Top Guest Houses in St. Charles County in 2026

A bridge over a calm river with a sunset sky.

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Our top choices for St. Charles County guest houses

A bar area with wooden tables, leather seating, and a bar counter.

1. The Inn at Elijah McLeans

Washington

Jonathan

AED 565 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

2. Grand Center Inn

Grand Center

Leon and Janis

AED 737 total

includes taxes & fees

27 Oct - 28 Oct

A modern living room with a brick wall, a sofa, a coffee table, and a TV.

3. Cozy, Fun, and One-Of-A-Kind!

Shaw

Riley C.

AED 529 total

includes taxes & fees

21 Oct - 22 Oct

A building for sale with a storefront, a car parked in front, and a pedestrian crossing sign.

4. The Loft on Main | Steps to Dining & Nightlife

St. Charles Historic District

Jackie R.

A staircase with a wooden handrail and a chandelier.

5. Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast

St. Charles Historic District

Michael C.

A single-story house with a front porch, two chairs, and a small garden area.

6. Charming Home with Country Views

Grafton

Scarlett L.

AED 1,448 total

includes taxes & fees

15 Oct - 16 Oct

A spacious living room with wooden beams, a television, a sofa, and a coffee table.

7. In the center of all Historic Main Street has to offer

Grafton

Janelle C.

AED 2,282 total

includes taxes & fees

15 Oct - 16 Oct

A modern kitchen with dark cabinetry, a central island with bar stools, and a chandelier.

8. Lou Luxe- Speakeasy, EPIC Arcade, Hottub & FirePit

Benton Park West

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Top St. Charles County Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"Check in was easy and staff was very nice. Room was hot and AC was not working well. 2 elevators to accommodate lots of people. Lots of wait time. Amenities were very nice. Hotel overall was very nice but could use a good scrubbing."

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"This hotel is located in a great location, close to the Gateway Arch and the ballpark where the Cardinals play. There were numerous fun restaurants within walking distance, and we felt safe except down by the Old Spaghetti Factory. I would stay in this hotel again and recommend it to others."

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Hotel staff were excellent, friendly, professional and by far the best reason to re-book. The hotel itself was very clean, located near professional buildings/courts and some eateries within walking distance. The room was clean as well and nicely proportioned with some of the best mattresses/bedding I've experienced. Only slight downside was the breakfast bar--the food and choices were ample and very good (especially the made to order omelets and waffles) but the setting was less than clean and rather worn--not in keeping with the rest of the hotel. All in all, a great place to stay and would definitely book again."

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Fullsize Car Rentals in Maryland Heights

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for St. Charles County guest houses

1. The Inn at Elijah McLeans

2. Grand Center Inn

3. Cozy, Fun, and One-Of-A-Kind!

4. The Loft on Main | Steps to Dining & Nightlife

5. Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast

6. Charming Home with Country Views

7. In the center of all Historic Main Street has to offer

8. Lou Luxe- Speakeasy, EPIC Arcade, Hottub & FirePit

9. Rustic Retreats

10. Clean Beautiful Multi Level Loft

Top St. Charles County Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Courtyard by Marriott St. Louis Downtown/Convention Center

21C Museum Hotel St Louis

Pear Tree Inn St. Louis Airport

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Clayton Plaza Hotel & Extended Stay

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis Union Station

Moonrise Hotel

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