Find Business Hotels in Downtown Santiago

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Check availability on Downtown Santiago Business Hotels

Our top choices for Downtown Santiago business-friendly hotels

Lobby
Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4.0 star property
Downtown Santiago
8.2 out of 10, Very Good, (614)
"The hotel is located at the prime spot, great place to do shopping and good restaurants around. "
United States
Sivasankar
The price is AED 294
AED 294 total
12 Dec - 13 Dec
Almacruz Hotel y Centro de Convenciones
Deluxe Double Room | Premium bedding, in-room safe, individually decorated
Luciano K Hotel

Luciano K Hotel

4.5 star property
Downtown Santiago
9.0 out of 10, Wonderful, (683)
"Friendly and helpful staff. Food at the rooftop restaurant was delicious!!"
Canada
Chantal
The price is AED 511
AED 511 total
23 Dec - 24 Dec
Luciano K Hotel
Terrace/patio
Matildas Hotel Boutique

Matildas Hotel Boutique

3.5 star property
Downtown Santiago
9.4 out of 10, Exceptional, (276)
"Wonderful, memorably experience in the beautiful boutique hotel! Highly recommend. "
Canada
Emily
The price is AED 483
AED 483 total
24 Dec - 25 Dec
Matildas Hotel Boutique
Loft, 1 Queen Bed, Kitchen | 1 bedroom, minibar, in-room safe, desk
Park Plaza Apart Hotel

Park Plaza Apart Hotel

3.0 star property
Downtown Santiago
8.4 out of 10, Very Good, (639)
"It was a very comfortable stay fir my first overnight stay in Santiago. "
Canada
Paul
The price is AED 262
AED 262 total
8 Jan - 9 January 2026
Park Plaza Apart Hotel
Bar (on property)
Hotel Plaza San Francisco

Hotel Plaza San Francisco

4.0 star property
Downtown Santiago
9.2 out of 10, Wonderful, (965)
"Location beautiful hotel lovely friendly staff Close to everything "
Canada
stan
The price is AED 577
AED 577 total
7 Jan - 8 January 2026
Hotel Plaza San Francisco
Outdoor pool, open 10:00 AM to 8:00 PM, free cabanas
Mercure Santiago Centro

Mercure Santiago Centro

3.5 star property
Downtown Santiago
8.4 out of 10, Very Good, (1000)
"Very central location. Most city landmarks at walking distance. Friendly staff."
United Kingdom
Eduardo
The price is AED 316
AED 316 total
26 Dec - 27 Dec
Mercure Santiago Centro
Reception
Hotel Fundador

Hotel Fundador

4.0 star property
Downtown Santiago
8.2 out of 10, Very Good, (365)
"Staff, cleanliness of room and breakfast could be better."
United States
Jorge
The price is AED 253
AED 253 total
2 Jan - 3 January 2026
Hotel Fundador
Exterior
Le Méridien Santiago

Le Méridien Santiago

4.0 star property
Downtown Santiago
8.4 out of 10, Very Good, (539)
"Kudos to Hotel Meridien for having Ms Ana Echeverria and Mr John Freire. They are helpful, friendly and accommodating. A pleasure to stay here. The room is immaculate, food delicious. The Hotel close to Metro yet quiet, safe area."
United States
GILBERT MENDOZA
The price is AED 312
AED 312 total
19 Dec - 20 Dec
Le Méridien Santiago
Front of property
Castelletto Bed and Breakfast

Castelletto Bed and Breakfast

3.0 star property
Downtown Santiago
9.8 out of 10, Exceptional, (6)
"Great hospitality, highly recommend everyone to come stay here 👍"
Taiwan
HungYi
The price is AED 214
AED 214 total
21 Dec - 22 Dec
Castelletto Bed and Breakfast
Outdoor pool
Hotel Ismael

Hotel Ismael

3.5 star property
Downtown Santiago
9.2 out of 10, Wonderful, (377)
"Beautiful hotel, very clean, Marcelo from the front desk has a excellent customer service and very helpful , he answered all my questions.Five stars "
United States
Guillermo
The price is AED 531
AED 531 total
18 Dec - 19 Dec
Hotel Ismael
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown Santiago Hotel Reviews

Hotel Plaza San Francisco

Hotel Plaza San Francisco

10/10 Excellent
"Clean room. Friendly and helpful staff"
Mayur 3-night trip
Posted 1 day ago
Hotel Plaza San Francisco

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