Top Santa Lucia Hotels

A modern building with a unique triangular roof and a central spire.

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Compare popular hotels in Santa Lucia

Property	Property class	Guest rating
Giuggiulena Villa	3.0 star property	10.0 Exceptional 132 reviews	View
Nostos rooms & Apartments	3.0 star property	9.0 Wonderful 294 reviews	View
Lakkios	3.0 star property	9.2 Wonderful 80 reviews	View
Hotel Palazzo Cavalieri	4.0 star property	9.0 Wonderful 47 reviews	View
Gymnasium	3.0 star property	8.8 Excellent 43 reviews	View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

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A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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Ancient ruins with a large amphitheater surrounded by trees.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

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An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

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Top Santa Lucia Hotel Reviews

B&B Nike

10/10 Excellent

"The room and bathroom were large and clean. The mattress and sheets were fantastic. The room had air conditioning. The host was there at check in and was easily accessible. The location was great- just outside Ortigia. Parking was easy and close. An overall nice place to stay."

Maniace Boutique Hotel Ortigia UNA Esperienze

10/10 Excellent

"We arrived feeling stressed after the drive to the hotel! The lovely young lady on the front desk welcomed us with a warm Smile and arranged for the bartender to bring us a drink outside so we could soak up the afternoon sun and relax. We were served a delicious aperol. The decor throughout the hotel is very tasteful even the corridors to the room. Clean white walls but a hint of original brickwork showing. Comfy beds, crisp white linen. Lovely toiletries in the bathroom. Everywhere was spotless. Great breakfast and amazing service. Lovely location just opposite the pretty pebbly beach and around the corner from the lovely streets full of restaurants, shops and wonderful architecture. Would definitely return."

Grand Hotel Villa Politi

8/10 Good

"We overall really enjoyed our 3 night stay here, and appreciated the quiet and historic charm of this hotel. It is an incredibly unique peace of property, with an attached historic Latomie that was both beautiful and intriguing—we really wished the hotel had access to explore the areas below. We also really appreciated the continental breakfast, and were surprised by other’s complaints in reviews we had read before staying here. It was the most elaborate continental breakfast we have ever experienced, with options ranging from fresh fruit, to delicious pastries, and even eggs and bacon for those with used to a more American meal. We loved the pool as well, however we were disappointed that it was only open until 7pm every day, we would have enjoyed an evening swim. The bar was also closed, though they provided service through the bar inside. We also really enjoyed the 2 for $22 aperitivo offered from the bar. The room we stayed in was small and a bit dated, but met our expectations for an older hotel. We also had issues with the AC not turning off and making our room very cold. We were able to find parking every night, however I would not describe it as a big parking lot, and it was overflowing every night with people crammed wherever they could find room."

Algila' Ortigia Charme Hotel

10/10 Excellent

"Beautiful hotel with wonderful hospitality We absolutely loved our stay at Hotel Algilà Ortigia Charme. From the moment we arrived, the staff were warm, friendly and genuinely welcoming. The hotel is full of Sicilian character and charm, and its location in Ortigia was perfect for exploring on foot. Our room was comfortable and beautifully suited to the character of the hotel, and the staff were always happy to help with recommendations and anything we needed. After travelling throughout Sicily for two weeks, what stood out most was the genuine hospitality. We felt like valued guests, not just another reservation. Algilà was exactly what we hoped for from a Sicilian hotel — charming, personal and welcoming. We would happily stay here again and highly recommend it to anyone visiting Ortigia!"

Caportigia Boutique Hotel

10/10 Excellent

"Overall the hotel was very nice and in perfect location. We would definitely stay again. Some items they could improve. The reading lights above bed did not work and there was no other source of light except the huge lights for the entire room. The shower floor was super super super slippery. Both my husband and I almost fell several times. It was so bad while mid shower I couldn’t even move because I knew if I went either direction I was going to fall. Being it is so hot, and considering price of rooms they could provide more bottles of water for room. Maybe 4 instead of 2. Our friends stayed in Junior Suite and they didn’t realize it was 2 floors and the bathroom was downstairs. And it was a spiral staircase coming down with no handrail and he just had knee surgery and neck surgery. They wouldn’t have booked room if they knew that. The rooftop area is really nice but be sure to get them to open the sun shade for you because it can get really hot."

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.

Where is the best place to stay in Santa Lucia?

Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.

How many hotels can I expect to find in Santa Lucia?

Expedia has 313 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.

Where can I learn more about changing or cancelling my trip to Santa Lucia?

For more details about changing or cancelling your trip to Santa Lucia, click here.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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Our top choices for Santa Lucia hotels

1. Grande Albergo Alfeo

2. Caportigia Boutique Hotel

3. Nostos rooms & Apartments

4. Hotel Palazzo Cavalieri

5. Fortaleza Charme House

6. Lakkios

7. Melody rooms

8. B&B Nike

9. Giuggiulena Villa

10. Residence Agatocle

11. Gymnasium

12. Piccolo Hotel Casa Mia

13. Regina Margherita

14. B&B IL MORO

15. Calafatari B&B

16. San Nicola Rooms Siracusa

17. Syraka Design Rooms & Suites

18. Re Dionisio Luxury Suites

19. B&B Siracusa

20. Casa Miranda Boutique

Compare popular hotels in Santa Lucia

Where to stay in Santa Lucia

Ortigia

Grottasanta

Neapolis

Tiche

Acradina

Top Santa Lucia Hotel Reviews

B&B Nike

Frequently asked questions