Find Luxury Hotels in Little Italy, CA

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Our top choices for Little Italy luxury hotels

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Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (95)
"It was a nice place to stay at"
United States
Eric
The price is AED 404
AED 468 total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott San Diego Downtown Little Italy
Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is AED 432
AED 662 total
includes taxes & fees
15 Dec - 16 Dec
San Diego Mission Bay Resort
Water view
Kona Kai San Diego

Kona Kai San Diego

Kona Kai San Diego
4.0 star property
Point Loma
8.2 out of 10, Very Good, (1000)
"had a wonderful time for our honey moon here "
United States
Anna
The price is AED 553
AED 856 total
includes taxes & fees
10 Jan - 11 January 2026
Kona Kai San Diego
Lobby
Hotel La Jolla, Curio Collection by Hilton

Hotel La Jolla, Curio Collection by Hilton

Hotel La Jolla, Curio Collection by Hilton
4.0 star property
La Jolla Shores
8.4 out of 10, Very Good, (468)
"Loved the decor, the staff, size of rooms and the Sea and Sky restaurant is ourstanding."
United States
Becky
The price is AED 585
AED 796 total
includes taxes & fees
6 Jan - 7 January 2026
Hotel La Jolla, Curio Collection by Hilton
Exterior
Hilton San Diego/Del Mar

Hilton San Diego/Del Mar

Hilton San Diego/Del Mar
4.0 star property
Del Mar Heights
8.4 out of 10, Very Good, (1003)
"It was ok. Nothing to write home about. Good hotel, good rooms. AC was noisy."
United States
Ronald
The price is AED 428
AED 487 total
includes taxes & fees
22 Dec - 23 Dec
Hilton San Diego/Del Mar
Exterior
Loews Coronado Bay Resort

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
Silver Strand
8.8 out of 10, Excellent, (1067)
"My stay was wonderful! "
United States
Jeanine
The price is AED 657
AED 908 total
includes taxes & fees
16 Dec - 17 Dec
Loews Coronado Bay Resort
Meeting facility
Pier South Resort, Autograph Collection by Marriott

Pier South Resort, Autograph Collection by Marriott

Pier South Resort, Autograph Collection by Marriott
4.0 star property
Imperial Beach
8.4 out of 10, Very Good, (1001)
"Staff was amazing room with the view was just stunning "
United States
Alisa
The price is AED 578
AED 742 total
includes taxes & fees
19 Dec - 20 Dec
Pier South Resort, Autograph Collection by Marriott
Lobby
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1163)
"Amenities and location were great. "
United States
Julie
The price is AED 559
AED 797 total
includes taxes & fees
15 Dec - 16 Dec
Margaritaville Hotel San Diego Gaslamp Quarter
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1062)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is AED 497
AED 682 total
includes taxes & fees
20 Dec - 21 Dec
The Westin San Diego Bayview
3 outdoor pools, cabanas (surcharge), pool umbrellas
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1572)
"Loved our stay "
United States
Jeremy
The price is AED 474
AED 739 total
includes taxes & fees
18 Dec - 19 Dec
Hyatt Regency Mission Bay Spa and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Little Italy Hotel Reviews

Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"Close to the airport. Very nice hotel. Easy uber to the city."
Zoran 2-night trip
Posted 1 day ago
Sheraton San Diego Resort

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Frequently asked questions

Are you looking for a luxury hotel for your stay in Little Italy?
Expedia can help you get a flight to San Diego Intl. Airport (SAN) airport or San Diego, CA (MYF-Montgomery Field) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a vacation, so we make it easy to find what you want to make your stay special. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Little Italy offers. During your visit, you might want to enjoy the restaurants and cafes which Little Italy is known for.
What's there to see and do in Little Italy?
Experience Little Italy with a stop at Maritime Museum of San Diego, San Diego Bay, and Star of India. If you have a bit of extra time while you're in the area, you might want to check out San Diego Zoo and Port of San Diego.
How can I get around Little Italy?
It's easier to get around town in style when you know your options. Make your way to County Center - Little Italy Station to catch metro.