A cityscape with a variety of skyscrapers, including a tall, pointed building and a cylindrical structure.

Find Business Hotels in Buffalo, NY

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Buffalo Business Hotels

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Buffalo business-friendly hotels

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.
A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.
A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.
A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

1. Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
Downtown Buffalo
United States
Julian
AED 579
AED 675 total
includes taxes & fees
11 Oct - 12 Oct
Wyndham Garden Buffalo Downtown
A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.
A modern lobby with a seating area, a fireplace, and a large window offering a view of the city.
A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.
A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

2. Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside
Downtown Buffalo
Canada
Diana
AED 746
AED 871 total
includes taxes & fees
12 Oct - 13 Oct
Courtyard Buffalo Downtown / Canalside
A buffet setup with various food items and utensils.
A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.
A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".
A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

3. Salvatores Grand Hotel

Salvatores Grand Hotel
Buffalo
United States
Margaret
AED 621
AED 706 total
includes taxes & fees
12 Oct - 13 Oct
Salvatores Grand Hotel
A patio area with outdoor seating, a barbecue grill, and a stone wall.
A multi-story hotel with a modern design, featuring a prominent 'HOME 2' sign, a 'tru' logo, and a well-lit entrance.
A modern hotel lobby with a central seating area, a reception desk, and a colorful mural.
A modern lounge area with seating, tables, and hanging chairs.

4. Tru by Hilton Williamsville Buffalo Airport

Tru by Hilton Williamsville Buffalo Airport
Buffalo
United States
Lachelle
AED 465
AED 529 total
includes taxes & fees
25 Oct - 26 Oct
Tru by Hilton Williamsville Buffalo Airport
A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.
An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.
A hotel room with a sofa, a desk, a chair, a television, and a large mirror.
A modern living room with a fireplace, comfortable seating, and a herringbone-patterned wall.

5. Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
Downtown Buffalo
United States
Gerald D
AED 621
AED 725 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Buffalo Downtown
An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.
A Starbucks coffee shop with a modern design, featuring wooden furniture and a spacious layout.
A hotel room with a sofa set, a small coffee table, a TV, and a lamp.
A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

6. Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center
Downtown Buffalo
Canada
Joseph
AED 503
AED 587 total
includes taxes & fees
25 Oct - 26 Oct
Hyatt Regency Buffalo / Hotel and Conference Center
A parking lot with cars and a covered walkway.
An indoor swimming pool with clear glass ceilings, tiled floors, and multiple windows offering views of the outdoors.
A Hyatt Place hotel with a modern facade, a well-lit entrance, and a parking lot.
A hotel room with a bed, a desk, a sofa, and a painting on the wall.

7. Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst
Buffalo
United States
Samuel
AED 551
AED 627 total
includes taxes & fees
3 Nov - 4 Nov
Hyatt Place Buffalo/Amherst
A modern hotel room with a large window, a sofa, a coffee table, and a TV.
A modern kitchen with a central island, bar stools, and built-in appliances.
A modern hotel lobby with a reception desk, seating area, and a large window offering a view of the city.
A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

8. Buffalo Marriott at LECOM HARBORCENTER

Buffalo Marriott at LECOM HARBORCENTER
Downtown Buffalo
United States
Vincent
AED 889
AED 1,038 total
includes taxes & fees
18 Oct - 19 Oct
Buffalo Marriott at LECOM HARBORCENTER
A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.
A modern hotel room with a dining area, a large bed, and a view of the city.
A modern bar area with seating, a counter with bottles, and a large window.
A hotel room with a large bed, a TV mounted on the wall, a city view through the window, and a wooden shelf.

9. Embassy Suites Buffalo

Embassy Suites Buffalo
Downtown Buffalo
United States
Michelle
AED 653
AED 762 total
includes taxes & fees
18 Oct - 19 Oct
Embassy Suites Buffalo
A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.
A living room with a red wall, white furniture, a fireplace, and a large abstract painting.
A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.
A pool table in a room with dark walls, large windows, and green upholstered chairs.

10. The Mansion On Delaware Ave

The Mansion On Delaware Ave
Downtown Buffalo
United States
Marilyn
AED 724
AED 831 total
includes taxes & fees
18 Oct - 19 Oct
The Mansion On Delaware Ave
View all properties

Top Buffalo Hotel Reviews

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

10/10 Excellent
"Exelwnte"
Yesenia Velez 1-night trip
Posted 2 hours ago
Sleep Inn & Suites Buffalo Airport
The Richardson Hotel

The Richardson Hotel

10/10 Excellent
"This is very unique stay in Buffalo. It is located within walking distance two The Burchfield Penny Art Center and the Buffalo AKG. The historic context of this building was fascinating, and the room was very comfortable. A great stay!"
Scott 1-night trip
Posted 2 hours ago
The Richardson Hotel
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

10/10 Excellent
"Very nice and attentive staff. especially the front desk."
Audrey 1-night trip
Posted 3 hours ago
Hyatt Regency Buffalo / Hotel and Conference Center
Garden Place Hotel

Garden Place Hotel

8/10 Good
"It was simple to access and find your room. The shower head in the bathroom kept making a dripping noise even though it was off. But overall experience was great."
Reginald 3-night trip
Posted 5 hours ago
Garden Place Hotel
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

8/10 Good
"Friendly staff, centrually located. I would stay there again."
Charles 4-night trip
Posted 5 hours ago
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

10/10 Excellent
"Breakfast was better than expected."
Rusty 1-night trip
Posted 18 hours ago
La Quinta Inn by Wyndham Buffalo Airport
Fairbridge Inn Express Buffalo Airport Williamsville

Fairbridge Inn Express Buffalo Airport Williamsville

8/10 Good
"Needs a little TLC but the location is good and the price is right."
Brian 2-night trip
Posted 2 days ago
Fairbridge Inn Express Buffalo Airport Williamsville
Comfort Inn University

Comfort Inn University

10/10 Excellent
"Clean and nice staff."
Brenda 1-night trip
Posted 3 days ago
Comfort Inn University
Studio 6 Corporate Extended Stay Buffalo Amherst NY

Studio 6 Corporate Extended Stay Buffalo Amherst NY

10/10 Excellent
"Staff"
Joan 1-night trip
Posted 12 days ago
Studio 6 Corporate Extended Stay Buffalo Amherst NY

Explore a world of travel with Expedia