Durham, NC Vacation Homes from AED 238

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Our top choices for Durham vacation homes

An outdoor patio area with a stone wall, wooden fence, and a table set for a meal.

1. Chic Craftsman, Walk Downtown

Downtown Durham

Debby C.

A wooden house entrance with a red door, a mailbox, and a potted plant.

2. Historic Duplex with Patio

Downtown Durham

Jorisis S.

AED 602 total

includes taxes & fees

17 Nov - 18 Nov

A bedroom with a bed, a ceiling fan, a nightstand, a cabinet, and a door.

3. Cozy Bungalow near Duke & Dining, Walkable Area

Durham

Mark B.

AED 961 total

includes taxes & fees

29 Nov - 30 Nov

A wooden deck with a white door leading to a room with a television and a window with blinds.

4. Duke Snuggle Bunker

Durham

Jasper R.

What's more luxurious than velvet + fresh linens? This queen-sized bed features a velvet frame and soft, deep mattress - great for a great night's sleep.

5. Cottage with Yard, Mins to Duke

Durham

Dale C.

A bedroom with a large bed, a patterned rug, a desk with a lamp, and a view of the outside.

6. New & Renovated Charming Bungalow near DT Durham

Trinity Park

Kelsey G.

A two-story house with a balcony, surrounded by a wooden deck and a gravel path.

7. 2BR Urban Retreat, Deck, Near Downtown Durham

Durham

A modern kitchen with a built-in refrigerator, a ceiling fan, and a window with curtains.

8. Guest House with private Gate Near Downtown Durham Peaceful 2-bedroom 2 Bathroom

Durham

Tina J.

AED 1,196 total

includes taxes & fees

11 Dec - 12 Dec

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a marble countertop, and a central island with food and drinks.

9. Spacious Open-Concept Durham Home

Durham

Tammy T.

AED 997 total

includes taxes & fees

17 Nov - 18 Nov

A two-story house with a porch, a brick chimney, and a well-maintained lawn.

10. Historic Craftsman, Walk to Duke

Durham

Kathleen M.

AED 1,049 total

includes taxes & fees

18 Nov - 19 Nov

A modern kitchen with white cabinets, a large island, stainless steel appliances, and a dining area with a table and chairs.

11. COZY SUN FILLED HOME / MODERN VILLA NEAR DOWNTOWN

Durham

Garret P.

AED 1,388 total

includes taxes & fees

19 Nov - 20 Nov

A modern living room with a leather sofa, a coffee table, and a TV on a stand.

12. Duke Hospital House

Durham

Ronnie H.

A dining area with a wooden table and chairs, a white console table with drawers, a flat-screen TV mounted on the wall, and a painting above the table.

13. ★Serine Space ★ King Bed ★ Long Term Stays ★ Duke★

Durham

Brasil F.

AED 1,151 total

includes taxes & fees

12 Nov - 13 Nov

A modern kitchen with stainless steel appliances, a dining table with chairs, and a potted plant.

14. 2 BR King Bed Near Duke Hospital & Campus

Durham

Janet J.

A bedroom with a tufted headboard, patterned wallpaper, a white bedspread, and a bedside table with a lamp.

15. Pool and Games New Modern Home

Hayes

AED 1,313 total

includes taxes & fees

17 Nov - 18 Nov

A house with a porch, a red door, and a mailbox.

16. Vintage Cottage less than 3 mi from Duke Hospital

Forest Hills

Susan Anne Y.

AED 1,334 total

includes taxes & fees

12 Nov - 13 Nov

A modern hotel room with a flat-screen TV mounted on the wall, a dark wooden desk, and a small table with a basket.

17. Stylish and NEW! Duke~Art Deco

Durham

AED 1,229 total

includes taxes & fees

17 Nov - 18 Nov

A living room with a fireplace, leather sofas, a glass coffee table with flowers, and a view through a glass door.

18. Designer Garden Home Downtown

Downtown Durham

Dan H.

A white door with a glass panel, a keyhole, and a view of a kitchen with cabinets and a countertop.

19. New & Renovated MCM Main Level Duplex 3 mi to Duke Hospital

Durham

A two-story house with a front porch, a small front yard, and a tree with white blossoms.

20. The secret Manor

Durham

James W.

View all properties

Learn more about Durham

Stroll through Duke University's Gothic campus before catching a Durham Bulls baseball game at their downtown stadium. Dive into the city's food scene at the renovated American Tobacco Campus, where former warehouses now house top-notch restaurants and breweries.

See all hotels in Durham

A water feature with a metal structure overhead, a brick building, and a pathway with railings.

Top reviews in Durham

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

Washington Duke Inn & Golf Club

Durham

10/10 Excellent

Heather

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

Hampton Inn & Suites Durham University Medical Center

Durham

10/10 Excellent

Susan

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

Fairfield by Marriott Inn & Suites Durham

Durham

10/10 Excellent

ROXANA L

A fire pit with seating, a dining area with tables and chairs, and a building with a brick facade.

Home2 Suites by Hilton Durham University Medical Center

Durham

10/10 Excellent

We love staying at Home2 Suites. The rooms are clean and spacious; my (adult) child has a significant food allergy, so the convenience of washable dishes (and dishwasher), full-sized refrigerator, and microwave are well worth paying a little extra. The gym and indoor pool are also nice features (that we did not partake of, haha!) We also really like the hot chocolate bar and the afternoon cookies! This Home2 Suites is paired with a Hampton Inn so it has a standard Hampton Inn free...

Amanda