Find Resorts & Hotels with Spas in Grand Center, MO

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Grand Center Resorts & Hotels with Spas

Top Grand Center Resorts & Hotels with Spas

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very Good, (1001)
"Beautiful hotel, spacious guestroom, comfortable beds, kind and helpful staff! "
United States
Heather
The price is AED 555
AED 710 total
includes taxes & fees
1 Dec - 2 Dec
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1468)
"Great staff and clean room"
United States
Chris
The price is AED 526
AED 633 total
includes taxes & fees
26 Nov - 27 Nov
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1001)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is AED 1,561
AED 1,825 total
includes taxes & fees
22 Nov - 23 Nov
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5.0 star property
Clayton
9.2 out of 10, Wonderful, (551)
"Service is exceptional!!!"
United States
Jorge
The price is AED 1,833
AED 2,140 total
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Grand Center Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Room upgrade without cost was a wonderful suprise. The staff was very helpful and appreciated the no validation ticket for parking this time 🙂"
James 1-night trip
Posted 1 day ago
Clayton Plaza Hotel & Extended Stay

Explore a world of travel with Expedia

Frequently asked questions

Looking to vacation at a spa hotel in Grand Center?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the theater scene and opera in Grand Center—your cultural tour starts here. Take in the culture at the art galleries and churches during your stay. Spa hotels are a great way to break out of your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Grand Center?
Experience Grand Center and visit Powell Symphony Hall, St. Louis Symphony Orchestra, and Sheldon Concert Hall. If you have spare time during your trip, you might want to make a stop at Fox Theater and Grandel Theater.
What is a Grand Center spa hotel?
Spa hotels in Grand Center have full on-site spas offering services including therapies and a range of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.