The Best Business Hotels in Daniel Island, SC from AED 379 in 2026

A street lined with historic buildings, palm trees, and a church tower with a clock.

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Our top choices for Daniel Island business-friendly hotels

An outdoor patio area with a fire pit, seating, and a covered section.

A swimming pool with lounge chairs, a pergola, and a brick building with large windows.

A modern kitchen area with a coffee station featuring three coffee makers labeled 'GOURMET,' 'DECAF,' and 'HOT WATER.' There is a stone pillar and a sign on the wall that reads 'HOMER.'

A modern hotel room with a kitchenette, a bed, a desk, and a television.

1. Home2 Suites by Hilton Charleston Daniel Island

Charleston

Layla

AED 510

AED 582 total

includes taxes & fees

1 Nov - 2 Nov

A spacious dining area with high ceilings, large windows, and a long communal table with bar stools.

A hotel room with a large bed, a bedside table with a lamp, a mirror, and a wooden floor.

A gym with exercise equipment, a wall-mounted TV, and a window with blinds.

A swimming pool with lounge chairs, a fence, and a building with multiple windows and balconies.

2. Hampton Inn Charleston - Daniel Island

Charleston

Angela

AED 434

AED 494 total

includes taxes & fees

2 Nov - 3 Nov

A hotel room with a bed, a sofa, a desk, a chair, and a window with a view.

A modern living room with a sectional sofa, a coffee table, a chair, and a flat-screen TV mounted on the wall.

A modern hotel room with a flat-screen TV, a wooden dresser, a blue sofa, a desk with a chair, and a painting on the wall.

A hotel room with a sofa, two beds, a desk, and a window with a view.

3. Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

Tami

AED 400

AED 461 total

includes taxes & fees

4 Oct - 5 Oct

A pool area with lounge chairs and palm trees.

A hotel outdoor seating area with wicker chairs, a pool, and palm trees.

A modern kitchen with a central island, built-in shelves, and a variety of kitchen appliances.

A modern restaurant with a long counter, multiple dining tables, and a seating area with sofas.

4. Hotel Indigo Mount Pleasant by IHG

Mount Pleasant

Linda C

AED 331

AED 447 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a large island, bar stools, framed pictures on the wall, and a view of the outside.

A hotel room with a bed, desk, chair, television, and a mirror.

A hotel with a swimming pool, outdoor seating, and a gazebo.

A modern hotel lobby with a gray sofa, a wooden coffee table, and a patterned rug.

5. Quality Inn Mt. Pleasant - Charleston

Mount Pleasant

Lori

AED 329

AED 379 total

includes taxes & fees

2 Nov - 3 Nov

A covered outdoor area with a pool, palm trees, and lounge chairs.

A spacious restaurant with high ceilings, exposed beams, and a brick fireplace. Tables are arranged in a U-shape around the fireplace, with hanging pendant lights above.

A covered outdoor lounge area with wicker furniture, a pool, and a view of the beach and marina.

A spacious lobby with high ceilings, a grand chandelier, and a central open area leading to a door.

6. The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

Edyta

AED 612

AED 866 total

includes taxes & fees

27 Oct - 28 Oct

A hotel lobby with a bar area, multiple dining tables, and chairs.

A modern kitchen with a central island, bar stools, and a variety of kitchen appliances.

A spacious lobby with a high ceiling, a staircase with a wooden handrail, and a seating area with patterned cushions.

A rooftop patio with outdoor seating, a fire pit, and a view of a multi-story building with balconies.

7. Hilton Garden Inn Charleston / Mt. Pleasant

Mount Pleasant

Susan

AED 465

AED 526 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.

A clean, well-lit breakfast area with wooden cabinets, a coffee machine, and a microwave.

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

A pool area with lounge chairs and a brick building in the background.

8. Comfort Inn & Suites Patriots Point

Mount Pleasant

Sandra

AED 398

AED 449 total

includes taxes & fees

6 Oct - 7 Oct

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Top Daniel Island Hotel Reviews

Emeline

10/10 Excellent

"Very pleasant and welcoming hotel. Helpful and courteous staff. The coffee and fruit and water on each floor quite a treat and perk."

The Francis Marion Hotel

8/10 Good

"Room service cleaning was lacking. Several items were not replaced. The coffee pots did nor work. They were Hamilton beach. We requested a replacement in one rom with a Keurig that worked. -some trash was not picked up. The hotel was nice well located and very historic. Bathrooms are very small. But in general we like our stay"

Tides Folly Beach, Charleston's Oceanfront Hotel

8/10 Good

"The grouper sandwich was way too slaty. Unfortunately I could not eat it."

Holiday Inn Express Charleston by IHG

8/10 Good

"Staff were very friendly, helpful,polite. The room was very very clean, up to date Breakfast selection both mornings were good with a nice variety. Only two items that came up to speak about. Expedia had us registered for 3 rooms, so that took a while to figure out 2nd item. The one and only elevator for the hotel was out of order the first night and remained that way during our entire stay. Luckily we were only on the 2nd floor, but I had had a Pacemaker implemented a few weeks earlier so navigating the stairs was a bit difficult for me. 2nd"

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

10/10 Excellent

"Fantastic property and staff!"

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Daniel Island Business Hotels

Our top choices for Daniel Island business-friendly hotels

1. Home2 Suites by Hilton Charleston Daniel Island

2. Hampton Inn Charleston - Daniel Island