A paved pathway lined with tropical plants and palm trees, leading to a gazebo and a fountain.

Find 4 Star Hotels in Sanibel, FL from AEDĀ 2,040

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Sanibel 4 Star Hotels

This weekend
26 Jun - 28 Jun
Next weekend
3 Jul - 5 Jul

Our top choices for Sanibel 4-star hotels

Exterior

Shell Island Beach Club

Shell Island Beach Club
4.0 star property
East End
9.6 out of 10, Exceptional, (24 reviews)
"Very clean. Excellent location, close to beach, walkable to restaurants."
United States
Dawn
Shell Island Beach Club
Premium Cottage, Lanai, Garden View | Living area | Smart TV

Driftwood Inn

Driftwood Inn
4.0 star property
Mid Island
10.0 out of 10, Exceptional, (11 reviews)
"The cottage was well stocked with all we needed. It was also immaculate with a lovely garden. The beach was a 5 minute walk."
United States
Maureen
The price is AEDĀ 1,113
AEDĀ 2,122 total
includes taxes & fees
28 Jun - 29 Jun
Driftwood Inn
Condo (Villa Sanibel 2B) | Exterior

Villa Sanibel 2B

Villa Sanibel 2B
4.0 star property
Mid Island
Villa Sanibel 2B
House (Twin Lakes Home) | Private kitchen

Twin Lakes Home

Twin Lakes Home
4.0 star property
West End
Twin Lakes Home
Condo (Surfside 12 C4) | Living room | Flat-screen TV

Surfside 12 C4

Surfside 12 C4
4.0 star property
East End
Surfside 12 C4
Condo (Blue Gulf 201) | Exterior

Blue Gulf 201

Blue Gulf 201
4.0 star property
West End
Blue Gulf 201
Condo (Shorewood 3B) | Living room | Flat-screen TV, DVD player

Shorewood Condos by Dream Vacation Rentals

Shorewood Condos by Dream Vacation Rentals
4.0 star property
Mid Island
Shorewood Condos by Dream Vacation Rentals
Outdoor pool

Loggerhead Cay by Dream Vacation Rentals

Loggerhead Cay by Dream Vacation Rentals
4.0 star property
Mid Island
Loggerhead Cay by Dream Vacation Rentals
Condo (Spanish Cay B4) | Living room | TV, fireplace

Spanish Cay by Dream Vacation Rentals

Spanish Cay by Dream Vacation Rentals
4.0 star property
Mid Island
Spanish Cay by Dream Vacation Rentals
Balcony

Sanibel Beach Club 2

Sanibel Beach Club 2
4.0 star property
East End
Sanibel Beach Club 2
Condo (Sand Pointe 212) | Pool | Outdoor pool, a heated pool

Sand Pointe 212

Sand Pointe 212
4.0 star property
West End
Sand Pointe 212
Condo (Blind Pass G105) | Exterior

Blind Pass G105

Blind Pass G105
4.0 star property
West End
Blind Pass G105
House (Coconut Palms) | Exterior

Coconut Palms

Coconut Palms
4.0 star property
Mid Island
Coconut Palms
House (Chip Shot) | Exterior

Chip Shot

Chip Shot
4.0 star property
Mid Island
Chip Shot
House (A Peace of Heaven) | Balcony

A Peace of Heaven

A Peace of Heaven
4.0 star property
Mid Island
A Peace of Heaven
Condo | Beach | Beach nearby

D1 2bed/2bath

D1 2bed/2bath
4.0 star property
East End
D1 2bed/2bath
Condo (Compass Point 122) | Balcony

Compass Point 122

Compass Point 122
4.0 star property
Mid Island
Compass Point 122
Condo (A1 2BED/2BATH) | Beach | Beach nearby

A1 2bed/2bath

A1 2bed/2bath
4.0 star property
East End
A1 2bed/2bath
Condo (Pointe Santo A41) | Pool | Outdoor pool, a heated pool

Pointe Santo Condos by Dream Vacation Rentals

Pointe Santo Condos by Dream Vacation Rentals
4.0 star property
Mid Island
Pointe Santo Condos by Dream Vacation Rentals
Condo | Beach | On the beach

H7 1bed/1bath

H7 1bed/1bath
4.0 star property
East End
H7 1bed/1bath
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Sanibel.
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

1451 Middle Gulf Drive Sanibel FL
The price is AEDĀ 1,649 per night from Jun 28 to Jun 29
AEDĀ 1,649
AEDĀ 2,040 total
28 Jun - 29 Jun
includes taxes & fees
8.6/10 Excellent! (2,661 reviews)
Still don't see what you're looking for?
See all properties in Sanibel.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Sanibel

Shell-seekers flock to pristine beaches where the 'Sanibel Stoop' is the local posture for finding perfect specimens. Bike the 25-mile trail network through wildlife refuges where alligators sunbathe and over 245 bird species can be spotted with binoculars.

See all hotels in Sanibel

Top Sanibel Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Sanibel?
Kick back in 4-star hotel comfort at Marriott Sanibel Harbour Resort & Spa. Highly recommended by many Expedia guests, it comes with a sauna and a swimming pool. Also consider Pink Shell Beach Resort and Marina. Beauty services and a resort make this getaway another popular choice in Sanibel.
How much does it cost to stay in a 4-star hotel in Sanibel?
To book a 4-star hotel in Sanibel that's within your budget, use Expedia's sort and search filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also list your results by the cheapest property first.

  • Search for the lowest price from AEDĀ 2,040

What's the difference between 5-star and 4-star hotels in Sanibel?
Treat yourself to luxury during your Sanibel escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are usually filled with amenities like large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and unforgettable one. Round-the-clock concierge assistance, elegant furnishings and gourmet dining are only the start of the first-rate conveniences and services you'll likely get access to.

Explore a world of travel with Expedia