The Best Hotels Closest to St. Louis Science Center in St. Louis for 2026

A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for St. Louis Science Center hotels

A lobby with a reception desk, seating area, and a bicycle in the background.

A spacious dining area with multiple tables and chairs, a kitchen area, and a flat-screen TV mounted on the wall.

A conference room with a long table, chairs, water bottles, and a projector screen.

1. Drury Inn & Suites St. Louis Forest Park

2 km from St. Louis Science Center

Robert

AED 496

AED 580 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A snack and treat display with various products, including chips and beverages, in a store setting.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

2. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 1 km from St. Louis Science Center

Jennifer

AED 509

AED 600 total

includes taxes & fees

7 Oct - 8 Oct

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

A grand lobby with a central seating area, a staircase, and a decorative ceiling.

An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.

A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

3. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 1.8 km from St. Louis Science Center

Tosha

AED 591

AED 806 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern hotel lobby with a marble reception desk, a bar area, and a seating space.

A hotel with a modern facade, large windows, and a sign reading "AC HOTEL CENTRAL WEST END".

A modern kitchen with a marble backsplash, built-in bar with stools, and shelves stocked with bottles.

4. AC Hotel St. Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Molly

AED 574

AED 677 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with seating, planters, and a grill.

A spacious lobby with a modern design, featuring a seating area with sofas and armchairs, a reception desk, and a large window providing a view of the interior.

A modern bar area with a long counter, bar stools, and a variety of bottles.

A building with a sign that reads "element by Westin" on a brick wall.

5. Element by Marriott St. Louis Midtown

Midtown, 2.7 km from St. Louis Science Center

Heather

AED 485

AED 567 total

includes taxes & fees

5 Oct - 6 Oct

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

A group of people sitting on a couch in a well-lit room with a large plant and a floor lamp.

A modern bar area with a long counter, bar stools, and a television mounted on the wall.

A modern cafe interior with a bar area, seating, and a menu board.

6. Hotel Indigo St Louis - Central West End by IHG

Central West End, 1.7 km from St. Louis Science Center

Lydia

AED 492

AED 621 total

includes taxes & fees

1 Nov - 2 Nov

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

A building with a brick facade, a covered entrance, and a tree adorned with string lights.

A spacious dining area with marble tables and chairs, a kitchen in the background, and a modern ceiling design.

A spacious lobby with grey sofas, wooden coffee tables, and potted plants.

7. The West End

Central West End, 2.3 km from St. Louis Science Center

Sergio

AED 305

AED 430 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

A modern bar area with seating, a bar counter, and a view of the cityscape.

A pool area with clear water, red lounge chairs, and a view of the outside through large windows.

A modern hotel with a prominent 'aloft' sign, a 'WXYZ' sign, and a 'Coming Soon' advertisement on the side.

8. Aloft by Marriott St Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Jacob

AED 418

AED 489 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

A hotel room with a bed, a pink sofa, a small table, and a chair. There is a window with a view of a building.

A modern indoor seating area with a sofa, tables, and chairs.

A hotel coffee shop with a coffee machine, mugs, and a buffet area.

9. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 0.9 km from St. Louis Science Center

paullita jeanne

AED 571

AED 668 total

includes taxes & fees

4 Oct - 5 Oct

A spacious foyer with a grand staircase, a piano, and a large rug.

A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

10. White House at Grand Central

3 km from St. Louis Science Center

Triman

AED 310

AED 492 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

A spacious lobby with leather sofas, a patterned rug, and a reception desk.

A hotel room with a sofa, a blue armchair, a desk with a computer, a TV, and a bed.

A modern kitchen with wooden cabinets, a central island, and a wall display of packaged goods.

11. DoubleTree by Hilton St. Louis Forest Park

Central West End, 1.3 km from St. Louis Science Center

Kevin

AED 561

AED 661 total

includes taxes & fees

12 Oct - 13 Oct

A bedroom with a large bed, a mirror, and a vanity with shelves.

A wall with a large, abstract mirror design.

A room with a grand piano, a round table with a red and white tablecloth, and a statue of a robed figure.

A bedroom with a bed, a mirror, a dresser, and a chandelier.

12. Central West End B&B

Central West End, 3 km from St. Louis Science Center

Stacee

AED 562

AED 711 total

includes taxes & fees

7 Oct - 8 Oct

A hotel room with two beds, a chair, a desk, and a large window.

A bathroom with a bathtub, toilet, and sink.

A conference room with a floral carpet, tables with chairs, and a large orange pendant light.

A reception desk with a sign reading "Forest Park Hotel" and a clock on the wall.

