A cityscape with a variety of skyscrapers, including a tall, pointed building and a cylindrical structure.

Find Business Hotels in Buffalo, NY

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Buffalo Business Hotels

Tonight
5 Oct - 6 Oct
Tomorrow
6 Oct - 7 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Buffalo business-friendly hotels

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.
A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.
A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.
A multi-story hotel with a modern facade, large windows, and a covered entrance area.

1. Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
Downtown Buffalo
United States
Julian
AED 579
AED 675 total
includes taxes & fees
11 Oct - 12 Oct
Wyndham Garden Buffalo Downtown
A buffet setup with various food items and utensils.
A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".
A hotel room with a sofa, a bed, a desk, and a chair. There are lamps on the desk and bedside tables.
A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

2. Salvatores Grand Hotel

Salvatores Grand Hotel
Buffalo
United States
Margaret
AED 621
AED 706 total
includes taxes & fees
6 Oct - 7 Oct
Salvatores Grand Hotel
An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.
A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.
A Starbucks coffee shop with a modern design, featuring wooden furniture and a spacious layout.
A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

3. Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center
Downtown Buffalo
Canada
Joseph
AED 503
AED 587 total
includes taxes & fees
25 Oct - 26 Oct
Hyatt Regency Buffalo / Hotel and Conference Center
A parking lot with cars and a covered walkway.
An indoor swimming pool with clear glass ceilings, tiled floors, and multiple windows offering views of the outdoors.
A hotel room with a bed, a desk, a sofa, and a painting on the wall.
Exterior

4. Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst
Buffalo
United States
Samuel
AED 577
AED 656 total
includes taxes & fees
4 Nov - 5 Nov
Hyatt Place Buffalo/Amherst
A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.
A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.
A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.
A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

5. Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside
Downtown Buffalo
Canada
Diana
AED 840
AED 980 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard Buffalo Downtown / Canalside
A hotel room with a bed, a TV, a desk, a chair, and a sofa.
A gym with exercise equipment, a mirror, and a television.
A brick building with a storefront labeled 'FRIDAYS' and a green sign with a white 'H' indicating a Holiday Inn Express & Suites.
A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

6. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
Downtown Buffalo
United States
Michael
AED 481
AED 562 total
includes taxes & fees
15 Oct - 16 Oct
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
A hotel with a modern design, featuring a prominent 'La Quinta' sign, multiple windows, and a parking lot with several vehicles.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A hotel room with a large bed, two armchairs, a desk, and a lamp.
A modern restaurant with teal and yellow seating, a flat-screen TV, and a chandelier.

7. La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst
Buffalo
United States
Abhishek
AED 375
AED 426 total
includes taxes & fees
2 Nov - 3 Nov
La Quinta Inn & Suites by Wyndham Buffalo Amherst
An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.
A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.
A lobby area with a reception desk, seating arrangements, a coffee station with beverages and snacks, and a decorative wall with a fireplace.
The exterior of the Hilton Garden Inn, featuring a prominent entrance with a large sign, a flag, and a well-maintained sidewalk.

8. Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown
Downtown Buffalo
United States
Mercedes
AED 590
AED 689 total
includes taxes & fees
11 Oct - 12 Oct
Hilton Garden Inn Buffalo Downtown
A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.
A modern bar area with a curved counter, leather bar stools, and a large chandelier.
Lobby
A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

9. Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
Downtown Buffalo
United States
Janet
AED 965
AED 1,126 total
includes taxes & fees
3 Nov - 4 Nov
Curtiss Hotel, an Ascend Collection Hotel
A hotel room with a bed, a sofa, a desk with a chair, a television, and a minibar.
A spacious dining area with multiple wooden tables and chairs, a kitchen area with a counter and appliances, and a tiled ceiling with a grid pattern.
A spacious lobby with a staircase, a reception desk, and a vending machine.
A Sleep Inn & Suites hotel with a modern design, featuring a prominent entrance, a covered walkway, and a well-maintained lawn.

10. Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport
Buffalo
United States
Ronald
AED 242
AED 275 total
includes taxes & fees
3 Nov - 4 Nov
Sleep Inn & Suites Buffalo Airport
View all properties

Top Buffalo Hotel Reviews

M Hotel Buffalo

M Hotel Buffalo

10/10 Excellent
"Always a Excellent Experence with the staff at the M Hotel . Location is center to Shopping and a Qwick Trip to Highmark Stadium .. Rooms are always clean ,but bathrooms are Dated and need to be Replaced .. Front Desk Staff are 5 Star .."
Philip 1-night trip
Posted 1 hour ago
M Hotel Buffalo
Buffalo Airport Hotel

Buffalo Airport Hotel

8/10 Good
"Staff was friendly and helpful! We enjoyed Wingnutz restaurant/sports bar connected to the hotel. The option of airport shuttle is fantastic!"
Judy 1-night trip
Posted 5 hours ago
Buffalo Airport Hotel
Comfort Inn University

Comfort Inn University

8/10 Good
"Overall, a good comfortable stay…only issue was our safe didnt work…clean room"
Anthony 2-night trip
Posted 6 hours ago
Comfort Inn University
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

8/10 Good
"Shuttle service was good. Breakfast fine. Good for price"
Robyn 1-night trip
Posted 7 hours ago
Sleep Inn & Suites Buffalo Airport
The Richardson Hotel

The Richardson Hotel

10/10 Excellent
"Location was perfect. Near Elmwood Village, where we could walk to. The hotels architecture was beautiful!! Enjoyed watching the history in the museum."
Maria 4-night trip
Posted 14 hours ago
The Richardson Hotel
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

8/10 Good
"Great value nice clean hotel."
Larry 1-night trip
Posted 2 days ago
La Quinta Inn by Wyndham Buffalo Airport
Motel 6 Amherst, NY - Buffalo

Motel 6 Amherst, NY - Buffalo

8/10 Good
"Everything was good except for one thing: the toilet paper roll was definitely NOT reachable from the toilet! What were they thinking? I resorted to using the spare roll and placing it on the edge of the tub. Really, folks?"
Judith 2-night trip
Posted 3 days ago
Motel 6 Amherst, NY - Buffalo
Studio 6 Corporate Extended Stay Buffalo Amherst NY

Studio 6 Corporate Extended Stay Buffalo Amherst NY

10/10 Excellent
"Staff"
Joan 1-night trip
Posted 8 days ago
Studio 6 Corporate Extended Stay Buffalo Amherst NY

Explore a world of travel with Expedia