A multi-directional signpost with various destination names and distances.

Find all hotels by Independent in Lower Keys, FL

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
16 Aug - 17 Aug
Tomorrow
17 Aug - 18 Aug
Next weekend
21 Aug - 23 Aug
In two weeks
28 Aug - 30 Aug
Save an average of 15% on thousands of hotels when you're signed in

Top Lower Keys Hotel Reviews

Looe Key Reef Resort

Looe Key Reef Resort

10/10 Excellent
"Great clean place to stay with a great tiki bar/restaurant/pool and fabulous dive/snorkle center on site with a fabulous crew that takes you to the protected Looe Key Reef. Highly recommend the water trip over anything in Key West,"
Bonita 4-night trip
Posted 9 hours ago
Looe Key Reef Resort
Old Wooden Bridge Resort and Marina

Old Wooden Bridge Resort and Marina

10/10 Excellent
"Love being on the water in the houseboat. The dark skies were nice for stargazing"
Lisa 4-night trip
Posted 1 day ago
Old Wooden Bridge Resort and Marina
Parmer's Resort

Parmer's Resort

8/10 Good
"Property was clean, well-kept, easily accessible with lots of accommodations to choose from: hammocks, kayaks, docks, pool, star-gazing. Though kayaks were only available until 3pm - that seemed way too early to stop enjoying the water. All in all though, we would come back, just better prepared with timing to actually enjoy the water better."
Erin 3-night trip
Posted 3 days ago
Parmer's Resort
Sugarloaf Key RV Resort & Cottages

Sugarloaf Key RV Resort & Cottages

10/10 Excellent
"This facility was clean and beautiful. The "bungalow" was spacious, immaculate, and beautifully maintained. Although we only took advantage of the use of the bungalow, it was superior to staying at a big, name-brand hotel. What a gem!"
Judith 2-night trip
Posted 4 days ago
Sugarloaf Key RV Resort & Cottages
Oceanside Paradise  Free Kayaks Bikes Pool & Hot Tub Tennis & Pickle ball

Oceanside Paradise Free Kayaks Bikes Pool & Hot Tub Tennis & Pickle ball

10/10 Excellent
"We really enjoyed the privacy and safety of the community. We arrived a little early and were able to gain early access. That was not expected. Then we met Julie, who hand delivered us a delicious key-lime pie! Julie was great throughout our whole stay and accommodated all our needs well beyond our expectations. The place was clean, and the kitchen was loaded with everything you would need to prepare dinner/drinks at home. The bikes were a treat. We used them to roam around or when the kids wanted to fish/swim. The balcony is beautiful with a nice sunrise view. The only suggestion i would make is if your'e bringing more then one vehicle, figure out the overflow parking before hand. There is a one vehicle limit that got a bit confusing in the later hours."
Stan R. 3-night trip
Posted 5 days ago
Oceanside Paradise Free Kayaks Bikes Pool & Hot Tub Tennis & Pickle ball
Sunshine Key RV Resort & Marina

Sunshine Key RV Resort & Marina

10/10 Excellent
"Love staying at sunshine key and always rent their cabins. The tiny homes are beautiful and have a great view. The RVs need some upgrading ASAP. The staff is very attentive and accommodating"
Yanet 2-night trip
Posted 7 days ago
Sunshine Key RV Resort & Marina
Cottage with Pool and Dockage, just minutes to Key West

Cottage with Pool and Dockage, just minutes to Key West

10/10 Excellent
"This location is very convenient for me as my family lives 5 miles from this place. Very clean and the host works well with the customer."
Faith H. 2-night trip
Posted 2 weeks ago
Cottage with Pool and Dockage, just minutes to Key West
Springs Venture Out Dolphin House #386 with beautiful open water views

Springs Venture Out Dolphin House #386 with beautiful open water views

10/10 Excellent
"Excellent"
Justin W. 10-night trip
Posted 2 weeks ago
Springs Venture Out Dolphin House #386 with beautiful open water views
Charming 3-bedroom house in 
Big Pine Key near Beach and Key West

Charming 3-bedroom house in Big Pine Key near Beach and Key West

8/10 Good
"The home was accommodating but missing items like hand towels, wash cloths in the bathrooms and oven mitts and drying towels in the kitchen. Better instructions on garbage pick up days. Quiet neighborhood and enjoyed our key deer!"
Pamela K. 4-night trip
Posted 2 weeks ago
Charming 3-bedroom house in Big Pine Key near Beach and Key West

Explore a world of travel with Expedia