AED 496

AED 580 total

includes taxes & fees

25 Oct - 26 Oct

An indoor pool area with a hot tub, seating, and a stone wall.

A reception desk with a marble top, wooden paneling, and a sign indicating it's the Drury Inn.

An indoor pool area with a hot tub, lounge chairs, and a towel service station.

2. Drury Plaza Hotel St. Louis Union Station

Downtown West

James A.

AED 415

AED 494 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

A park with a pathway, trees, and a modern sculpture.

A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.

A rooftop lounge with large windows, red seating, and a view of the cityscape.

3. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

Johnny

AED 493

AED 581 total

includes taxes & fees

30 Oct - 31 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

4. Wingate by Wyndham St. Louis Airport

St. Ann

Mary

AED 356

AED 422 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

5. Pear Tree Inn St. Louis Airport

St. Ann

Murphy

AED 331

AED 392 total

includes taxes & fees

22 Oct - 23 Oct

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

A modern dining area with multiple tables and chairs, large windows offering a view of the outdoors, and a mix of natural and artificial lighting.

A modern hotel lobby with a cityscape view, a reception desk, and ambient lighting.

A modern hotel lobby with a seating area, a desk, and large windows offering a view of the outside.

6. La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis

Edward

AED 368

AED 428 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

A hotel dining area with multiple tables and chairs, a central island, and pendant lighting.

A compact minibar with a refrigerator, coffee maker, and beverage dispensers.

A hotel lobby with a bar area, seating, and a large window.

7. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis

Andrew

AED 404

AED 472 total

includes taxes & fees

25 Oct - 26 Oct

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

A bar area with a long counter, multiple stools, and a television mounted on the wall.

A spacious lobby with striped chairs, a central coffee table, and large potted plants.

A buffet area with various food items and a self-service station.

8. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis

Luke

AED 434

AED 516 total

includes taxes & fees

26 Oct - 27 Oct

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Top St. Louis Hotel Reviews

Moonrise Hotel

10/10 Excellent

"Had the Vincent Price suite with a city view. Also loved the rooftop terrace."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"The gentleman at check in was very pleasant. The room was tidy and linens were clean. Air conditioning was cold, but ticked/was on the louder side. Kick-back hours was not the normal kick-back we are used to after staying at other Drury hotels; they only had chips and popcorn so we ended up going out. The pool is outside so it was already sealed for the colder weather. It was in a great location near the airport and offered shuttle service! Convenient for us overall."

Forest Park Hotel by MDR

10/10 Excellent

"Great, great, great property. well restored, you know, rung back. You tell us it’s buildings older. Amenities are great. Staff’s great, clean. go above and beyond to try to be helpful as much as they can. I felt safe. Yeah, all around good property"

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Check availability on St. Louis Business Hotels

Our top choices for St. Louis business-friendly hotels

1. Drury Plaza Hotel St. Louis at the Arch