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Top Panama City Luxury Hotels

Sofitel Legend Casco Viejo, Panama City

5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (553)
"Great hotel and location "
United Kingdom
Russell
The price is AED 1,504
AED 1,654 total
includes taxes & fees
15 Dec - 16 Dec
Sofitel Legend Casco Viejo, Panama City

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is AED 1,146
AED 1,260 total
includes taxes & fees
9 Dec - 10 Dec
Hotel La Compañía Casco Antiguo

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1005)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is AED 922
AED 1,014 total
includes taxes & fees
4 Jan - 5 January 2026
JW Marriott Panama

Dreams Playa Bonita Panama - All Inclusive

4.0 star property
Veracruz
7.6 out of 10, Good, (1006)
"This one of the best vacation I ever had."
United States
CASSANDRA
The price is AED 999
AED 999 total
includes taxes & fees
18 Dec - 19 Dec
Dreams Playa Bonita Panama - All Inclusive

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1002)
"Great staff, perfect location, and delicious breakfast. "
United States
Tatiana
The price is AED 742
AED 816 total
includes taxes & fees
12 Dec - 13 Dec
Central Hotel Panama Casco Viejo

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (636)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is AED 851
AED 936 total
includes taxes & fees
12 Dec - 13 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

American Trade Hotel

4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (600)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is AED 1,071
AED 1,178 total
includes taxes & fees
4 Jan - 5 January 2026
American Trade Hotel

W Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1003)
"Clean room, great views, great staff!"
United States
Ashley
The price is AED 761
AED 837 total
includes taxes & fees
16 Dec - 17 Dec
W Panama

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very Good, (1003)
"Clean rooms , friendly staff , had great experience "
United States
Saro
The price is AED 643
AED 708 total
includes taxes & fees
16 Dec - 17 Dec
The Westin Playa Bonita Panama

Hilton Panama

5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1001)
"Great place to stay."
United States
Salvador
The price is AED 684
AED 752 total
includes taxes & fees
2 Jan - 3 January 2026
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Panama City

Panama Cityand its attractions for luxury travelers

Panama City, the vibrant capital of Panama, offers an enticing mix of modern luxury and rich cultural heritage, perfect for travelers. Start your journey at the iconic Biomuseo, designed by Frank Gehry, where you can marvel at the unique architecture while learning about the biodiversity of Panama. Next, indulge in the upscale shopping experience at the Multiplaza Pacific Mall, featuring designer boutiques and gourmet dining options. For a dose of history, stroll through Casco Viejo, a UNESCO World Heritage site, where cobblestone streets are lined with beautifully restored historic buildings and chic cafes. Don't miss a sunset cruise on the Panama Canal; the views of the ships navigating this engineering marvel are simply breathtaking. Finally, the Amador Causeway offers stunning views of the city skyline and is perfect for a leisurely bike ride or a romantic dinner at one of the waterfront restaurants. For a luxurious stay, the Punta Pacifica area is particularly appealing, high-end hotels with ocean views, top amenities, and easy access to these attractions, ensuring you feel pampered throughout your visit.

Find the best luxury hotels and resorts in Panama City

For travelers seeking a luxurious stay in Panama City, these top hotels offer an exceptional blend of comfort, style, and exclusive amenities. Each hotel promises an indulgent experience that caters to discerning tastes.

Sofitel Legend Casco Viejo, Panama City

  • Why it's great for a luxury retreat: Sofitel Legend Casco Viejo is the epitome of luxury, with a stunning review rating of 9.8. This elegant hotel offers a swim-up bar and an exquisite restaurant with garden views, making it a perfect retreat for travelers. Located in the historic Casco Viejo neighborhood, it combines modern luxury with rich local heritage.
  • Other amenities: The hotel features an outdoor pool, a full-service spa offering various treatments, and fitness facilities open 24 hours. Guests can indulge in 24-hour room service and enjoy the convenience of valet parking. Additional amenities include airport transportation, a concierge service, and stunning views from select rooms, ensuring an unforgettable stay for all guests.
  • Neighborhood: Casco Viejo
  • Nearby attractions: Avenida Balboa - 0.89 miles, Metropolitan Cathedral of Panama - 0.26 miles, National Theater - 0.15 miles

