Find 5 Star Hotels in St. Charles, MO from AED 409
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on St. Charles 5 Star Hotels
Compare St. Charles 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Four Seasons Hotel St Louis
Downtown St. Louis
9.4 out of 10, Exceptional, (1004)
The price is AED 1,561
AED 1,825 total
includes taxes & fees
9 Dec - 10 Dec

The Ritz-Carlton, St. Louis
Clayton
9.2 out of 10, Wonderful, (551)
The price is AED 1,723
AED 2,011 total
includes taxes & fees
29 Nov - 30 Nov
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Charles.

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
The price is AED 371 per night from Dec 8 to Dec 9
AED 371
AED 441 total
8 Dec - 9 Dec
includes taxes & fees
8.6/10 Excellent! (1,129 reviews)
Still don't see what you're looking for?
See all properties in St. Charles.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about St. Charles
Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

Top St. Charles Hotel Reviews
Frequently asked questions
Explore a world of travel with Expedia
St. Charles Hotels by Star Rating
Hotels in St. Charles Neighborhoods
Stay near popular St. Charles attractions
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Family Arena
- Hotels near Historic Main Street
- Hotels near Fast Lane Classic Cars
- Hotels near Katy Trail
- Hotels near Missouri Bluffs Golf Course
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Jaycee Park
- Hotels near Missouri Artists on Main
- Hotels near Frenchtown Heritage Museum
- Hotels near Mississippi River
- Hotels near Missouri River
More Hotel Options in St. Charles
- Adventure Hotels in St. Charles
- Business Hotels in St. Charles
- Casinos in St. Charles
- Cheap Hotels in St. Charles
- Family Hotels in St. Charles
- Golf Hotels in St. Charles
- Historic Hotels in St. Charles
- Hotel Wedding Venues in St. Charles
- Hotel with a Concierge in St. Charles
- Hotels with Bars in St. Charles
- Hotels with Free Parking in St. Charles
- Hotels with Hot Tubs in St. Charles
- Hotels with WiFi in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with an Indoor Pool in St. Charles
- Hotels with smoking rooms in St. Charles
- Luxury Hotels in St. Charles
- Pet-friendly Hotels in St. Charles
- Resorts & Hotels with Spas in St. Charles
- Romantic Hotels in St. Charles
- Shopping Hotels in St. Charles
- Winery Hotels in St. Charles
Explore more hotels
- Pear Tree Inn St. Louis Near Union Station
- Clayton Plaza Hotel & Extended Stay
- 21C Museum Hotel St Louis
- Best Western St. Louis-Kirkwood Route 66
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Renaissance St. Louis Airport Hotel
- Pear Tree Inn St. Louis Airport
- Home2 Suites by Hilton St. Louis Downtown
- Live by Loews - St.Louis
- Hollywood Casino & Hotel St. Louis
- DoubleTree by Hilton St. Louis Airport
- St. Louis Airport Hotel
- AC Hotel St. Louis Clayton
- Embassy Suites by Hilton St. Louis Downtown
- DoubleTree by Hilton St. Louis Forest Park
- Marriott St. Louis Grand
- St. Louis Union Station Hotel, Curio Collection by Hilton
- The Wildwood Hotel
- Courtyard by Marriott St. Louis Downtown/Convention Center
- Angad Arts Hotel St. Louis, Tapestry Collection by Hilton








