Santo Spirito

Florence

Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Piazza Santo Spirito

Piazza Santo Spirito

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

You can learn about the history of Florence with a stop at Brancacci Chapel. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Brancacci Chapel
Uffizi Gallery

Uffizi Gallery

Uffizi Gallery is a top museum in Florence with a rich history. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Uffizi Gallery
Ponte Vecchio which includes a bridge and a river or creek

Ponte Vecchio

Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the stunning cathedral and notable monuments in this vibrant area.

Ponte Vecchio
Cathedral of Santa Maria del Fiore featuring a city, heritage architecture and a church or cathedral

Cathedral of Santa Maria del Fiore

Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Cathedral of Santa Maria del Fiore

Santo Spirito Hotel Deals

UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59, Florence, FI
The price is AED 423 per night from Aug 17 to Aug 18
AED 423
AED 525 total
17 Aug - 18 Aug
includes taxes & fees
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (986 reviews)
"Amazing place, love the decor!"

Reviewed on 28 July 2025

UNA Hotels Vittoria Firenze
Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13, Florence, FI
The price is AED 497 per night from Aug 20 to Aug 21
AED 497
AED 606 total
20 Aug - 21 Aug
includes taxes & fees
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (546 reviews)
"Our two night stay at Horto Convento was very nice, from the friendly, helpful staff, to the comfortable bed, to the delicious breakfast. The property is located away from a busy street, in a lovely setting next to a church. If I had to note any issue at all, it would be the very narrow bathroom ..."

Reviewed on 6 August 2025

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,011 reviews)
"Property was very well kept and very comfortable beds. It’s walking distance from most attractions."

Reviewed on 5 August 2025

Get rates
Palazzo Mannaioni Suites
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8, Florence, FI
The price is AED 407 per night from Aug 13 to Aug 14
AED 407
AED 499 total
13 Aug - 14 Aug
includes taxes & fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (193 reviews)
Perfect spot
"Amazing room, we were on the first floor and had very tall ceilings in a very cool building. Safe area and secure building as well. Highly recommend"

Reviewed on 21 July 2025

La Torre Del Cestello
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49, Florence, FI
The price is AED 337 per night from Aug 11 to Aug 12
AED 337
AED 422 total
11 Aug - 12 Aug
includes taxes & fees
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (159 reviews)
"La Foresteria es cómoda, limpia y tranquila. Tiene todo lo que necesitas para pasar varias noches en Florencia. El personal es cálido y amable. Está ubicada en un muy buen barrio, menos turístico pero con muy buenos restaurantes y tienditas cerca. Está a una corta caminata del centro."

Reviewed on 23 July 2025

Foresteria Valdese di Firenze - Casa per Ferie
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Piazza del Carmine, 21, Florence, FI
The price is AED 501 per night from Aug 11 to Aug 12
AED 501
AED 602 total
11 Aug - 12 Aug
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (317 reviews)
"We were there for 2 nights in a room for 5 people; everything was extremely clean and had a good time!"

Reviewed on 9 August 2025

Casa Santo Nome di Gesù
See all 468 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Brancacci Chapel which includes a church or cathedral and heritage architecture

San Frediano

San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.

San Frediano
Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Palazzo dei Congressi is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Historic Centre of Florence

Santo Spirito

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