Find 5 Star Hotels in San Miguelito from AED 444

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Miguelito 5 Star Hotels

Our top choices for San Miguelito 5-star hotels

Outdoor pool, sun loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4654)
"Awesome great place to stay "
United States
Herbert
The price is AED 471
AED 518 total
includes taxes & fees
15 Dec - 16 Dec
Hotel Riu Plaza Panama
2 bars/lounges, poolside bar
Waldorf Astoria Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1001)
"I loved everything about my stay "
United States
Stephanie
The price is AED 810
AED 891 total
includes taxes & fees
3 Jan - 4 January 2026
Waldorf Astoria Panama
2 restaurants, local cuisine
W Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1002)
"It is a hotel with very comfortable and nicely designed rooms in the heart of Panama City. The hotel staff is efficient, attentive and friendly."
United States
SVETLANA
The price is AED 796
AED 876 total
includes taxes & fees
11 Jan - 12 January 2026
W Panama
4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1004)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is AED 955
AED 1,051 total
includes taxes & fees
4 Jan - 5 January 2026
JW Marriott Panama
Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (555)
"Great hotel and location "
United Kingdom
Russell
The price is AED 1,372
AED 1,509 total
includes taxes & fees
15 Dec - 16 Dec
Sofitel Legend Casco Viejo, Panama City
Sports facility
Hilton Panama

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1000)
"Great place to stay."
United States
Salvador
The price is AED 684
AED 752 total
includes taxes & fees
2 Jan - 3 January 2026
Hilton Panama
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1002)
"Our stay was very nice, the service the hotel provides is wonderful, I highly recommend it"
United States
Mayra Alexandra Montes
The price is AED 731
AED 804 total
includes taxes & fees
15 Dec - 16 Dec
The Westin Playa Bonita Panama
40-inch Smart TV with cable channels, TV
Renaissance Panama City Hotel

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (95)
"Great location and amazing staff"
United States
Aziz
The price is AED 426
AED 469 total
includes taxes & fees
19 Dec - 20 Dec
Renaissance Panama City Hotel
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1002)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is AED 809
AED 889 total
includes taxes & fees
20 Dec - 21 Dec
Bristol Panama, a Registry Collection Hotel
View from property
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (638)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is AED 851
AED 936 total
includes taxes & fees
14 Dec - 15 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
View from property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very Good, (1000)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Lobby
Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1000)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Miguelito.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
The price is AED 404 per night from Dec 18 to Dec 19
AED 404
AED 444 total
18 Dec - 19 Dec
includes taxes & fees
8.4/10 Very Good! (2,315 reviews)
Still don't see what you're looking for?
See all properties in San Miguelito.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about San Miguelito

Escape to San Miguelito! Enjoy its food and gardens.

See all hotels in San Miguelito
Amaneceres y Atardeceres en diferentes puntos de la ciudad de panama

Top San Miguelito Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Everything was amazing"
shalena 7-night trip
Posted 1 day ago
Hotel Riu Plaza Panama

Frequently asked questions

What are the best 5-star hotels in San Miguelito?
Based on Expedia traveler reviews, The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City, JW Marriott Panama and The Bahia Grand Hotel are some of the most popular 5-star hotels in San Miguelito. Offering top-of-the-line amenities and unmatchable service, you can expect an opulent and comfortable stay.
How much does it cost to stay in a 5-star hotel in San Miguelito?
You'll find a variety of pricing options for 5-star hotels in San Miguelito on Expedia. The amount you pay will depend on when you plan to travel, trip length and other factors. Compare available accommodations for your preferred dates and use our pricing and other filters to land the perfect high-end stay.

  • Search for the lowest price per night from AED 444

What makes a hotel 5 stars in San Miguelito?
From high-end dining venues and 24/7 fitness centers to swimming pools and deluxe bedding, the 5-star experience in San Miguelito is all about comfort and luxury. But it requires more than just upscale conveniences to get a 5-star rating. Stays must also deliver extraordinary services like in-room massage treatments, laundry and dry cleaning and 24/7 room service.

Explore a world of travel with Expedia