Find Luxury Hotels in Downtown Santiago

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Check availability on Downtown Santiago Luxury Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Downtown Santiago Luxury Hotels

Terrace/patio
The Singular Santiago

The Singular Santiago

5.0 star property
Downtown Santiago
9.6 out of 10, Exceptional, (672)
"The staff were wonderful and did a great job."
United States
Muthukumarappan
The price is AED 863
AED 863 total
24 Dec - 25 Dec
The Singular Santiago
Interior detail
Casa Bueras Boutique Hotel

Casa Bueras Boutique Hotel

4.5 star property
Downtown Santiago
9.2 out of 10, Wonderful, (510)
"The staff were all so incredibly nice!!! The hotel was beautiful too!!"
United States
Kimberly
The price is AED 507
AED 507 total
22 Dec - 23 Dec
Casa Bueras Boutique Hotel
Deluxe Double Room | Premium bedding, in-room safe, individually decorated
Luciano K Hotel

Luciano K Hotel

4.5 star property
Downtown Santiago
9.0 out of 10, Wonderful, (681)
"Staff is amazing. Building is beautiful and so well preserved. Excellent stay."
United States
Joao Carlos
The price is AED 500
AED 500 total
3 Jan - 4 January 2026
Luciano K Hotel
Lobby
Altiplanico Bellas Artes

Altiplanico Bellas Artes

3.5 star property
Downtown Santiago
9.2 out of 10, Wonderful, (553)
"Great location for the centre and nearby dining establishment's "
United Kingdom
Kathleen
Altiplanico Bellas Artes
Terrace/patio
Matildas Hotel Boutique

Matildas Hotel Boutique

3.5 star property
Downtown Santiago
9.4 out of 10, Exceptional, (276)
"Wonderful, memorably experience in the beautiful boutique hotel! Highly recommend. "
Canada
Emily
The price is AED 483
AED 483 total
12 Dec - 13 Dec
Matildas Hotel Boutique
Bar (on property)
Hotel Plaza San Francisco

Hotel Plaza San Francisco

4.0 star property
Downtown Santiago
9.2 out of 10, Wonderful, (961)
"Clean room and good service."
United States
Fernando
The price is AED 577
AED 577 total
8 Dec - 9 Dec
Hotel Plaza San Francisco
Superior Duplex | Terrace/patio
Lastarria Hotel & Aparts

Lastarria Hotel & Aparts

3.0 star property
Downtown Santiago
9.2 out of 10, Wonderful, (266)
"Wonderful place. Very kind people, clean rooms. "
United States
Mohsen
The price is AED 429
AED 429 total
21 Dec - 22 Dec
Lastarria Hotel & Aparts
Property entrance
Hotel Vegas

Hotel Vegas

3.0 star property
Downtown Santiago
8.0 out of 10, Very Good, (187)
"This was a wonderful little boutique hotel on a walkable cobbled street. The staff was exceptional and the room was very comfortable and quiet. It was easily in walking distance to Centro and right by a subway stop. Wonderful little place to stay. Thank you!"
United States
Tamara
Hotel Vegas
Standard Apartment, 1 Bedroom | Iron/ironing board, free WiFi, bed sheets
Rukaza Lastarria

Rukaza Lastarria

3.0 star property
Downtown Santiago
8.6 out of 10, Excellent, (46)
"Pros - Great location - safe area, close to bars and restaurants, easy to catch the train. The not so pros (cons) - hotel room smaller then photos, Spanish service desk only"
Australia
Anonymous traveler
Rukaza Lastarria
Hallway
Hotel Panamericano

Hotel Panamericano

3.0 star property
Downtown Santiago
8.4 out of 10, Very Good, (199)
"Great hotel and easily accessible to the markets. Highly recommend this location!"
Canada
Siong Ying
The price is AED 275
AED 275 total
15 Dec - 16 Dec
Hotel Panamericano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown Santiago Hotel Reviews

The Singular Santiago

The Singular Santiago

10/10 Excellent
"The staff were wonderful and did a great job."
Muthukumarappan 2-night trip
Posted 4 days ago
The Singular Santiago

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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Downtown Santiago?
During your visit, you might want to enjoy the museums and cathedral which Downtown Santiago is known for.
What's the best luxury accommodation in Downtown Santiago?
Luciano K Hotel is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. The Singular Santiago and Casa Bueras Boutique Hotel are other upscale choices for your stay.
What's there to see and do in Downtown Santiago?
Experience Downtown Santiago with a stop at Fantasilandia, Palacio de la Moneda, and Movistar Arena. If you have a little extra time during your trip, you might want to check out Barrio París-Londres and Municipal Theatre of Santiago.
How can I get around Downtown Santiago?
It's easier to get around town comfortably when you know your options. You can take advantage of metro transit at Toesca Station, O'Higgins Park Station, and Heroes Station.