Photo by Ryan Coleman
Find 2 Star Hotels in Sikeston, MO from AED 219
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Sikeston 2 Star Hotels
Compare Sikeston 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Riverview
The Riverview
9.4 out of 10, Exceptional, (299)
The price is AED 387
AED 436 total
includes taxes & fees
22 Jun - 23 Jun

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1001)
The price is AED 364
AED 410 total
includes taxes & fees
29 Jun - 30 Jun

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1003)
The price is AED 324
AED 369 total
includes taxes & fees
22 Jun - 23 Jun

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1002)
The price is AED 281
AED 320 total
includes taxes & fees
22 Jun - 23 Jun

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
8.0 out of 10, Very Good, (801)
The price is AED 301
AED 360 total
includes taxes & fees
30 Jun - 1 Jul

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1006)
The price is AED 264
AED 298 total
includes taxes & fees
23 Jun - 24 Jun

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
9.0 out of 10, Wonderful, (1006)
The price is AED 239
AED 269 total
includes taxes & fees
17 Jun - 18 Jun

Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHG
9.4 out of 10, Exceptional, (474)
The price is AED 378
AED 433 total
includes taxes & fees
29 Jun - 30 Jun
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Sikeston.

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
The price is AED 330 per night from Jun 23 to Jun 24
AED 330
AED 373 total
23 Jun - 24 Jun
includes taxes & fees
9.4/10 Exceptional! (1,004 reviews)
Still don't see what you're looking for?
See all properties in Sikeston.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston and related destinations
Explore Sikeston: its food, riverfront, university life, and more!

Photo by Ryan Coleman
Open Photo by Ryan Coleman
Recent reviews of Sikeston hotels
Recent reviews of Sikeston hotels

The Riverview
5/5 Excellent
"Great property. I wasn’t there long, but it was clean and comfortable. "
A verified traveler stayed at The Riverview
Posted 13 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Sikeston Hotels by Star Rating
Stay near popular Sikeston attractions
- Hotels near The Book Bug
- Hotels near Sikeston Depot Museum
- Hotels near Central Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
- Hotels near eDen Spa & Salon
- Hotels near The Heritage House
- Hotels near Fort Defiance State Park
- Hotels near New Madrid Historical Museum
- Hotels near Big Oak Tree State Park
- Hotels near Dexter Welcome Center Depot and Museum
- Hotels near River Ridge Winery
- Hotels near Stoddard County Civil War Memorial Cemetery
- Hotels near Marston Community Center
- Hotels near Mound City National Cemetery
- Hotels near Fort D Historic Site
More Hotel Options in Sikeston
- Adults Only Resorts & Hotels in Sikeston
- Adventure Hotels in Sikeston
- Business Hotels in Sikeston
- Casinos in Sikeston
- Cheap Hotels in Sikeston
- Family Hotels in Sikeston
- Golf Hotels in Sikeston
- Historic Hotels in Sikeston
- Hotel Wedding Venues in Sikeston
- Hotels with Bars in Sikeston
- Hotels with Free Parking in Sikeston
- Hotels with Hot Tubs in Sikeston
- Hotels with WiFi in Sikeston
- Hotels with a Pool in Sikeston
- Hotels with an Indoor Pool in Sikeston
- Hotels with smoking rooms in Sikeston
- Luxury Hotels in Sikeston
- Pet-friendly Hotels in Sikeston
- Resorts & Hotels with Spas in Sikeston
- Romantic Hotels in Sikeston
- Shopping Hotels in Sikeston
- Winery Hotels in Sikeston
Explore more hotels
- Drury Plaza Hotel Cape Girardeau Conference Center
- The Riverview
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Candlewood Suites Cape Girardeau by IHG
- Pear Tree Inn Cape Girardeau West
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Courtyard by Marriott Cape Girardeau Downtown
- Holiday Inn Express & Suites Perryville by IHG
- Drury Inn & Suites Jackson MO
- Quality Inn
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Tru By Hilton Cape Girardeau
- Drury Inn & Suites Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Hotel 7 Inn Anna
- Beautiful location in the secluded woods
- Super 8 by Wyndham Perryville
- Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
- Hampton Inn Cape Girardeau I 55 East