Find Luxury Hotels in Sanibel, FL

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Sanibel Luxury Hotels

Tonight
24 Jun - 25 Jun
Tomorrow
25 Jun - 26 Jun
This weekend
27 Jun - 29 Jun
Next weekend
4 Jul - 6 Jul

Top Sanibel Luxury Hotels

Sundial Beach Resort & Spa
Daily cooked-to-order breakfast for a fee

Sundial Beach Resort & Spa

5.0 star property
8.6 out of 10, Excellent, (2566)
"I enjoyed my stay at the Sundial. It was great to be back in Sanibel."
The price is AED 1,575
AED 2,240 total
includes taxes & fees
6 Jul - 7 Jul
Sundial Beach Resort & Spa
The Ritz-Carlton, Naples
Lobby

The Ritz-Carlton, Naples

5.0 star property
9.2 out of 10, Wonderful, (422)
"It was very nice and quiet"
The price is AED 2,567
AED 3,074 total
includes taxes & fees
6 Jul - 7 Jul
The Ritz-Carlton, Naples
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you looking for a luxury hotel for your stay in Sanibel?
Use Expedia and let us help you arrange a flight to Southwest Florida Intl. Airport (RSW) airport or Punta Gorda Airport (PGD) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Sanibel offers. During your visit, you might want to enjoy the beaches and sunsets which Sanibel is known for.
How many luxury hotels will I find in Sanibel?
Lie in the lap of luxury during your getaway to Sanibel in one of Expedia's 6 luxury hotels.
When can I expect good weather in Sanibel?
Planning for the weather is an important factor for making your trip to Sanibel a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 68°F. The rainiest months in Sanibel are August, September, July, and June, with each month seeing an average of 9 inches of rainfall.
What's there to see and do in Sanibel?
Enjoy all that Sanibel has to offer when you visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have a little extra time during your trip, you might want to check out Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.