The Best Business Hotels in Buffalo, NY from AED 255 in 2026 | Expedia

A cityscape with a variety of skyscrapers, including a tall, pointed building and a cylindrical structure.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Buffalo Business Hotels

Tonight

15 Oct - 16 Oct

Tomorrow

16 Oct - 17 Oct

This weekend

16 Oct - 18 Oct

Next weekend

23 Oct - 25 Oct

Our top choices for Buffalo business-friendly hotels

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

1. Wyndham Garden Buffalo Downtown

Downtown Buffalo

United States

Julian

AED 579

AED 675 total

includes taxes & fees

18 Oct - 19 Oct

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

A modern lobby with a seating area, a fireplace, and a large window offering a view of the city.

2. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo

Canada

Diana

AED 746

AED 871 total

includes taxes & fees

8 Nov - 9 Nov

A parking lot with cars and a covered walkway.

An indoor swimming pool with clear glass ceilings, tiled floors, and multiple windows offering views of the outdoors.

A hotel room with a bed, a desk, a sofa, and a painting on the wall.

Exterior

3. Hyatt Place Buffalo/Amherst

Buffalo

United States

Margie

AED 529

AED 602 total

includes taxes & fees

8 Nov - 9 Nov

A buffet setup with various food items and utensils.

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

4. Salvatores Grand Hotel

Buffalo

United States

Margaret

AED 621

AED 706 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A hotel lobby with seating areas, a reception desk, and large windows overlooking the street.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

A gym with exercise equipment, a mirror, and a television.

5. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Downtown Buffalo

United States

Charles

AED 566

AED 660 total

includes taxes & fees

25 Oct - 26 Oct

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

A pool table in a room with patterned carpet, a dining table with chairs, and a red sofa.

6. The Mansion On Delaware Ave

Downtown Buffalo

United States

Marilyn

AED 724

AED 831 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.

A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

7. Hyatt Regency Buffalo / Hotel and Conference Center

Downtown Buffalo

Canada

Joseph

AED 559

AED 652 total

includes taxes & fees

25 Oct - 26 Oct

A hotel with a modern design, featuring a prominent 'La Quinta' sign, multiple windows, and a parking lot with several vehicles.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A hotel room with a large bed, two armchairs, a desk, and a lamp.

A hotel reception area with a large mural of a lighthouse, a reception desk, and a snack bar with shelves of snacks.

8. La Quinta Inn & Suites by Wyndham Buffalo Amherst

Buffalo

United States

Abhishek

AED 372

AED 423 total

includes taxes & fees

4 Nov - 5 Nov

View all properties

Top Buffalo Hotel Reviews

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

8/10 Good

"Conveniently close to airport and they provide 24/7 airport shuttles free. The breakfast in the morning operates as early as 4:30am until 9:30am/10:30am. 24/7 coffee tea bar. Rooms were very spacious and did the job"

Comfort Inn University

Comfort Inn University

10/10 Excellent

"Good place to stay"

M Hotel Buffalo

M Hotel Buffalo

10/10 Excellent

"Friendly Staff, loaded breakfast"

Quality Inn Near Walden Galleria Mall

Quality Inn Near Walden Galleria Mall

10/10 Excellent

"The location is very convenient!"

The Richardson Hotel

The Richardson Hotel

10/10 Excellent

"The front reception staff was so warm and welcoming each time we entered the hotel."

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

8/10 Good

"The room was clean and the breakfast was great."

Garden Place Hotel

Garden Place Hotel

10/10 Excellent

"Very nice hotel overall."

La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

10/10 Excellent

"Le dije al muchacho que limpiara el cuarto y me cambiara toallas no lo hizo"

Fairbridge Inn Express Buffalo Airport Williamsville

Fairbridge Inn Express Buffalo Airport Williamsville

10/10 Excellent

"Rooms were clean and the property was quiet and tidy."

Explore a world of travel with Expedia

Flights from Buffalo