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Find Luxury Hotels in Sikeston, MO

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Check availability on Sikeston Luxury Hotels

Top Sikeston Luxury Hotels

Days Inn and Suites by Wyndham Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"We were there to get a good nights sleep and we did."
The price is AED 281
AED 320 total
includes taxes & fees
22 Jun - 23 Jun
Days Inn and Suites by Wyndham Sikeston
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Property grounds

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

10.0 out of 10, Exceptional, (216)
"Loved the view of the mighty Mississippi!"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Pear Tree Inn Cape Girardeau Near the Medical Center
Seasonal outdoor pool

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1005)
"In proximity to shopping and restaurants. Would stay again"
The price is AED 239
AED 269 total
includes taxes & fees
17 Jun - 18 Jun
Pear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn
Lobby

Quality Inn

2.5 star property
7.0 out of 10, Good, (593)
"Great room, great experience "
The price is AED 235
AED 265 total
includes taxes & fees
17 Jun - 18 Jun
Quality Inn
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Best hotel ever loved it"
The price is AED 349
AED 401 total
includes taxes & fees
29 Jun - 30 Jun
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (942)
"Room was very clean and staff was excellent!"
The price is AED 347
AED 391 total
includes taxes & fees
22 Jun - 23 Jun
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you looking for a luxury hotel for your stay in Sikeston?
Use Expedia and let us help you arrange a flight to Cairo, IL (CIR-Cairo Regional) airport or Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Sikeston has to offer. During your visit, you might want to enjoy the shopping which Sikeston is known for.
How many luxury hotels will I find in Sikeston?
Lie in the lap of luxury during your getaway to Sikeston in one of Expedia’s 5 luxury hotels.
When can I expect good weather in Sikeston?
Planning for the weather is a good way to make your trip to Sikeston relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do in Sikeston?
Experience Sikeston with a stop at Sikeston Depot Museum, The Book Bug, and Central Park. If you have a little extra time during your trip, you might want to make a stop at Boot Heel Golf Club and Front Street Studio & Art Gallery.