A coastal fortress with a stone wall and a tiled-roof building.

Find 5 Star Hotels in Syracuse from AED 590

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Check availability on Syracuse 5 Star Hotels

Tonight
12 Oct - 13 Oct
Tomorrow
13 Oct - 14 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Syracuse 5-star hotels

A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.
A balcony with a view of the sea and a cityscape, furnished with two chairs and a small table with a vase of flowers.
A dining table with multiple plates and wine glasses, set against a backdrop of a scenic ocean view.
A grand atrium with a central column, ornate railings, and a large mural on the wall.

1. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
Mexico
ALFONSO
AED 1,074
AED 1,223 total
includes taxes & fees
8 Nov - 9 Nov
Ortea Palace Hotel, Sicily, Autograph Collection
A balcony with a view of the sea, a cactus, and potted plants.
A poolside area with lounge chairs and umbrellas, a clear pool, and a building with multiple windows in the background.
A large, classical building with multiple windows and balconies, surrounded by a calm body of water with several yachts docked.
A large, multi-story building with a symmetrical facade, arched windows, and a central entrance with a colorful awning.

2. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
United States
SEAN
AED 1,042
AED 1,187 total
includes taxes & fees
2 Nov - 3 Nov
Grand Hotel Ortigia Siracusa
A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.
A terrace with a view of the sea and a cruise ship, featuring outdoor seating and potted cacti.
A spacious dining area with round tables and blue chairs, large windows offering a city view, and a wooden ceiling structure.
A grand hallway with ornate columns, a tiled floor, and large potted plants.

3. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
Canada
Steven
AED 2,317
AED 2,590 total
includes taxes & fees
21 Oct - 22 Oct
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
A multi-story building with a rooftop terrace, balconies, and a street view.
A modern hotel room with a stone accent wall, a grey sofa, a large mirror, a chandelier, and a neatly made bed with rolled towels.
A multi-story building with a rooftop terrace featuring outdoor seating and a hot tub.

4. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
Canada
Dena
AED 499
AED 590 total
includes taxes & fees
12 Nov - 13 Nov
Caportigia Boutique Hotel
A spa room with a large window, a hot tub, and two candles.
A stone building with arched walkways and outdoor seating areas.
A spacious lobby with arched ceilings, a central round table with decorative items, and a modern chandelier.
A courtyard with a stone pathway, palm trees, and potted plants.

5. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
United Kingdom
Chris
AED 1,109
AED 1,262 total
includes taxes & fees
26 Oct - 27 Oct
Dimora Caiammari Luxury Hotel & Spa
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.
A modern bathroom with a freestanding bathtub, a round table with a magazine, and a view of a pool and greenery.
A table set with breakfast items overlooking a coastal view.
A pathway lined with palm trees leading to a building with a red-tiled roof.

6. Minareto

Minareto
Syracuse
United States
Luis Alberto
AED 988
AED 1,128 total
includes taxes & fees
7 Nov - 8 Nov
Minareto
A large swimming pool with a modern building in the background.
An outdoor dining area with tables and chairs, a pool, and palm trees in the background.
A woman relaxing in a spa bath with a modern design, including a ceiling with blue lighting and a tiled floor.
A sauna with wooden benches and a central stone pillar.

7. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
Australia
Nicholas
AED 1,208
AED 1,370 total
includes taxes & fees
7 Nov - 8 Nov
Wellness & Spa Hotel Principe di Fitalia
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR
AED 707
AED 819 total
6 Nov - 7 Nov
includes taxes & fees
Algila' Ortigia Charme Hotel
UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA

Via Diodoro Siculo 4 Syracuse SR
AED 572
AED 652 total
25 Oct - 26 Oct
includes taxes & fees
8.6/10 Excellent! (555 reviews)
UNA Hotels One Siracusa Wellness & SPA
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

Via Roma 66 Syracuse SR
AED 790
AED 911 total
5 Nov - 6 Nov
includes taxes & fees
9.4/10 Exceptional! (694 reviews)
Palazzo Artemide - VRetreats, SLH Collection
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse
An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"A splendid, classic property with first rate service, comfortable beds and a glorious breakfast on a breathtaking outdoor terrace. Wish we could have stayed longer."
Richard 1-night trip
Posted 1 hour ago
Grand Hotel Ortigia Siracusa

Frequently asked questions

What are the best 5-star hotels in Syracuse?
Prepare for 5-star opulence at Grand Hotel Ortigia Siracusa, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Des Ètrangers. These are some of the best stays in Syracuse based on Expedia customer reviews. Book one and get a taste of the finer life!
How much does it cost to stay in a 5-star hotel in Syracuse?
How much you pay for a 5-star hotel in Syracuse depends on factors like when you plan to go and the length of your vacation. Our insider tip for bagging the best deal? Use our pricing filters to compare all of the available hotels for your preferred dates.
  • Search for the lowest price per night from AED 652
What makes a hotel 5 stars in Syracuse?
From high-end restaurants and fitness centers to swimming pools and superior bedding, the 5-star experience in Syracuse is all about luxury and relaxation. But it calls for more than just upscale amenities to get a 5-star rating. Hotels also have to deliver outstanding guest services like massage treatments, laundry and dry cleaning and 24-hour room service.

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