Photo by Ryan Coleman

Find Casinos in Sikeston, MO

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Sikeston Casinos

Tonight
1 Oct - 2 Oct
Tomorrow
2 Oct - 3 Oct
This weekend
3 Oct - 5 Oct
Next weekend
10 Oct - 12 Oct

Top Sikeston Casinos

Town House Inn Cape Giradreau
Desk, free WiFi

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (197)
"Staff could have used more training. But overall it was a good experience "
The price is AED 220
AED 257 total
includes taxes & fees
2 Oct - 3 Oct
Town House Inn Cape Giradreau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"It was right off the interstate with lots of restaurant options "
The price is AED 349
AED 394 total
includes taxes & fees
19 Oct - 20 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1012)
"Staff was friendly, room was clean, good location, good rate."
The price is AED 257
AED 290 total
includes taxes & fees
6 Oct - 7 Oct
Pear Tree Inn Cape Girardeau Near the Medical Center
Candlewood Suites Cape Girardeau by IHG
Exterior

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.0 out of 10, Very Good, (852)
"Great staff and convenient location "
The price is AED 286
AED 343 total
includes taxes & fees
12 Oct - 13 Oct
Candlewood Suites Cape Girardeau by IHG
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there."
The price is AED 257
AED 290 total
includes taxes & fees
2 Oct - 3 Oct
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Excellent place. Really friendly staff"
The price is AED 331
AED 373 total
includes taxes & fees
7 Oct - 8 Oct
Drury Inn & Suites Cape Girardeau
Quality Inn
Lobby

Quality Inn

2.5 star property
7.2 out of 10, Good, (644)
"nice stay"
The price is AED 212
AED 239 total
includes taxes & fees
7 Oct - 8 Oct
Quality Inn
Comfort Suites Jackson-Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (734)
"Great area, fast check in, quiet, very spacious"
The price is AED 327
AED 354 total
includes taxes & fees
5 Oct - 6 Oct
Comfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sikeston Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"Very convenient and felt safe"
Pamela 1-night trip
Posted 1 day ago
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Everything was clean and looked newly renovated. Staff was friendly. Parking was convenient and the area seemed safe. "
Lisa 2-night trip
Posted 5 days ago
Pear Tree Inn Cape Girardeau West

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Searching for casino hotels in Sikeston?
Tourists speak highly of the family-friendly activities, shopping, and local cuisine.
How many hotels that are good for gaming can I expect to find in Sikeston?
You won't need a stroke of luck to find something that suits with one of Expedia's 15 casino hotels in Sikeston.
When should I take my casino trip to Sikeston?
You might spend a lot of your vacation inside, but if you want to see more of the area, looking at local weather trends is a good idea. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What is there to do in Sikeston?
If you're interested in local cultural spots, you can check out Sikeston Depot Museum and Front Street Studio & Art Gallery. Nature enthusiasts will appreciate the riverfront, and places to get outdoors include Big Oak Tree State Park, Shawnee National Forest, and Mississippi River. If you're looking for more to see and do, you can add Central Park and Stoddard County Civil War Memorial Cemetery to your list.
What are my transportation options for my casino getaway to Sikeston?
Here are some transportation options in Sikeston: You can arrange a flight to the nearest airport, which is Cairo, IL (CIR-Cairo Regional), 23.8 mi (38.3 km) from the city center. If you'd like to explore around the area, you may want a rental car for your journey.