A tree-lined landscape with a river and fields.

Find hotels in East Prairie, MO from AED 179

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Our top choices for East Prairie hotels

1. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,009 reviews)
"Clean rooms, great parking, very nice staff"
United States
Shelley
The price is AED 267
AED 304 total
includes taxes & fees
7 Dec - 8 Dec
Best Western Plus Sikeston I-55

2. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
United States
Roslyn
The price is AED 404
AED 459 total
includes taxes & fees
19 Nov - 20 Nov
Fairfield Inn & Suites by Marriott Sikeston

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (525 reviews)
"Great place to stay on our way to the Ozarks. Loved the comfy bed!"
United States
Wesley
The price is AED 349
AED 397 total
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express & Suites Sikeston Southwest by IHG

4. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,001 reviews)
"Great place to stay!"
United States
Tiffany
The price is AED 345
AED 397 total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Sikeston, MO

5. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (443 reviews)
"Everything was great clean helpful Everything friendly."
United States
Kathleen
The price is AED 244
AED 273 total
includes taxes & fees
14 Nov - 15 Nov
The Riverstone Hotel Charleston-Sikeston

6. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (831 reviews)
"Very clean property and the staff were very accommodating."
United States
Craig
The price is AED 248
AED 282 total
includes taxes & fees
15 Nov - 16 Nov
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

7. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (32 reviews)
"I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great."
United States
Mark
The price is AED 400
AED 455 total
includes taxes & fees
19 Nov - 20 Nov
TownePlace Suites by Marriott Sikeston

8. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (686 reviews)
"Friendly helpful check in, room was comfortable. we were travelling with our dog and it has a large area to walk him around. excellent Mexican restaurant next door we would definitely stay again"
Canada
Judith
The price is AED 215
AED 241 total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Charleston/Sikeston East MO

9. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.4 out of 10, Good, (1,000 reviews)
"It was clean, the room was nice and roomy, bed was very comfortable. Some things were in need of minor repairs, but nothing major."
United States
Earl
The price is AED 244
AED 278 total
includes taxes & fees
15 Nov - 16 Nov
Days Inn and Suites by Wyndham Sikeston

10. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (658 reviews)
"Great hotel, clean spacious room, good breakfast choice"
United Kingdom
Deborah
The price is AED 372
AED 423 total
includes taxes & fees
19 Nov - 20 Nov
Hampton Inn Sikeston

11. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (322 reviews)
"The room was nice"
United States
Fred
The price is AED 309
AED 352 total
includes taxes & fees
22 Nov - 23 Nov
Comfort Inn & Suites Sikeston I-55

12. Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (164 reviews)
"It was an ok room for the price paid."
United States
Marianne
The price is AED 208
AED 248 total
includes taxes & fees
13 Nov - 14 Nov
Country Yard Inn and Suite

13. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (107 reviews)
"Great"
United States
Jackson
The price is AED 242
AED 271 total
includes taxes & fees
13 Nov - 14 Nov
Eagle Inn Charleston

14. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (82 reviews)
"Got there late and staff was very helpful. Room was clean and comfortable"
United States
Wendy
The price is AED 212
AED 243 total
includes taxes & fees
14 Nov - 15 Nov
Super 8 By Wyndham Marston

15. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (297 reviews)
"Good service,nice stuff and no complaints"
United States
Santiago
The price is AED 258
AED 286 total
includes taxes & fees
4 Dec - 5 Dec
Quality Inn Cairo I-57

16. Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (358 reviews)
"It was the perfect stay."
United States
Kevin
The price is AED 367
AED 436 total
includes taxes & fees
28 Nov - 29 Nov
Holiday Inn Express & Suites Union City by IHG

17. Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (453 reviews)
"Clean room, excellent staff, wonderful breakfast"
United States
Ben
The price is AED 260
AED 309 total
includes taxes & fees
6 Dec - 7 Dec
Sleep Inn at Discovery Park of America

18. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (696 reviews)
"It is a clean place, and we enjoyed our stay"
United States
Laura
The price is AED 213
AED 243 total
includes taxes & fees
18 Nov - 19 Nov
Super 8 by Wyndham Sikeston/Miner Area

19. Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.2 out of 10, Very good, (561 reviews)
"Awesome"
United States
Logan
The price is AED 261
AED 310 total
includes taxes & fees
18 Nov - 19 Nov
Quality Inn Union City US 51

20. MainStay Suites at Discovery Park of America

MainStay Suites at Discovery Park of America
2.5 star property
Union City
8.8 out of 10, Excellent, (47 reviews)
"I absolutely love staying there"
United States
Jamie
The price is AED 369
AED 438 total
includes taxes & fees
28 Nov - 29 Nov
MainStay Suites at Discovery Park of America
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

A tree-lined landscape with a river and fields.