13. Forest Park Hotel by MDR

The Hill, 1.8 km from St. Louis Science Center

Janice

AED 284

AED 349 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a desk, a television, a bed, a mirror, and a coffee maker.

A reception area with a counter, a clock, and a sign indicating free Wi-Fi availability.

A Red Roof Plus hotel lobby with two leather chairs, a coffee station, and a sign indicating free Wi-Fi in all rooms.

A Red Roof Plus hotel with a stone facade, a parking lot, and a covered outdoor area.

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

The Hill, 1.8 km from St. Louis Science Center

Sean

AED 276

AED 322 total

includes taxes & fees

4 Oct - 5 Oct

A room with a green armchair, a round table, a lamp, and a mirror on the wall.

A two-story building with a dark entrance, large windows, and a brick facade.

A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

15. Truitt Hotel

Lafayette Square, 4.9 km from St. Louis Science Center

Gabrielle

AED 691

AED 835 total

includes taxes & fees

4 Oct - 5 Oct

A rooftop terrace with wicker furniture, offering a city view.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.

A hotel room with a large window offering a view of the Gateway Arch and a modern building.

16. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 7.1 km from St. Louis Science Center

Salvatore

AED 496

AED 580 total

includes taxes & fees

5 Oct - 6 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

17. Drury Plaza Hotel St. Louis Brentwood

6.5 km from St. Louis Science Center

Janell

AED 499

AED 593 total

includes taxes & fees

11 Oct - 12 Oct

A log cabin with a stone chimney, wooden deck, and a staircase leading to the entrance.

A rustic wooden bed with a quilt, a chair, and a view of the outdoors through a door.

A stone fireplace with a wooden mantel, surrounded by rustic decor and a wooden ceiling.

A cozy bedroom with a stone fireplace, a bed with a patterned bedspread, and a television on a wooden stand.

18. The Lodge at Grant's Trail

10.1 km from St. Louis Science Center

Patricia

AED 646

AED 742 total

includes taxes & fees

5 Oct - 6 Oct

A modern hotel lobby with a glass facade, seating area, and a staircase.

A couple relaxing by a window overlooking a bridge and water.

A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

19. Four Seasons Hotel St Louis

7.5 km from St. Louis Science Center

Nicole

AED 1,377

AED 1,611 total

includes taxes & fees

4 Oct - 5 Oct

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

A restaurant with tables set for dining, a kitchen in the background, and hanging light fixtures.

A modern living room with a sofa, coffee table, and bookshelves.

A modern bar area with a central fire feature, bar stools, and seating.

20. Live by Loews - St.Louis

Downtown St. Louis, 6.7 km from St. Louis Science Center

Molly

AED 584

AED 695 total

includes taxes & fees

4 Oct - 5 Oct

View all properties

Compare popular hotels close to St. Louis Science Center

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Forest Park	9.4 Exceptional 1,017 reviews	View
Hampton Inn & Suites St. Louis at Forest Park	9.4 Exceptional 1,000 reviews	View
The Royal Sonesta Chase Park Plaza St. Louis	9.2 Wonderful 1,016 reviews	View
AC Hotel St. Louis Central West End	9.0 Wonderful 853 reviews	View
Element by Marriott St. Louis Midtown	8.8 Excellent 829 reviews	View

Top St. Louis Science Center Hotel Reviews

DoubleTree by Hilton St. Louis Forest Park

8/10 Good

"clean room"

The West End

10/10 Excellent

"The West End was exactly what I needed. An economical hotel in a great location. The lighting was not the best and I could have used a couple of more clothes hangers, but otherwise it had everything I needed for my stay in St. Louis."

Hotel Indigo St Louis - Central West End by IHG

10/10 Excellent

"I loved how comfortable the bed was, our cute little balcony, oh the shower!!So great and the tv was just right for Monday night football!! The bar downstairs was a bonus too"

Hampton Inn & Suites St. Louis at Forest Park

8/10 Good

"Great stay! Clean, safe hotel in a great location. Helpful staff and good breakfast! We'll stay again!!"

Cielo Casa on “The Hill” Walkable and mins away from, BJC, SLU, Downtown + more

10/10 Excellent

"We loved our stay! This home had everything we needed, including a private fenced-in yard. The location was perfect—within walking distance of The Hill and just a quick drive to the Arch and Forest Park. The home was comfortable, convenient, and in a great location. We would definitely stay here again!"

