Find 4 Star Hotels in Des Peres, MO from AED 356
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Des Peres 4 Star Hotels
Compare Des Peres 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
8.4 out of 10, Very Good, (3668)
The price is AED 400
AED 472 total
includes taxes & fees
1 Jun - 2 Jun

River City Casino & Hotel
River City Casino & Hotel
9.0 out of 10, Wonderful, (1215)
The price is AED 430
AED 554 total
includes taxes & fees
5 Jun - 6 Jun

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1003)
The price is AED 621
AED 787 total
includes taxes & fees
26 May - 27 May

DoubleTree by Hilton St. Louis Airport
DoubleTree by Hilton St. Louis Airport
7.8 out of 10, Good, (727)
The price is AED 356
AED 418 total
includes taxes & fees
26 May - 27 May

Moonrise Hotel
Moonrise Hotel
9.0 out of 10, Wonderful, (1722)
The price is AED 526
AED 625 total
includes taxes & fees
15 Jun - 16 Jun

Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
8.4 out of 10, Very Good, (1002)
The price is AED 434
AED 508 total
includes taxes & fees
30 May - 31 May

Live by Loews - St.Louis
Live by Loews - St.Louis
9.2 out of 10, Wonderful, (1003)
The price is AED 621
AED 738 total
includes taxes & fees
25 May - 26 May

21C Museum Hotel St Louis
21C Museum Hotel St Louis
9.0 out of 10, Wonderful, (1135)
The price is AED 590
AED 708 total
includes taxes & fees
25 May - 26 May
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Des Peres.

Four Seasons Hotel St Louis
999 North Second Street, St. Louis, MO
The price is AED 1,748 per night from May 25 to May 26
AED 1,748
AED 2,044 total
includes taxes & fees
25 May - 26 May
9.4/10 Exceptional! (1,000 reviews)
Still don't see what you're looking for?
See all properties in Des Peres.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Des Peres
Des Peres awaits: its food, sports, parks, and more!

Recent reviews of Des Peres hotels
Recent reviews of Des Peres hotels

Live by Loews - St.Louis
5/5 Excellent
"The staff is great, checking and out is very easy!
Clean and great access to the park. "
A verified traveler stayed at Live by Loews - St.Louis
Posted 1 day ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Des Peres Hotels by Star Rating
Stay near popular Des Peres attractions
- Hotels near Museum of Transportation
- Hotels near Sugar Creek Park
- Hotels near Enterprise Center
- Hotels near Busch Stadium
- Hotels near St. Louis Union Station
- Hotels near St. Louis Zoo
- Hotels near Gateway Arch
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near Barnes Jewish Hospital
- Hotels near Hollywood Casino Amphitheatre
- Hotels near City Museum
- Hotels near Dome at America’s Center
- Hotels near Ameristar Casino St. Charles
- Hotels near Six Flags St. Louis
- Hotels near St. Louis University
- Hotels near Mississippi River
- Hotels near Fox Theater
- Hotels near America's Center Convention Complex
- Hotels near Westport Plaza
More Accommodation Types in Des Peres
Explore more hotels
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Casino Queen Hotel
- Moonrise Hotel
- Ameristar Casino Resort and Spa
- 21C Museum Hotel St Louis
- Renaissance St. Louis Airport Hotel
- Live by Loews - St.Louis
- Drury Inn & Suites St. Louis Union Station
- Marriott St. Louis Grand
- Hilton St. Louis at the Ballpark
- Forest Park Hotel by MDR
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- St. Louis Union Station Hotel, Curio Collection by Hilton
- DoubleTree by Hilton St. Louis Airport
- Hilton Pennywell St. Louis at the Arch
- Wingate by Wyndham St. Louis Airport
- Pear Tree Inn St. Louis Near Union Station
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Embassy Suites by Hilton St. Louis Downtown
- Wingate by Wyndham St. Louis/Fenton Route 66