Top East Prairie Hotel Reviews

More cheap stays in East Prairie

Hotels in East Prairie with star-rating

Find out more about East Prairie

Top reasons to visit East Prairie

  • Scenic Trails: East Prairie features beautiful landscapes and trails perfect for hiking and outdoor adventures.
  • Romantic Getaways: Ideal for couples, the town offers charming settings for a cozy getaway.
  • Local History: Explore museums and historical sites that showcase the rich culture of the area.
  • Family-Friendly Parks: Enjoy lush parks that provide great spots for family excursions and picnics.
  • Comfortable Accommodations: A variety of hotels and motels cater to travelers' needs, ensuring a pleasant stay.

Find great hotels near East Prairie

Explore a variety of hotel accommodations in East Prairie, Missouri, ideal for travelers seeking comfort and convenience. Whether you're on a business trip, a family vacation, or traveling with pets, you'll find a range of options, including hotels and motels that cater to your needs. Discover the best hotels in East Prairie with positive reviews to ensure a pleasant stay in this charming town.

  • Days Inn and Suites by Wyndham Sikeston: Situated 17.7km from East Prairie, Days Inn and Suites by Wyndham Sikeston offers a welcoming atmosphere perfect for business travelers and pet owners alike. This hotel is designed with convenience in mind, featuring spacious rooms equipped with essential amenities. Guests can enjoy the comfort of a pet-friendly environment, with specific policies accommodating dogs and cats. The hotel also provides complimentary breakfast, making it easy to start your day off right. With its focus on practicality and comfort, this hotel is an excellent choice for those traveling with furry companions.
  • Drury Inn & Suites Sikeston, MO: Also located 17.7km from East Prairie, Drury Inn & Suites Sikeston, MO is a renowned 3-star hotel that embraces inclusivity, welcoming LGBTQIA travelers with open arms. The hotel boasts a variety of amenities designed for both business and leisure guests, including complimentary hot breakfast and evening snacks. Pet-friendly rooms are available with certain restrictions for dogs and cats, ensuring that your furry friends can join you on your journey. The inviting atmosphere and commitment to exceptional service make this hotel a favorite among travelers seeking comfort and community.
  • Pear Tree Inn Sikeston: Just 17.7km from East Prairie, Pear Tree Inn Sikeston caters to families, business travelers, and pet owners with its warm hospitality and thoughtful amenities. The hotel features family-friendly services, including complimentary cribs for younger guests, making it an ideal choice for those traveling with children. Pets are welcome too, with specific policies for dogs and cats. Guests can enjoy a cozy stay with comfortable accommodations and a complimentary breakfast that caters to all ages. Pear Tree Inn Sikeston strikes a balance between family-friendly warmth and professional service, ensuring a pleasant stay for everyone.

Where to stay near East Prairie

Discover the charm of East Prairie, Missouri, where outdoor enthusiasts and romantic getaways thrive. Just a short drive from Sikeston, explore lush parks and scenic open spaces perfect for family-friendly excursions. Enjoy the warm atmosphere filled with friendly people and delightful shopping experiences. Whether you're fishing, hiking, or simply relaxing, East Prairie offers a serene escape that will leave you refreshed and inspired.

  • Sikeston: Located 20.9km from East Prairie, Sikeston is a vibrant city known for its outdoor and family-friendly experiences. The city attracts visitors year-round, with peak seasons from June to August and December to February. Sikeston offers a variety of recreational areas, shopping centers, and educational venues. Notable attractions include a scenic lake and an event conference venue, making it an ideal spot for both relaxation and activities. Whether you're enjoying a day outdoors or exploring local shops, Sikeston provides a welcoming atmosphere for travelers.
  • Charleston: Just 16.1km away from East Prairie, Charleston is a charming city perfect for those seeking outdoor adventures and captivating scenery. Visitor numbers peak in April and from June to July, with a slight decline from October to December. Charleston boasts numerous recreational areas and shopping centers, alongside educational opportunities. The city is home to beautiful landmarks such as a national state park and various historic sites, offering a glimpse into the area's rich history. Nature enthusiasts and adventure seekers will find plenty to explore in Charleston.
  • Bertrand: Also located 16.1km from East Prairie, Bertrand is a picturesque city that attracts visitors for its outdoor adventures and scenic views. With peak travel periods in April, August, and from December to January, Bertrand offers a wealth of natural beauty. The nearby national park, lush forests, and serene lakes provide ample opportunities for hiking, fishing, and enjoying nature. Bertrand is perfect for those looking to escape the hustle and bustle of city life while immersing themselves in the great outdoors.

Things to do near East Prairie

East Prairie, Missouri, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy scenic trails, a recreational area, and opportunities for skiing. Major attractions include the beautiful landscapes of the prairie and various local tourism experiences that showcase the area's natural beauty. Whether you're looking for adventure or relaxation, East Prairie offers a charming escape for all types of travelers.

