Find Resorts & Hotels with Spas in Sanibel, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Sanibel Resorts & Hotels with Spas

Our top choices for Sanibel hotels with a spa

Couples treatment rooms, body treatments, deep-tissue massages

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island
8.6 out of 10, Excellent, (2,618 reviews)
  • cleanliness
    Serene beachfront escape with a full-service spa, tennis courts, and waterfront dining awaits at this coastal retreat.
The price is AED 1,649
AED 2,040 total
includes taxes & fees
14 Apr - 15 Apr
Sundial Beach Resort & Spa
Couples treatment rooms, sauna, steam room, aromatherapy

Shangri-La Springs

Shangri-La Springs
2.5 star property
Bonita Springs
9.2 out of 10, Wonderful, (206 reviews)
  • cleanliness
    Indulge in tranquil luxury at this serene spa retreat with six treatment rooms, private patios, and lush gardens for a rejuvenating escape.
The price is AED 418
AED 466 total
includes taxes & fees
4 May - 5 May
Shangri-La Springs
Massages

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (1,997 reviews)
  • cleanliness
    Indulge in rejuvenating massage treatments at this oceanfront sanctuary with a full-service spa, outdoor pool, and white sand beach.
The price is AED 870
AED 1,155 total
includes taxes & fees
29 Apr - 30 Apr
Margaritaville Beach Resort Fort Myers
Couples treatment rooms, sauna, steam room, body treatments

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
Punta Rassa
8.4 out of 10, Very Good, (1,001 reviews)
  • cleanliness
    Luxuriate in a waterfront resort with 24 treatment rooms offering massages, aromatherapy, and reflexology in a full-service spa retreat.
The price is AED 1,090
AED 1,344 total
includes taxes & fees
30 Apr - 1 May
Marriott Sanibel Harbour Resort & Spa
Suite, 2 Bedrooms, Marina View | Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Refresh at a bayfront sanctuary with 5 treatment rooms, waterfront gardens, and rooftop relaxation spaces perfect for wellness seekers.
The price is AED 577
AED 791 total
includes taxes & fees
27 Apr - 28 Apr
The Westin Cape Coral Resort At Marina Village
Body treatments, aromatherapy, hot stone massages, deep-tissue massages

Hyatt Regency Coconut Point Resort & Spa

Hyatt Regency Coconut Point Resort & Spa
4.5 star property
Bonita Springs
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Retreat to this luxury bayside resort with 18 treatment rooms, four outdoor pools, and deep-tissue massages for a rejuvenating spa escape.
The price is AED 1,484
AED 1,839 total
includes taxes & fees
4 May - 5 May
Hyatt Regency Coconut Point Resort & Spa
View from room

LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort
4.5 star property
Vanderbilt Beach
9.0 out of 10, Wonderful, (999 reviews)
  • cleanliness
    Unwind in paradise at this Naples resort with outdoor spa treatments and private beach access for ultimate rejuvenation.
The price is AED 2,384
AED 2,870 total
includes taxes & fees
3 May - 4 May
LaPlaya Beach & Golf Resort - A Noble House Resort
Couples treatment rooms, sauna, hot tub, steam room, body treatments

The Ritz-Carlton, Naples

The Ritz-Carlton, Naples
5.0 star property
Pelican Bay
9.2 out of 10, Wonderful, (475 reviews)
  • cleanliness
    Luxurious pampering awaits at this beachfront resort with 35 spa treatment rooms and heated pools for complete rejuvenation.
The price is AED 4,037
AED 4,726 total
includes taxes & fees
8 May - 9 May
The Ritz-Carlton, Naples
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Sanibel

Pool
Hot tub

Top Sanibel Hotel Reviews

Casa Ybel Resort

Casa Ybel Resort

8/10 Good
"Nice, quiet, friendly. Spacious unit and pretty beach and pool."
Karrie 6-night trip
Posted 1 day ago
Casa Ybel Resort
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

8/10 Good
"Great resort, and property. Good food, tiki bar, and activities for the kids at the pool. Bikes to rent were fun, and tennis/pickelball was fun to have right on the property. I've stayed here 3 times, and will be back again some day."
Chris Earl 7-night trip
Posted 3 days ago
Sundial Beach Resort & Spa

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in Sanibel?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the beaches in Sanibel. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Sanibel?
Enjoy Sanibel and visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have extra time while you're in the area, you might want to see Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.
What is a Sanibel spa hotel?
Spa hotels in Sanibel provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.