Find hotels in East Main Street, Grand Junction from AED 204

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Our top choices for East Main Street hotels

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 1.4 km from East Main Street
9.2 out of 10, Wonderful, (974)
"Spotless and modern rooms, great friendly staff. "
United States
Ruben
The price is AED 291
AED 333 total
includes taxes & fees
11 Jan - 12 January 2026
Tru by Hilton Grand Junction Downtown

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 5.4 km from East Main Street
8.8 out of 10, Excellent, (2708)
"Easy to check-in was a great quick stay"
United States
Stephanie
The price is AED 276
AED 316 total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham Grand Junction

Hotel Maverick

Hotel Maverick
4.0 star property
Capitol Hill, 1.6 km from East Main Street
9.6 out of 10, Exceptional, (1004)
"Excellent place to stay in Grand Junction. "
United States
Steve
Hotel Maverick

Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest
3.0 star property
24 Road Corridor, 5.9 km from East Main Street
9.2 out of 10, Wonderful, (873)
"Great location, clean room, very pleasant staff "
United States
Allison
The price is AED 467
AED 536 total
includes taxes & fees
17 Dec - 18 Dec
Home2 Suites by Hilton Grand Junction Northwest

Grand Vista Hotel

Grand Vista Hotel
3.5 star property
Horizon Drive District, 5.5 km from East Main Street
8.2 out of 10, Very Good, (3442)
"Good place to stay"
United States
Ramona
Grand Vista Hotel

Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG
3.0 star property
Horizon Drive District, 5.4 km from East Main Street
8.6 out of 10, Excellent, (1000)
"Room clean and comfortable, staff was awesome and attentive "
United States
Kirstin
The price is AED 327
AED 375 total
includes taxes & fees
5 Jan - 6 January 2026
Holiday Inn & Suites Grand Junction by IHG

Clarion Inn Grand Junction

Clarion Inn Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very Good, (1696)
"Very Clean, great beds, nice pool, great staff "
Canada
Deborah
The price is AED 264
AED 303 total
includes taxes & fees
21 Dec - 22 Dec
Clarion Inn Grand Junction

WoodSpring Suites Grand Junction

WoodSpring Suites Grand Junction
2.5 star property
24 Road Corridor, 5.9 km from East Main Street
6.4 out of 10, (893)
"I enjoy my stay here so much, I have decided to make it my long term resudence for a while. "
United States
Heather
The price is AED 202
AED 232 total
includes taxes & fees
14 Dec - 15 Dec
WoodSpring Suites Grand Junction

Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very Good, (1855)
"We very much enjoyed our stay there!"
United States
Kathryn
The price is AED 215
AED 247 total
includes taxes & fees
14 Dec - 15 Dec
Ramada by Wyndham Grand Junction

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
3.5 star property
Historic Grand Junction, 1.5 km from East Main Street
9.0 out of 10, Wonderful, (1001)
"Very nice family hotel with good breakfast."
United States
Margarita
The price is AED 426
AED 491 total
includes taxes & fees
21 Dec - 22 Dec
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street
2.5 star property
Historic Grand Junction, 1.5 km from East Main Street
8.8 out of 10, Excellent, (1002)
"Very clean, well managed, and a nice overall stay"
United States
Jeff
The price is AED 320
AED 367 total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Grand Junction Downtown/Historic Main Street

Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction
2.5 star property
18.5 km from East Main Street
8.4 out of 10, Very Good, (1003)
"The location was convenient and the staff was friendly. "
United States
Charles
The price is AED 250
AED 285 total
includes taxes & fees
14 Dec - 15 Dec
Comfort Inn & Suites Fruita - Grand Junction

Courtyard by Marriott Grand Junction

Courtyard by Marriott Grand Junction
3.0 star property
Horizon Drive District, 5.6 km from East Main Street
8.4 out of 10, Very Good, (1000)
"Friendly staff and clean room "
United States
Jennifer
The price is AED 342
AED 392 total
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott Grand Junction

Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
3.0 star property
Horizon Drive District, 4.9 km from East Main Street
8.6 out of 10, Excellent, (1000)
"Great staff."
United States
Manford
The price is AED 231
AED 265 total
includes taxes & fees
21 Dec - 22 Dec
Quality Inn Grand Junction near University

Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction
4.0 star property
Horizon Drive District, 5 km from East Main Street
8.0 out of 10, Very Good, (1000)
"Good value, nice big room, convenient"
United States
Kathy
The price is AED 318
AED 365 total
includes taxes & fees
8 Jan - 9 January 2026
Doubletree Hotel Grand Junction

Wine Country Inn Palisade

Wine Country Inn Palisade
3.5 star property
17.1 km from East Main Street
9.6 out of 10, Exceptional, (1001)
"We loved the location near the wineries. Great place to stay!!"
United States
Sara
Wine Country Inn Palisade

Comfort Inn Grand Junction I-70

Comfort Inn Grand Junction I-70
2.5 star property
Horizon Drive District, 5.4 km from East Main Street
8.6 out of 10, Excellent, (1004)
"Manager was wonderful at check in, breakfast was good. "
United States
Dean
The price is AED 271
AED 311 total
includes taxes & fees
14 Dec - 15 Dec
Comfort Inn Grand Junction I-70

Holiday Inn Express & Suites Grand Junction by IHG

Holiday Inn Express & Suites Grand Junction by IHG
2.5 star property
24 Road Corridor, 5.9 km from East Main Street
8.6 out of 10, Excellent, (1000)
"The room was great and the staff was very nice. "
United States
Clarissa
The price is AED 573
AED 657 total
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express & Suites Grand Junction by IHG

Super 8 by Wyndham Fruita

Super 8 by Wyndham Fruita
2.0 star property
18.5 km from East Main Street
8.4 out of 10, Very Good, (1000)
"Nice place with lots of food choices within a walkable block."
United States
Daniel
The price is AED 235
AED 269 total
includes taxes & fees
14 Dec - 15 Dec
Super 8 by Wyndham Fruita

Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
2.5 star property
8.7 km from East Main Street
8.8 out of 10, Excellent, (792)
"Room and breakfast was typucal, ut bummed the pool and hot tub were closed."
United States
Phil
The price is AED 340
AED 358 total
includes taxes & fees
17 Dec - 18 Dec
Best Western Grande River Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in East Main Street

Find the best East Main Street areas and neighborhoods for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Pear Park

If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Horizon Drive District

While there might not be top attractions in Horizon Drive District, you can explore the larger area and discover places like Grand Junction Motor Speedway and Canyon View Park.

Top East Main Street Hotel Reviews

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Frequently asked questions

What's it like in East Main Street?
Travelers will be sure to enjoy their time in Grand Junction's East Main Street neighborhood.
Where is the best hotel for a stay in East Main Street?
Based on our traveler data, Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars. is one of the top choices for your stay in East Main Street. This guesthouse offers private balconies and a fitness center. Other good choices for your stay in the area include Grand Junction Vacation Rental w/ Fire Pit! and Launch your Colorado adventures – Historic Downtown convenience.
How many hotels will I be able to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 22 East Main Street hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get top deals in East Main Street.
Where can I learn more about changing or cancelling my trip to East Main Street?
To find more details about updating your trip to East Main Street or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Grand Junction neighborhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens, and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.