Shopping

If you're up for a drive, County Market Place is a shopping center located 49.9km away from East Prairie. This venue offers a blend of city, family, and business vibes, making it a great spot for finding unique gifts and souvenirs during your visit.

Recreation

Experience tranquility at the East Prairie Wellness Center, offering yoga classes and holistic therapies in a calming environment. For outdoor fun, visit the nearby Lake County Park, where you can enjoy fishing, hiking trails, and picnicking amidst nature's beauty.

Adventure

In East Prairie, explore the beautiful landscapes at the nearby Mingo National Wildlife Refuge, ideal for hiking and birdwatching. Experience fishing at the local lakes, or try your hand at kayaking for an exciting adventure on the water, surrounded by nature's beauty.

Nightlife

In East Prairie, the Union City Masquerade Theatre, located 49.9km away, is a fantastic spot for a romantic night out, featuring captivating performances that blend entertainment and culture, perfect for immersing yourself in the local arts scene.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for East Prairie

To save money on your trip to East Prairie, plan your visit between December and February when accommodation prices are lowest. Sundays offer the cheapest stays, while Saturdays are the most expensive. Utilize Expedia’s search tool to compare hotel rates and consider booking a package that includes flights and activities for additional savings. For budget-friendly transportation, walking is a great option since the town is easy to navigate. Look for free activities and local attractions to make the most of your visit without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in East Prairie are December to February, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in East Prairie is Sunday. The most expensive day to stay in East Prairie is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your options based on your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your East Prairie hotel reservation with your flights and activities through an Expedia package.

Find the best attractions in and around East Prairie

East Prairie, Missouri, offers a charming blend of outdoor adventures and cultural experiences perfect for a romantic getaway. Visitors can explore beautiful state parks, delve into local history at museums, or attend events at various venues. The area is ideal for those seeking scenic landscapes and engaging activities, with nearby attractions enhancing your exploration of this quaint town.

  • Big Oak Tree State Park: Experience the grandeur of one of the largest oak trees in the United States in this serene national park. With scenic trails and lush landscapes, it’s perfect for outdoor enthusiasts and those seeking adventure in nature.
  • Central Park: Located 20.9km from East Prairie, this vibrant urban park offers a family-friendly atmosphere with playgrounds, picnic areas, and walking paths. Enjoy a leisurely day surrounded by greenery while soaking up the lively city vibes.
  • Sikeston Depot Museum: Also 20.9km away, this art museum showcases the rich cultural history of the region. Explore fascinating exhibits and learn about local heritage while immersing yourself in the artistic ambiance.

Best time to go to East Prairie

The best time to visit East Prairie can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in East Prairie falls in July, when visitor numbers are moderately high and weather is mostly sunny with light rain. The coolest average temperature in East Prairie falls in January, visitor numbers are moderately high and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January36.3°F (2.4°C)Light RainMostly SunnyModerately HighSlightly Low
February39.4°F (4.1°C)Light RainMostly SunnyAverageSlightly Low
March49.5°F (9.7°C)Light RainMostly SunnyAverageAverage
April58.5°F (14.7°C)Light RainMostly SunnyAverageSlightly High
May68.2°F (20.1°C)Light RainMostly SunnyAverageAverage
June77.0°F (25.0°C)Light RainMostly SunnyModerately HighSlightly High
July79.5°F (26.4°C)Light RainMostly SunnyModerately HighAverage
August77.5°F (25.3°C)Light RainMostly SunnyAverageSlightly High
September72.1°F (22.3°C)Light RainMostly SunnyAverageAverage
October60.8°F (16.0°C)Light RainMostly SunnyModerately LowAverage
November48.6°F (9.2°C)Light RainMostly SunnyModerately LowAverage
December41.2°F (5.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to East Prairie

Traveling to East Prairie, Missouri, is convenient with several nearby airports. Paducah, KY (PAH-Barkley Regional) is 62.8km away, with hotel options like The Respite Bed and Breakfast and Harrah's Metropolis Hotel & Casino located nearby. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is 51.5km from East Prairie, offering accommodations such as the Drury Plaza Hotel and Courtyard by Marriott. Cairo, IL (CIR-Cairo Regional) is the closest, just 33.8km away, with options including Quality Inn and Super 8 by Wyndham. Each airport provides easy access to local hotels, ensuring a comfortable stay for visitors.

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best vacation rentals that East Prairie has to offer?
Duck Hunting, Fishing or Relaxing Family Vacation: Visitors like this East Prairie vacation home rental. It is located on a lake and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
Where can I learn more about changing or cancelling my trip to East Prairie?
To access more information about rescheduling or cancelling your trip to East Prairie, click here.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 36 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Columbus-Belmont State Park and Fort Defiance State Park in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.