Ramada Plaza By Wyndham Panama Punta Pacífica

  • Why it's great for a luxury retreat: With a remarkable review rating of 9.4, Ramada Plaza offers luxury travelers stylish accommodations and attentive service. This hotel stands out with its premium bedding and couples dining options, ensuring a romantic and comfortable retreat. Located in the upscale San Francisco neighborhood, it provides easy access to high-end shopping and dining experiences.
  • Other amenities: Guests can indulge in a variety of amenities, including an inviting outdoor pool, a free buffet breakfast daily, and a fully equipped fitness center open 24 hours. The hotel also features a shopping mall on-site and concierge services to assist with travel arrangements. For those seeking relaxation, a spa with treatment rooms and a romantic ambiance make it an ideal getaway for couples.
  • Neighborhood: San Francisco
  • Nearby attractions: Calle 50 - 0.41 miles, Multiplaza Pacific Mall - 0.21 miles, ATLAPA Conventions Center - 0.64 miles

Bristol Panama, a Registry Collection Hotel

  • Why it's great for a luxury retreat: Bristol Panama is a luxurious choice for travelers, an impressive review rating of 9.4. This hotel combines elegance with comfort, featuring premium bedding and a 24-hour room service option. Located in Bella Vista, it offers access to an art gallery on-site, making it perfect for art enthusiasts looking to explore the local culture.
  • Other amenities: The hotel also features a 24-hour outdoor pool, a full-service spa, and a well-appointed fitness center. Guests can enjoy designer toiletries, bathrobes, and deep-soaking bathtubs in their rooms, enhancing their luxurious experience. Additional perks include valet parking, a terrace for relaxation, and convenient airport shuttle services, ensuring a straightforward stay for all visitors.
  • Neighborhood: Bella Vista
  • Nearby attractions: Avenida Balboa - 0.44 miles, Calle 50 - 0.43 miles, Uruguay Street - 0.34 miles

Marriott Panama Hotel

  • Why it's great for a luxury retreat: Marriott Panama Hotel is a luxurious destination rated 9.2, perfect for those seeking elegance and comfort. The hotel offers an exquisite experience with premium bedding and a full-service concierge, ensuring that guests receive personalized attention throughout their stay. Located near a shopping mall, it provides easy access to upscale retail and dining options.
  • Other amenities: Guests can unwind at the outdoor pool or enjoy a cocktail at the poolside bar. The hotel features a 24-hour fitness center, valet parking, and climate control in rooms for added comfort. Additional offerings include complimentary buffet breakfast, deep soaking bathtubs, and a kitchen in select suites, catering to the needs of luxury travelers looking for convenience and indulgence.
  • Nearby attractions: Albrook Shopping Mall - 0.0 miles, Panama Canal Railway - 1.84 miles

Hotel Riu Plaza Panama

  • Why it's great for a luxury retreat: Hotel Riu Plaza Panama is an exceptional choice for luxury travelers, offering a stunning review rating of 9.0. Guests can enjoy a host of luxury amenities including a chic poolside bar and exclusive club lounge access, making for a truly refined experience. The hotel's prime location in Bella Vista places travelers near upscale shopping and dining options, ensuring convenience and elegance during their stay.
  • Other amenities: In addition to its luxurious offerings, the hotel features a relaxing outdoor pool, a full-service spa, and a well-equipped fitness center for those looking to maintain their wellness routine. Guests will appreciate the complimentary buffet breakfast, daily housekeeping, and 24-hour concierge service, ensuring every need is met. For added convenience, the hotel offers valet parking and a shopping district right on-site, enhancing the overall experience for travelers.
  • Neighborhood: Bella Vista
  • Nearby attractions: Calle 50 - 0.0 miles, Uruguay Street - 0.91 miles, Via Espana - 0.61 miles

Top Panama City Hotel Reviews

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Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Megapolis Hotel Panamá and W Panama are other upscale choices for your trip.
How many luxury hotels will I be able to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to venture outside of the area, hop on a train at Panama City Passenger Station.