The Best Business Hotels in Daniel Island, SC from AED 369 in 2026

A street lined with historic buildings, palm trees, and a church tower with a clock.

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Our top choices for Daniel Island business-friendly hotels

An outdoor patio area with a fire pit, seating, and a covered section.

A modern breakfast bar with a 'GOOD MORNING' sign, a 'inspired table' sign, and various breakfast items and appliances.

A modern hotel room with a kitchenette, a bed, a desk, and a television.

A swimming pool with lounge chairs, a pergola, and a brick building with large windows.

1. Home2 Suites by Hilton Charleston Daniel Island

Charleston

Layla

AED 479

AED 546 total

includes taxes & fees

1 Nov - 2 Nov

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.

A hotel room with a sofa, two beds, a desk, and a window with a view.

A modern living room with a sectional sofa, a coffee table, a chair, and a flat-screen TV mounted on the wall.

A modern hotel room with a flat-screen TV, a wooden dresser, a blue sofa, a desk with a chair, and a painting on the wall.

2. Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

Naomi

AED 511

AED 585 total

includes taxes & fees

18 Oct - 19 Oct

A pool area with lounge chairs and palm trees.

A hotel outdoor seating area with wicker chairs, a pool, and palm trees.

A modern kitchen with a central island, built-in shelves, and a variety of kitchen appliances.

A paved pathway leading to a building with large trees and hanging moss.

3. Hotel Indigo Mount Pleasant by IHG

Mount Pleasant

Jennifer

AED 389

AED 513 total

includes taxes & fees

16 Nov - 17 Nov

A hotel lobby with a bar area, multiple dining tables, and chairs.

A spacious lobby with a high ceiling, a staircase with a wooden handrail, and a seating area with patterned cushions.

A modern kitchen with a central island, bar stools, and a variety of kitchen appliances.

A rooftop patio with outdoor seating, a fire pit, and a view of a multi-story building with balconies.

4. Hilton Garden Inn Charleston / Mt. Pleasant

Mount Pleasant

Katie

AED 434

AED 490 total

includes taxes & fees

1 Nov - 2 Nov

A hotel with a swimming pool, outdoor seating, and a gazebo.

A swimming pool with a lifeguard stand, lounge chairs, and a building with a balcony in the background.

A motel with a covered parking area, a flagpole with an American flag, and a sign indicating 'OPEN 24 HOURS.'

A hotel room with a bed, two bedside tables, a chair, a desk, and a mirror.

5. Quality Inn Mt. Pleasant - Charleston

Mount Pleasant

Lori

AED 320

AED 369 total

includes taxes & fees

9 Nov - 10 Nov

A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.

A pool area with lounge chairs and a brick building in the background.

A clean, well-lit breakfast area with wooden cabinets, a coffee machine, and a microwave.

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

6. Comfort Inn & Suites Patriots Point

Mount Pleasant

Trevor

AED 386

AED 437 total

includes taxes & fees

10 Nov - 11 Nov

A multi-story hotel with a brick facade, large windows, and outdoor seating areas.

A swimming pool with a lifeguard stand, lounge chairs, and a covered seating area.

A spacious hotel lobby with a stone accent wall, multiple seating areas, and a bar.

A hotel room with a bed, a desk, a sofa, a TV, and a window with curtains.

7. Staybridge Suites Charleston - Mount Pleasant by IHG

Mount Pleasant

Janice

AED 496

AED 568 total

includes taxes & fees

1 Nov - 2 Nov

A covered outdoor area with a pool, palm trees, and lounge chairs.

A spacious lobby with high ceilings, a grand chandelier, and a central open area leading to a door.

A spacious restaurant with high ceilings, exposed beams, and a brick fireplace. Tables are arranged in a U-shape around the fireplace, with hanging pendant lights above.

A beachside walkway with bicycles, colorful chairs, and palm trees.

8. The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

Robert

AED 632

AED 888 total

includes taxes & fees

15 Nov - 16 Nov

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Top Daniel Island Hotel Reviews

Hotel Indigo Mount Pleasant by IHG

10/10 Excellent

"All good. very clean, great parking, pool.."

Emeline

10/10 Excellent

"Though we did not use the bikes, I think that's such a nice amenity! Record players over and we're all so nice touch and a location was perfect."

The Ryder Hotel

8/10 Good

"The room was very fresh and modern. The pool area and bar were lively and well maintained. The pool area, front desk and restaurant/bar staff were really pleasant. The cafe was overpriced for what was served and the cafe morning staff didn’t have much personality. But there are other coffee options nearby!"

Harborside at Charleston Harbor Resort and Marina

10/10 Excellent

"Great location and amenities. Staff was friendly and helpful."

Tides Folly Beach, Charleston's Oceanfront Hotel

8/10 Good

"Clean rooms food and entertainment within walking distance."

The Vendue

8/10 Good

"We enjoyed our 4 night stay and visit to Charleston. The Vendue staff were very friendly and helpful. We were given Champagne during registration which was a fun touch. Familiar faces were always there to greet us as we came and went. In the evenings, sherry and a sweet treat were available in the lobby. Every morning we had a goody bag with croissant and fruit. The only problem we had was the first night we didn’t get our room in the Enclave, but the 2nd night they moved us over and everything was great. Walkable distance to many sights, art galleries, and restaurants. Fabulous!"

Holiday Inn Express & Suites Charleston DWTN - Medical CTR by IHG

10/10 Excellent

"Great location, very close to downtown Charleston. The rooms are comfortable, and the breakfast is excellent, with a great variety of options. Overall, a very nice place to stay!"

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Check availability on Daniel Island Business Hotels

Our top choices for Daniel Island business-friendly hotels

1. Home2 Suites by Hilton Charleston Daniel Island