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Find 5 Star Hotels in Defiance, MO from AED 468

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Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

1335 S Lindbergh Blvd Frontenac MO
The price is AED 479 per night from Jan 4 to Jan 5
AED 479
AED 558 total
4 Jan - 5 January 2026
includes taxes & fees
8.6/10 Excellent! (1,000 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

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A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Defiance?
The amount you pay for a 5-star hotel in Defiance depends on things such as when you want to go and the length of your vacation. Our insider tip for scoring an awesome deal? Use our pricing filters to check out the available hotels for your preferred dates.

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What makes a hotel 5 stars in Defiance?
In Defiance, a hotel must provide a specific number of upscale conveniences to earn 5 stars. These can include gourmet restaurants, on-site gyms, saunas and spas, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding standard of service. You can look forward to things like in-room massages, nightly turn-down services and concierge services. Some may even offer extra touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Defiance?
Our handy filters are the best way to find exactly what you're looking for. Check the "All inclusive" and "5-star" boxes to see the most upscale resorts in Defiance where your accommodations, meals, entertainment and activities are included in the upfront price. At these escapes, your trip is pure relaxation and indulgence from the moment you pull up to the entrance.

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