Photo by Ryan Coleman

Find 4 Star Hotels in Sikeston, MO

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Sikeston 4 Star Hotels

Tonight
6 Aug - 7 Aug
Tomorrow
7 Aug - 8 Aug
This weekend
8 Aug - 10 Aug
Next weekend
15 Aug - 17 Aug

Compare Sikeston 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Davie School Inn
Gold Suite | View from room

Davie School Inn

4.0 star property
10.0 out of 10, Exceptional, (51)
"One of the coolest and unique places we’ve stayed. It’s clean, quiet and the decor is perfect for this converted school. It felt like a slumber party in a classroom! "
Davie School Inn
Urban Lofts
Street view

Urban Lofts

4.0 star property
Urban Lofts
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Sikeston?
Expedia can help you quickly find the perfect 4-star hotel for your getaway in Sikeston. Use our handy filter tool to tailor your search by things like budget, conveniences and property star rating and get access to awesome deals in a couple of clicks.

  • Search for the lowest price

What's the difference between 5-star and 4-star hotels in Sikeston?
If you decide to spend your vacation at a 4-star hotel in Sikeston, you'll usually find loads of amenities to ensure you're comfortable, such as a gym, pool and restaurant. You can enjoy top-quality service and upscale surroundings. Pick a 5-star hotel and you'll get a few more perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You're likely to get more amenities and first-class services at a 5-star getaway, but both are fabulous options for luxury travelers.
Does Sikeston have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Sikeston where everything is taken care of, from your meals to your room, entertainment and activities. We can also help you find standard 4-star stays in and around this destination.