Forest Park Hotel by MDR

8/10 Good

"I was only there to sleep and did not use any of the amenities. The noise from the highway and the trains was louder than at most hotels I have stayed at."

beautiful small house

10/10 Excellent

"The house was very nice and super clean and had everything you need and the neighborhood was super quiet. Maria was extremely nice and was very prompt on assisting us with any questions we had. The house is also located with everything close by and only 11 mins from downtown St. Louis. I will definitely stay again next time im in the area. And will definitely suggest to anyone i know headed to the area. Much better than any hotel. BIG THANKS MARIA."

4BR Near Forest Park Zoo & Missouri Botanical Garden | Free Parking | STL

10/10 Excellent

"We had a wonderful time. We were here for a wedding at the Wild Carrot and a pre wedding picnic at Tower Grove park so the location is perfect. We walked to the Science Center. Beds were comfortable and plentiful. I loved having plenty of towels available for all of us. The kitchen had all the dishes, etc that we needed. Everything was clean and inviting. If we are ever back in St. Louis, we certainly would choose this house again. Thank you for helping make our stay comfortable!"

Casa Esma on The Hill - Luxury Couples Retreat w/ Private Hot Tub

10/10 Excellent

"Centralized location with plenty of room and a fenced yard for your furry friends. Close to the hill and walking distance to some amazing restaurants. Host was very responsive and had plenty of ideas for our first visit to the area. Quick drive to the arch and downtown as well union Station and other attractions."

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Explore the great outdoors at Jewel Box, a lovely green space in St. Louis. Amble around the area's lush forest or attend a sporting event.

See properties

A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

After visiting Forest Park, make a plan to see the other sights and activities in St. Louis. Discover the area's entertainment choices and shops.

See properties

A gazebo with columns and a dome roof, surrounded by a pond and greenery.

Pagoda Circle

You can spend an afternoon browsing the exhibits at Pagoda Circle during your trip to St. Louis. Experience the area's fascinating museums or attend a sporting event.

See properties

A theater stage with a variety of neon signs advertising different businesses.

The Muny Theater

8.6/10 (7 reviews)

You can enjoy a show at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event.

See properties

Highlands Golf & Tennis Center

Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's entertainment choices or attend a baseball game.

See properties

Atomic Cowboy

Atomic Cowboy is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

See properties

Atomic by Jamo

Atomic by Jamo is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

See properties

Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, check out the 74 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near St. Louis Science Center?

Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good options within a short distance include Home2 Suites by Hilton St. Louis/Forest Park and DoubleTree by Hilton St. Louis Forest Park.

How many hotels will I be able to find near St. Louis Science Center?

Expedia has 74 hotels and other accommodations within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available near St. Louis Science Center.

Where can I learn more about changing or cancelling my trip in the area near St. Louis Science Center?

To access more information about changing or cancelling your stay near St. Louis Science Center, go to https://www.expedia.com/service/.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, St. Louis Art Museum, and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box, and Cherokee Street are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater, and St. Louis Symphony Orchestra.

Find hotels near St. Louis Science Center, St. Louis from AED 322

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Louis Science Center hotels

1. Drury Inn & Suites St. Louis Forest Park

2. Hampton Inn & Suites St. Louis at Forest Park

3. The Royal Sonesta Chase Park Plaza St. Louis

4. AC Hotel St. Louis Central West End

5. Element by Marriott St. Louis Midtown

6. Hotel Indigo St Louis - Central West End by IHG

7. The West End

8. Aloft by Marriott St Louis Central West End

9. Home2 Suites by Hilton St. Louis/Forest Park

10. White House at Grand Central

11. DoubleTree by Hilton St. Louis Forest Park

12. Central West End B&B

13. Forest Park Hotel by MDR

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

15. Truitt Hotel

16. Drury Plaza Hotel St. Louis at the Arch

17. Drury Plaza Hotel St. Louis Brentwood

18. The Lodge at Grant's Trail

19. Four Seasons Hotel St Louis

20. Live by Loews - St.Louis

Compare popular hotels close to St. Louis Science Center

Top St. Louis Science Center Hotel Reviews

DoubleTree by Hilton St. Louis Forest Park

The West End

Hotel Indigo St Louis - Central West End by IHG

Hampton Inn & Suites St. Louis at Forest Park

Cielo Casa on “The Hill” Walkable and mins away from, BJC, SLU, Downtown + more

Forest Park Hotel by MDR

beautiful small house

4BR Near Forest Park Zoo & Missouri Botanical Garden | Free Parking | STL

Casa Esma on The Hill - Luxury Couples Retreat w/ Private Hot Tub

Other attractions near St. Louis Science Center

Jewel Box

Forest Park

Pagoda Circle

The Muny Theater

Highlands Golf & Tennis Center

Atomic Cowboy

Atomic by Jamo

Frequently asked questions