A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse 5 Star Hotels

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Syracuse 5-star hotels

A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.
A dining table with multiple plates and wine glasses, set against a backdrop of a scenic ocean view.
A grand atrium with a central column, ornate railings, and a large mural on the wall.
A balcony with a view of the sea and a cityscape, furnished with two chairs and a small table with a vase of flowers.

1. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
Mexico
ALFONSO
AED 1,286
AED 1,456 total
includes taxes & fees
1 Nov - 2 Nov
Ortea Palace Hotel, Sicily, Autograph Collection
A balcony with a view of the sea, a cactus, and potted plants.
A dining area with a table set for two, overlooking a coastal view.
A poolside area with lounge chairs and umbrellas, a clear pool, and a building with multiple windows in the background.
A large, multi-story building with a symmetrical facade, arched windows, and a central entrance with a colorful awning.

2. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
United States
SEAN
AED 1,210
AED 1,372 total
includes taxes & fees
7 Oct - 8 Oct
Grand Hotel Ortigia Siracusa
A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.
A grand hallway with a marble floor, ornate columns, and a staircase leading to an upper level.
A grand hallway with ornate columns, a tiled floor, and large potted plants.
A terrace with a view of the sea and a cruise ship, featuring outdoor seating and potted cacti.

3. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
Canada
Steven
AED 2,398
AED 2,679 total
includes taxes & fees
11 Oct - 12 Oct
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
A modern hotel room with a stone accent wall, a grey sofa, a large mirror, a chandelier, and a neatly made bed with rolled towels.
A multi-story building with a rooftop terrace, balconies, and a street view.
A modern hotel room with a stone wall, a staircase, a seating area with two chairs, a small table, and a desk with a phone and a lamp.

4. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
Canada
Dena
AED 458
AED 545 total
includes taxes & fees
6 Nov - 7 Nov
Caportigia Boutique Hotel
A spa room with a large window, a hot tub, and two candles.
A stone building with arched walkways and outdoor seating areas.
A spacious living room with a high ceiling, white sofas, a coffee table, and a large mirror.
A spacious lobby with arched ceilings, a central round table with decorative items, and a modern chandelier.

5. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
United Kingdom
Chris
AED 1,111
AED 1,264 total
includes taxes & fees
25 Oct - 26 Oct
Dimora Caiammari Luxury Hotel & Spa
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.
A table set with breakfast items overlooking a coastal view.
A modern bathroom with a freestanding bathtub, a small table with toiletries, and a view of the ocean.
A modern bathroom with a freestanding bathtub, a round table with a magazine, and a view of a pool and greenery.

6. Minareto

Minareto
Syracuse
United Kingdom
Lekhbiro
AED 1,111
AED 1,263 total
includes taxes & fees
3 Nov - 4 Nov
Minareto
A large swimming pool with a modern building in the background.
A beach with clear turquoise water, sandy shore, and sparse vegetation.
A sauna with wooden benches and a central stone pillar.
An outdoor dining area with tables and chairs, a pool, and palm trees in the background.

7. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
United States
Jeffrey
AED 1,230
AED 1,394 total
includes taxes & fees
6 Nov - 7 Nov
Wellness & Spa Hotel Principe di Fitalia
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Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse
An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Syracuse?
Prepare for 5-star opulence at Grand Hotel Ortigia Siracusa, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Des Ètrangers. These are some of the best stays in Syracuse based on Expedia customer reviews. Book one and get a taste of the finer life!
How much does it cost to stay in a 5-star hotel in Syracuse?
How much you pay for a 5-star hotel in Syracuse depends on factors like when you plan to go and the length of your vacation. Our insider tip for bagging the best deal? Use our pricing filters to compare all of the available hotels for your preferred dates.
  • Search for the lowest price per night
What makes a hotel 5 stars in Syracuse?
From high-end restaurants and fitness centers to swimming pools and superior bedding, the 5-star experience in Syracuse is all about luxury and relaxation. But it calls for more than just upscale amenities to get a 5-star rating. Hotels also have to deliver outstanding guest services like massage treatments, laundry and dry cleaning and 24-hour room service.

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