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Find Casinos in Sikeston, MO

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Pick from 9 Sikeston Casinos and compare room rates, reviews, and availability. Most hotels are fully refundable.

Town House Inn Cape Giradreau
Exterior
Town House Inn Cape Giradreau
2.5 star property
6.0 out of 10, (142)
"Nothing like the one in jackson. I stayed at the townhouse inn in jackson mo then the one in cape girardeau. The one in jackson 10 stars the one in cape 2 stars so its woryh the 5 min drive "
The price is AED 239
AED 279 total
includes taxes & fees
20 Jun - 21 Jun
Town House Inn Cape Giradreau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, (1000)
"Very nice and clean with great location and excellent staff. "
The price is AED 430
AED 477 total
includes taxes & fees
27 Jun - 28 Jun
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1002)
"Fairly quiet, clean property real nice staff very helpful"
The price is AED 195
AED 220 total
includes taxes & fees
23 Jun - 24 Jun
Pear Tree Inn Cape Girardeau Near the Medical Center
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (636)
"Daughter had grandbaby #4 ... I always like to stay here. Staff is amazing. This location is super easy to get to right off highway to shopping and restaurants. Super quiet. "
The price is AED 292
AED 345 total
includes taxes & fees
23 Jun - 24 Jun
Candlewood Suites Cape Girardeau, an IHG Hotel
Auburn Place Hotel And Suites
Indoor pool
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1002)
"When we first checked in, Karen at the front desk was AWESOME! There were cookies and milk and she directed us about the amenities of the hotel as well as the best place to park based on our room location. The room itself, while small and had some dated fixtures/doors, was very clean. I was thoroughly impressed! We went to the pool area that seemed busy and they were out of towels but that was okay. We used the dollar-to-coin change machine and played a few games of pool in the game area,...
The price is AED 241
AED 271 total
includes taxes & fees
24 Jun - 25 Jun
Auburn Place Hotel And Suites
Pear Tree Inn Cape Girardeau West
Exterior
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1000)
"We have stayed here several times visiting our son at SEMO. Clean and friendly staff. Close to shopping and restaurants."
The price is AED 225
AED 254 total
includes taxes & fees
24 Jun - 25 Jun
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Exterior
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (789)
"The hotel is located in an area with shopping and restaurants are in walking distance. It is very clean and quiet. "
Drury Inn & Suites Cape Girardeau
Quality Inn
Exterior
Quality Inn
2.5 star property
7.0 out of 10, Good, (474)
"Remote to TV didn't work. Replaced batteries, still didn't work. Had to unplug TV to turn it off."
The price is AED 250
AED 282 total
includes taxes & fees
27 Jun - 28 Jun
Quality Inn
Comfort Suites Jackson-Cape Girardeau
Exterior
Comfort Suites Jackson-Cape Girardeau
2.5 star property
8.2 out of 10, Very Good, (644)
"Clean comfortable room"
The price is AED 342
AED 366 total
includes taxes & fees
20 Jun - 21 Jun
Comfort Suites Jackson-Cape Girardeau
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Searching for casino hotels in Sikeston?
Tourists speak highly of the family-friendly activities, shopping, and local cuisine.
How many hotels that are good for gaming can I expect to find in Sikeston?
You won’t need a stroke of luck to find something that suits with one of Expedia’s 13 casino hotels in Sikeston.
When should I take my casino trip to Sikeston?
You might spend a lot of your vacation inside, but if you want to see more of the area, looking at local weather trends is a good idea. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What is there to do in Sikeston?
If you’re interested in local cultural spots, you can check out Sikeston Depot Museum and Front Street Studio & Art Gallery. Nature enthusiasts will appreciate the riverfront, and places to get outdoors include Mississippi River. If you’re looking for more to see and do, you can add The Book Bug and Central Park to your list.
What are my transportation options for my casino getaway to Sikeston?
Here are some transportation options in Sikeston: You can arrange a flight to the nearest airport, which is Cairo, IL (CIR-Cairo Regional), 23.8 mi (38.3 km) from the city center. If you’d like to explore around the area, you may want a rental car for your journey.

Recent reviews of Sikeston hotels
Expedia verified reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

5/5 Excellent
"Very nice and clean with great location and excellent staff. "
A verified traveler stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Posted 2 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel